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Ontogeny and Cross-species Comparison of Pathways Involved in Drug Absorption, Distribution, Metabolism, and Excretion in Neonates (Review): Kidney

Drug metabolism and disposition, 2020-05, Vol.48 (5), p.353-367

2020

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Drug-induced Physeal Abnormalities in Preclinical Toxicity Studies

Toxicologic pathology, 2017-10, Vol.45 (7), p.869-875

Frazier, Kendall S.

2017

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Proliferative and Nonproliferative Lesions of the Rat and Mouse Urinary System

Toxicologic pathology, 2012-06, Vol.40 (4_suppl), p.14S-86S

2012

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Antisense Oligonucleotide Therapies: The Promise and the Challenges from a Toxicologic Pathologist’s Perspective

Toxicologic pathology, 2015-01, Vol.43 (1), p.78-89

Frazier, Kendall S.

2015

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Intrarenal Renin–Angiotensin System Involvement in the Pathogenesis of Chronic Progressive Nephropathy—Bridging the Informational Gap Between Disciplines

Toxicologic Pathology, 2019-10, Vol.47 (7), p.799-816

2019

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Kidney Effects by Alternative Classes of Medicines in Patients and Relationship to Effects in Nonclinical Toxicity Studies

Toxicologic Pathology, 2022-06, Vol.50 (4), p.408-414

Frazier, Kendall S.

2022

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The Impact of Functional and Structural Maturation of the Kidney on Susceptibility to Drug and Chemical Toxicity in Neonatal Rodents

Toxicologic pathology, 2021-12, Vol.49 (8), p.1377-1388

Frazier, Kendall S.

2021

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Protein Extraction of Formalin-fixed, Paraffin-embedded Tissue Enables Robust Proteomic Profiles by Mass Spectrometry

The journal of histochemistry and cytochemistry, 2009-09, Vol.57 (9), p.849-860

2009

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Tumor-Specific Efficacy of Transforming Growth Factor-βRI Inhibition in Eker Rats

Clinical cancer research, 2007-05, Vol.13 (10), p.3087-3099

2007

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A Review of Specific Biomarkers of Chronic Renal Injury and Their Potential Application in Nonclinical Safety Assessment Studies

Toxicologic Pathology, 2021-07, Vol.49 (5), p.996-1023

2021

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Toxicologic Pathology Forum Opinion Paper: Recommendations for a Tiered Approach to Nonclinical Mechanistic Nephrotoxicity Evaluation

Toxicologic pathology, 2018-08, Vol.46 (6), p.636-646

2018

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Drug-induced Glomerulonephritis: The Spectre of Biotherapeutic and Antisense Oligonucleotide Immune Activation in the Kidney

Toxicologic pathology, 2018-12, Vol.46 (8), p.904-917

2018

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Differences in Effects on Myocardium and Mitochondria by Angiogenic Inhibitors Suggest Separate Mechanisms of Cardiotoxicity

Toxicologic pathology, 2010-08, Vol.38 (5), p.691-702

2010

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Species Differences in Renal Development and Associated Developmental Nephrotoxicity

Birth defects research, 2017-10, Vol.109 (16), p.1243-1256

Frazier, Kendall S.

2017

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Imaging MS in Toxicology: An Investigation of Juvenile Rat Nephrotoxicity Associated with Dabrafenib Administration

Journal of the American Society for Mass Spectrometry, 2015-06, Vol.26 (6), p.887-898

2015

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Regulatory Forum Opinion Piece: Dispelling Confusing Pathology Terminology: Recognition and Interpretation of Selected Rodent Renal Tubule Lesions

Toxicologic pathology, 2015-06, Vol.43 (4), p.457-463

2015

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Carcinogenicity Assessment of Daprodustat (GSK1278863), a Hypoxia-Inducible Factor (HIF)-Prolyl Hydroxylase Inhibitor

Toxicologic pathology, 2020-02, Vol.48 (2), p.362-378

2020

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Kidney Pathology and Investigative Nephrotoxicology Strategies Across Species

Seminars in nephrology, 2019-03, Vol.39 (2), p.190-201

2019

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Renal Papillary Rarefaction: An Artifact Mimicking Papillary Necrosis

Toxicologic pathology, 2019-07, Vol.47 (5), p.645-648

2019

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Scientific and Regulatory Policy Committee Points-to-consider Paper: Drug-induced Vascular Injury Associated with Nonsmall Molecule Therapeutics in Preclinical Development: Part 2. Antisense Oligonucleotides

Toxicologic pathology, 2015-10, Vol.43 (7), p.935-944

2015

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Role of p38 in regulation of hematopoiesis: Effect of p38 inhibition on cytokine production and transcription factor activity in human bone marrow stromal cells

Blood cells, molecules, & diseases, 2008-05, Vol.40 (3), p.370-380

2008

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Scientific and Regulatory Policy Committee Points-to-consider Paper: Drug-induced Vascular Injury Associated with Nonsmall Molecule Therapeutics in Preclinical Development: Part I. Biotherapeutics

Toxicologic pathology, 2015-10, Vol.43 (7), p.915-934

2015

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Drug safety Africa: An overview of safety pharmacology & toxicology in South Africa

Journal of pharmacological and toxicological methods, 2019-07, Vol.98, p.106579, Article 106579

2019

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Scientific and Regulatory Policy Committee Review: Review of the Organisation for Economic Co-operation and Development (OECD) Guidance on the GLP Requirements for Peer Review of Histopathology

Toxicologic pathology, 2015-10, Vol.43 (7), p.907-914

2015

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Ontogeny and Cross-species Comparison of Pathways Involved in Drug Absorption, Distribution, Metabolism, and Excretion in Neonates (Review): Kidney

Drug-induced Physeal Abnormalities in Preclinical Toxicity Studies

Proliferative and Nonproliferative Lesions of the Rat and Mouse Urinary System

Antisense Oligonucleotide Therapies: The Promise and the Challenges from a Toxicologic Pathologist’s Perspective

Intrarenal Renin–Angiotensin System Involvement in the Pathogenesis of Chronic Progressive Nephropathy—Bridging the Informational Gap Between Disciplines

Kidney Effects by Alternative Classes of Medicines in Patients and Relationship to Effects in Nonclinical Toxicity Studies

The Impact of Functional and Structural Maturation of the Kidney on Susceptibility to Drug and Chemical Toxicity in Neonatal Rodents

Protein Extraction of Formalin-fixed, Paraffin-embedded Tissue Enables Robust Proteomic Profiles by Mass Spectrometry

Species-specific Inflammatory Responses as a Primary Component for the Development of Glomerular Lesions in Mice and Monkeys Following Chronic Administration of a Second-generation Antisense Oligonucleotide

Tumor-Specific Efficacy of Transforming Growth Factor-βRI Inhibition in Eker Rats

A Review of Specific Biomarkers of Chronic Renal Injury and Their Potential Application in Nonclinical Safety Assessment Studies

Toxicologic Pathology Forum Opinion Paper: Recommendations for a Tiered Approach to Nonclinical Mechanistic Nephrotoxicity Evaluation

Drug-induced Glomerulonephritis: The Spectre of Biotherapeutic and Antisense Oligonucleotide Immune Activation in the Kidney

Differences in Effects on Myocardium and Mitochondria by Angiogenic Inhibitors Suggest Separate Mechanisms of Cardiotoxicity

Species Differences in Renal Development and Associated Developmental Nephrotoxicity

Imaging MS in Toxicology: An Investigation of Juvenile Rat Nephrotoxicity Associated with Dabrafenib Administration

Regulatory Forum Opinion Piece: Dispelling Confusing Pathology Terminology: Recognition and Interpretation of Selected Rodent Renal Tubule Lesions

Carcinogenicity Assessment of Daprodustat (GSK1278863), a Hypoxia-Inducible Factor (HIF)-Prolyl Hydroxylase Inhibitor

Kidney Pathology and Investigative Nephrotoxicology Strategies Across Species

Renal Papillary Rarefaction: An Artifact Mimicking Papillary Necrosis

Scientific and Regulatory Policy Committee Points-to-consider Paper: Drug-induced Vascular Injury Associated with Nonsmall Molecule Therapeutics in Preclinical Development: Part 2. Antisense Oligonucleotides

Role of p38 in regulation of hematopoiesis: Effect of p38 inhibition on cytokine production and transcription factor activity in human bone marrow stromal cells

Scientific and Regulatory Policy Committee Points-to-consider Paper: Drug-induced Vascular Injury Associated with Nonsmall Molecule Therapeutics in Preclinical Development: Part I. Biotherapeutics

Drug safety Africa: An overview of safety pharmacology & toxicology in South Africa

Scientific and Regulatory Policy Committee Review: Review of the Organisation for Economic Co-operation and Development (OECD) Guidance on the GLP Requirements for Peer Review of Histopathology

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