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Mini-Review: Induced pluripotent stem cells and the search for new cell-specific ALS therapeutic targets

Neuroscience letters, 2021-06, Vol.755, p.135911-135911, Article 135911

2021

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New In Vitro Models to Study Amyotrophic Lateral Sclerosis

Brain pathology (Zurich, Switzerland), 2016-03, Vol.26 (2), p.258-265

2016

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Blood-Brain Barrier Disruption and Its Involvement in Neurodevelopmental and Neurodegenerative Disorders

International journal of molecular sciences, 2022-12, Vol.23 (23), p.15271

2022

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DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity

Cellular and molecular life sciences : CMLS, 2021-08, Vol.78 (15), p.5707-5729

2021

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Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis

Nature reviews. Neurology, 2011-11, Vol.7 (11), p.616

2011

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Improving Single Injection CSF Delivery of AAV9-mediated Gene Therapy for SMA: A Dose–response Study in Mice and Nonhuman Primates

Molecular therapy, 2015-03, Vol.23 (3), p.477-487

2015

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Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (50), p.E6993-E7002

2015

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Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (2), p.829-832

2014

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Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism

Proceedings of the National Academy of Sciences - PNAS, 2016-10, Vol.113 (42), p.E6496-E6505

2016

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C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis

Brain (London, England : 1878), 2019-12, Vol.142 (12), p.3771-3790

2019

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Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis

Brain (London, England : 1878), 2011-09, Vol.134 (9), p.2627-2641

2011

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Therapeutic AAV9-mediated Suppression of Mutant SOD1 Slows Disease Progression and Extends Survival in Models of Inherited ALS

Molecular therapy, 2013-12, Vol.21 (12), p.2148-2159

2013

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Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis

Nature medicine, 2016-04, Vol.22 (4), p.397-403

2016

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Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS

EBioMedicine, 2019-02, Vol.40, p.626-635

2019

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Biological and methodological complexities of beta‐amyloid peptide: Implications for Alzheimer’s disease research

Journal of neurochemistry, 2022-02, Vol.160 (4), p.434-453

2022

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SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits

Nature communications, 2017-07, Vol.8 (1), p.16063-18, Article 16063

2017

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Towards 3D Bioprinted Spinal Cord Organoids

International journal of molecular sciences, 2022-05, Vol.23 (10), p.5788

2022

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Mitochondrial Dysfunction in Alzheimer's Disease: A Biomarker of the Future?

Biomedicines, 2021-01, Vol.9 (1), p.63

2021

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Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons

Scientific reports, 2020-09, Vol.10 (1), p.15485-14, Article 15485

2020

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Microarray Analysis of the Cellular Pathways Involved in the Adaptation to and Progression of Motor Neuron Injury in the SOD1 G93A Mouse Model of Familial ALS

The Journal of neuroscience, 2007-08, Vol.27 (34), p.9201-9219

2007

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Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis

Brain (London, England : 1878), 2013-11, Vol.136 (Pt 11), p.3305-3332

2013

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Astrocytic C-X-C motif chemokine ligand-1 mediates β-amyloid-induced synaptotoxicity

Journal of neuroinflammation, 2021-12, Vol.18 (1), p.306-306, Article 306

2021

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Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS)

PloS one, 2010-03, Vol.5 (3), p.e9872-e9872

2010

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Emerging Mechanisms Underpinning Neurophysiological Impairments in C9ORF72 Repeat Expansion-Mediated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia

Frontiers in cellular neuroscience, 2021-12, Vol.15, p.784833-784833

2021

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Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease

Nature communications, 2024-06, Vol.15 (1), p.4695-18, Article 4695

2024

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Mini-Review: Induced pluripotent stem cells and the search for new cell-specific ALS therapeutic targets

New In Vitro Models to Study Amyotrophic Lateral Sclerosis

Blood-Brain Barrier Disruption and Its Involvement in Neurodevelopmental and Neurodegenerative Disorders

DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity

Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis

Improving Single Injection CSF Delivery of AAV9-mediated Gene Therapy for SMA: A Dose–response Study in Mice and Nonhuman Primates

Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS

Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS

Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism

C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis

Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis

Therapeutic AAV9-mediated Suppression of Mutant SOD1 Slows Disease Progression and Extends Survival in Models of Inherited ALS

Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis

Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS

Biological and methodological complexities of beta‐amyloid peptide: Implications for Alzheimer’s disease research

SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits

Towards 3D Bioprinted Spinal Cord Organoids

Mitochondrial Dysfunction in Alzheimer's Disease: A Biomarker of the Future?

Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons

Microarray Analysis of the Cellular Pathways Involved in the Adaptation to and Progression of Motor Neuron Injury in the SOD1 G93A Mouse Model of Familial ALS

Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis

Astrocytic C-X-C motif chemokine ligand-1 mediates β-amyloid-induced synaptotoxicity

Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS)

Emerging Mechanisms Underpinning Neurophysiological Impairments in C9ORF72 Repeat Expansion-Mediated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia

Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease

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