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Optimization of 3-(1H-Indazol-3-ylmethyl)-1,5-benzodiazepines as Potent, Orally Active CCK-A Agonists

Journal of medicinal chemistry, 1997-08, Vol.40 (17), p.2706-2725

1997

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Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity. 1. Optimization of the Agonist “Trigger”

Journal of medicinal chemistry, 1996-01, Vol.39 (2), p.562-569

1996

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1,4-Benzodiazepine Peripheral Cholecystokinin (CCK-A) Receptor Agonists

Bioorganic & medicinal chemistry letters, 2001-05, Vol.11 (9), p.1145-1148

2001

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3-(1H-Indazol-3-ylmethyl)-1,5-benzodiazepines: CCK-A Agonists That Demonstrate Oral Activity as Satiety Agents

Journal of medicinal chemistry, 1996-07, Vol.39 (14), p.2655-2658

1996

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Potential Corticotropin-Releasing Factor Pathways in the Rat Brain as Determined by Bilateral Electrolytic Lesions of the Central Amygdaloid Nucleus and the Paraventricular Nucleus of the Hypothalamus

Journal of neuroendocrinology, 1993-02, Vol.5 (1), p.95-98

1993

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Neurotensin blocks certain amphetamine-induced behaviours

Nature (London), 1981-05, Vol.291 (5810), p.73-76

1981

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Modification of Receptor Selectivity and Functional Activity in Cholecystokinin Peptoid Ligands

Journal of medicinal chemistry, 1995-08, Vol.38 (17), p.3384-3390

1995

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Cholecystokinin octapeptide and lithium produce different effects on feeding and taste aversion learning

Physiology & behavior, 1986, Vol.36 (3), p.507-512

1986

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Thyrotropin-releasing hormone and amphetamine produce different patterns of behavioral excitation in rats

European journal of pharmacology, 1981-06, Vol.72 (1), p.35-43

1981

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Growth, endocrinological and behavioral deficits after monosodium l-glutamate in the neonatal rat: possible involvement of arcuate dopamine neuron damage

Psychoneuroendocrinology, 1977, Vol.2 (2), p.179-196

1977

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Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity (II): Optimization of the C3 Amino Substituent

Journal of medicinal chemistry, 1996-12, Vol.39 (26), p.5236-5245

1996

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Sulfated Cholecystokinin [26–33]Induces Mild Taste Aversion Conditioning in Rats when Administered by Three Different Routes

Peptides (New York, N.Y. : 1980), 1998-01, Vol.19 (5), p.849-857

1998

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Cholecystokinin and Satiety: A Time Line

Annals of the New York Academy of Sciences, 1994-03, Vol.713 (1), p.232-235

1994

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Multiple, small doses of cholecystokinin octapeptide are more efficacious at inducing taste aversion conditioning than single, large doses

Peptides (New York, N.Y. : 1980), 1995, Vol.16 (3), p.539-545

1995

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Several roles of CCKA and CCKB receptor subtypes in CCK-8-induced and LiCl-induced taste aversion conditioning

Peptides (New York, N.Y. : 1980), 1996, Vol.17 (3), p.483-488

1996

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Several roles of CCK A and CCK B receptor subtypes in CCK-8-induced and LiCl-induced taste aversion conditioning

Peptides (New York, N.Y. : 1980), 1996, Vol.17 (3), p.483-488

1996

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Interactions of neurotensin with dopamine-containing neurons in the central nervous system

Progress in neuro-psychopharmacology & biological psychiatry, 1988, Vol.12, p.S53-S69

1988

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Intra‐Accinnbens Injection of Neurotensin Antagonizes the Behavioral Supersensitivity to L‐DOPA in Dopamine‐Denervated Ratsa

Annals of the New York Academy of Sciences, 1988-10, Vol.537 (1), p.496-497

1988

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Intra-Accinnbens Injection of Neurotensin Antagonizes the Behavioral Supersensitivity to L-DOPA in Dopamine-Denervated Rats

Annals of the New York Academy of Sciences, 1988-10, Vol.537 (1), p.496-497

1988

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Alterations in Nociception and Body Temperature after Intracisternal Administration of Neurotensin, $\beta $-endorphin, other Endogenous Peptides, and Morphine

Proceedings of the National Academy of Sciences - PNAS, 1979-10, Vol.76 (10), p.5368-5371

1979

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Antagonization of the behavioral activation produced by direct stimulation of forebrain dopamine receptors caused by intraaccumbens injections of neurotensin

Neuropsychopharmacology (New York, N.Y.), 1988-09, Vol.1 (3), p.243-250

1988

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Evidence that taste aversion learning induced by l-5-hydroxytryptophan is mediated peripherally

Pharmacology, biochemistry and behavior, 1984-01, Vol.20 (5), p.799-802

1984

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Buspirone antagonizes the expression of conditioned taste aversion in rats

Drug development research, 1987, Vol.11 (2), p.87-95

1987

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Different behavioral responses to l-DOPA after anterolateral or posterolateral hypothalamic injections of 6-hydroxydopamine

Brain research, 1977-09, Vol.132 (3), p.507-520

1977

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Hypothalamic and locus coeruleus self-stimulation are decreased by cholecystokinin

Physiology & behavior, 1978-12, Vol.21 (6), p.1037-1041

1978

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Optimization of 3-(1H-Indazol-3-ylmethyl)-1,5-benzodiazepines as Potent, Orally Active CCK-A Agonists

Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity. 1. Optimization of the Agonist “Trigger”

1,4-Benzodiazepine Peripheral Cholecystokinin (CCK-A) Receptor Agonists

3-(1H-Indazol-3-ylmethyl)-1,5-benzodiazepines: CCK-A Agonists That Demonstrate Oral Activity as Satiety Agents

Potential Corticotropin-Releasing Factor Pathways in the Rat Brain as Determined by Bilateral Electrolytic Lesions of the Central Amygdaloid Nucleus and the Paraventricular Nucleus of the Hypothalamus

Neurotensin blocks certain amphetamine-induced behaviours

Modification of Receptor Selectivity and Functional Activity in Cholecystokinin Peptoid Ligands

Cholecystokinin octapeptide and lithium produce different effects on feeding and taste aversion learning

Thyrotropin-releasing hormone and amphetamine produce different patterns of behavioral excitation in rats

Growth, endocrinological and behavioral deficits after monosodium l-glutamate in the neonatal rat: possible involvement of arcuate dopamine neuron damage

Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity (II): Optimization of the C3 Amino Substituent

Sulfated Cholecystokinin [26–33]Induces Mild Taste Aversion Conditioning in Rats when Administered by Three Different Routes

Cholecystokinin and Satiety: A Time Line

Multiple, small doses of cholecystokinin octapeptide are more efficacious at inducing taste aversion conditioning than single, large doses

Several roles of CCKA and CCKB receptor subtypes in CCK-8-induced and LiCl-induced taste aversion conditioning

Several roles of CCK A and CCK B receptor subtypes in CCK-8-induced and LiCl-induced taste aversion conditioning

Interactions of neurotensin with dopamine-containing neurons in the central nervous system

Intra‐Accinnbens Injection of Neurotensin Antagonizes the Behavioral Supersensitivity to L‐DOPA in Dopamine‐Denervated Ratsa

Intra-Accinnbens Injection of Neurotensin Antagonizes the Behavioral Supersensitivity to L-DOPA in Dopamine-Denervated Rats

Alterations in Nociception and Body Temperature after Intracisternal Administration of Neurotensin, $\beta $-endorphin, other Endogenous Peptides, and Morphine

Antagonization of the behavioral activation produced by direct stimulation of forebrain dopamine receptors caused by intraaccumbens injections of neurotensin

Evidence that taste aversion learning induced by l-5-hydroxytryptophan is mediated peripherally

Buspirone antagonizes the expression of conditioned taste aversion in rats

Different behavioral responses to l-DOPA after anterolateral or posterolateral hypothalamic injections of 6-hydroxydopamine

Hypothalamic and locus coeruleus self-stimulation are decreased by cholecystokinin

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