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Epitope Discovery for a Synthetic Polymer Nanoparticle: A New Strategy for Developing a Peptide Tag

Journal of the American Chemical Society, 2014-01, Vol.136 (4), p.1194-1197

2014

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The R1275Q Neuroblastoma Mutant and Certain ATP-competitive Inhibitors Stabilize Alternative Activation Loop Conformations of Anaplastic Lymphoma Kinase

The Journal of biological chemistry, 2012-10, Vol.287 (44), p.37447-37457

2012

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Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck: Synthesis, SAR, and in Vivo Anti-Inflammatory Activity

Journal of medicinal chemistry, 2006-09, Vol.49 (19), p.5671-5686

2006

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Metal-Free Polymer-Based Affinity Medium for Selective Purification of His6-Tagged Proteins

Biomacromolecules, 2021-04, Vol.22 (4), p.1695-1705

2021

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Selective Inhibitors of the Mutant B-Raf Pathway: Discovery of a Potent and Orally Bioavailable Aminoisoquinoline

Journal of medicinal chemistry, 2009-10, Vol.52 (20), p.6189-6192

2009

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The Discovery and Optimization of a Novel Class of Potent, Selective, and Orally Bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with Potential Utility for the Treatment of Cancer

Journal of medicinal chemistry, 2012-07, Vol.55 (14), p.6523-6540

2012

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Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling

Bioorganic & medicinal chemistry, 2016-05, Vol.24 (10), p.2215-2234

2016

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Corrigendum to “Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling” [Bioorg. Med. Chem. 24 (2016) 2215–2234]

Bioorganic & medicinal chemistry, 2016-07, Vol.24 (13), p.3093-3093

2016

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Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck: Synthesis, SAR, and in Vivo Antiinflammatory Activity

Journal of medicinal chemistry, 2006-08, Vol.49 (16), p.4981-4991

2006

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Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (8), p.2394-2399

2011

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Evaluation of recombinant monoclonal antibody SVmab1 binding to Na V1.7 target sequences and block of human Na V1.7 currents

F1000 research, 2016-01, Vol.5, p.2764-2764

2016

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N-(3-(Phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: Structure, synthesis and SAR

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.1172-1176

2008

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Conformational Diversity of Catalytic Cores of Protein Kinases

Pharmacology & therapeutics (Oxford), 1999-05, Vol.82 (2), p.157-164

1999

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Evaluation of recombinant monoclonal antibody SVmab1 binding to NaV1.7 target sequences and block of human NaV1.7 currents

F1000 research, 2016, Vol.5, p.2764

2016

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Evaluation of recombinant monoclonal antibody SVmab1 binding to Na V 1.7 target sequences and block of human Na V 1.7 currents

F1000 research, 2016, Vol.5, p.2764

2016

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The Discovery and Optimization of a Novel Class of Potent, Selective, and Orally Bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with Potential Utility for the Treatment of Cancer

Journal of medicinal chemistry, 2012-07, Vol.55 (14)

2012

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Regulation of steroid hormone biosynthesis. Identification of precursors of a phosphoprotein targeted to the mitochondrion in stimulated rat adrenal cortex cells

The Journal of biological chemistry, 1991-10, Vol.266 (29), p.19739-19745

1991

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Abstract 2681A: Structure-guided design of potent and selective inhibitors of B-Raf kinase displaying on-mechanism in vivo activity

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.2681-2681A

2010

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ATP-dependent transport of organic anions in secretory vesicles of Saccharomyces cerevisiae

Proceedings of the National Academy of Sciences - PNAS, 1994-09, Vol.91 (20), p.9476-9479

1994

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Acute action of luteinizing hormone on mouse Leydig cells: Accumulation of mitochondrial phosphoproteins and stimulation of testosterone synthesis

Molecular and cellular endocrinology, 1991-10, Vol.81 (1), p.113-126

1991

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The role of thiols in ATP-dependent transport of S-(2,4-dinitrophenyl) glutathione by rat liver plasma membrane vesicles

Biochimica et biophysica acta, 1996-02, Vol.1279 (1), p.35-42

1996

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ATP-dependent transport of organic anions in secretory vesicles of Saccaromyces cerevisiae

Proceedings of the National Academy of Sciences - PNAS, 1994-09, Vol.91 (20), p.9476

1994

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Acute cAMP Stimulation in Leydig Cells: Rapid Accumulation of a Protein Similar to That Detected in Adrenal Cortex and Corpus Luteum

Endocrine research, 1986, Vol.12 (4), p.429-446

1986

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Epitope Discovery for a Synthetic Polymer Nanoparticle: A New Strategy for Developing a Peptide Tag

The R1275Q Neuroblastoma Mutant and Certain ATP-competitive Inhibitors Stabilize Alternative Activation Loop Conformations of Anaplastic Lymphoma Kinase

Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck: Synthesis, SAR, and in Vivo Anti-Inflammatory Activity

Metal-Free Polymer-Based Affinity Medium for Selective Purification of His6-Tagged Proteins

Selective Inhibitors of the Mutant B-Raf Pathway: Discovery of a Potent and Orally Bioavailable Aminoisoquinoline

The Discovery and Optimization of a Novel Class of Potent, Selective, and Orally Bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with Potential Utility for the Treatment of Cancer

Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling

Structure-Based Design of Novel 2-Amino-6-phenyl-pyrimido[5′,4′:5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as Potent and Orally Active Inhibitors of Lymphocyte Specific Kinase (Lck): Synthesis, SAR, and In Vivo Anti-Inflammatory Activity

Corrigendum to “Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling” [Bioorg. Med. Chem. 24 (2016) 2215–2234]

Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck: Synthesis, SAR, and in Vivo Antiinflammatory Activity

Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors

Evaluation of recombinant monoclonal antibody SVmab1 binding to Na V1.7 target sequences and block of human Na V1.7 currents

Structure-Guided Design of Aminopyrimidine Amides as Potent, Selective Inhibitors of Lymphocyte Specific Kinase: Synthesis, Structure–Activity Relationships, and Inhibition of in Vivo T Cell Activation

N-(3-(Phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: Structure, synthesis and SAR

Conformational Diversity of Catalytic Cores of Protein Kinases

Evaluation of recombinant monoclonal antibody SVmab1 binding to NaV1.7 target sequences and block of human NaV1.7 currents

Evaluation of recombinant monoclonal antibody SVmab1 binding to Na V 1.7 target sequences and block of human Na V 1.7 currents

The Discovery and Optimization of a Novel Class of Potent, Selective, and Orally Bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with Potential Utility for the Treatment of Cancer

Regulation of steroid hormone biosynthesis. Identification of precursors of a phosphoprotein targeted to the mitochondrion in stimulated rat adrenal cortex cells

Abstract 2681A: Structure-guided design of potent and selective inhibitors of B-Raf kinase displaying on-mechanism in vivo activity

ATP-dependent transport of organic anions in secretory vesicles of Saccharomyces cerevisiae

Acute action of luteinizing hormone on mouse Leydig cells: Accumulation of mitochondrial phosphoproteins and stimulation of testosterone synthesis

The role of thiols in ATP-dependent transport of S-(2,4-dinitrophenyl) glutathione by rat liver plasma membrane vesicles

ATP-dependent transport of organic anions in secretory vesicles of Saccaromyces cerevisiae

Acute cAMP Stimulation in Leydig Cells: Rapid Accumulation of a Protein Similar to That Detected in Adrenal Cortex and Corpus Luteum

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