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The bactericidal/permeability-increasing protein (BPI) in antibacterial host defense

Journal of leukocyte biology, 1998-07, Vol.64 (1), p.14-18

Elsbach, Peter

1998

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What is the real role of antimicrobial polypeptides that can mediate several other inflammatory responses?

The Journal of clinical investigation, 2003-06, Vol.111 (11), p.1643-1645

Elsbach, Peter

2003

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The potent anti-Staphylococcus aureus activity of a sterile rabbit inflammatory fluid is due to a 14-kD phospholipase A2

The Journal of clinical investigation, 1996-01, Vol.97 (1), p.250-257

1996

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High-affinity binding of the bactericidal/permeability-increasing protein and a recombinant amino-terminal fragment to the lipid A region of lipopolysaccharide

Infection and Immunity, 1992-11, Vol.60 (11), p.4754-4761

1992

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Structural determinants of the action against Escherichia coli of a human inflammatory fluid phospholipase A2 in concert with polymorphonuclear leukocytes

The Journal of biological chemistry, 1994-10, Vol.269 (42), p.26331-26337

1994

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Human bactericidal/permeability-increasing protein and a recombinant NH2-terminal fragment cause killing of serum-resistant Gram-negative bacteria in whole blood and inhibit tumor necrosis factor release induced by the bacteria

The Journal of clinical investigation, 1992-09, Vol.90 (3), p.1122-1130

1992

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Role of the bactericidal/permeability-increasing protein in host defence

Current opinion in immunology, 1998-02, Vol.10 (1), p.45-49

1998

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Bacterial lipopolysaccharide primes human neutrophils for enhanced release of arachidonic acid and causes phosphorylation of an 85-kD cytosolic phospholipase A2

The Journal of clinical investigation, 1994-04, Vol.93 (4), p.1583-1591

1994

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Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations

The Journal of biological chemistry, 1989-06, Vol.264 (16), p.9505-9509

1989

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Antibacterial 15-kDa protein isoforms (p15s) are members of a novel family of leukocyte proteins

The Journal of biological chemistry, 1993-03, Vol.268 (8), p.6058-6063

1993

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Individual and synergistic effects of rabbit granulocyte proteins on Escherichia coli

The Journal of clinical investigation, 1994-08, Vol.94 (2), p.672-682

1994

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Effect of lipopolysaccharide (LPS) chain length on interactions of bactericidal/permeability-increasing protein and its bioactive 23-kilodalton NH2-terminal fragment with isolated LPS and intact Proteus mirabilis and Escherichia coli

Infection and Immunity, 1994-01, Vol.62 (1), p.259-265

1994

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A 25-kDa NH2-terminal fragment carries all the antibacterial activities of the human neutrophil 60-kDa bactericidal/permeability-increasing protein

The Journal of biological chemistry, 1987-11, Vol.262 (31), p.14891-14894

1987

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Purification of a cellular (granulocyte) and an extracellular (serum) phospholipase A2 that participate in the destruction of Escherichia coli in a rabbit inflammatory exudate

The Journal of biological chemistry, 1990-04, Vol.265 (12), p.6675-6681

1990

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A recombinant amino terminal fragment of bactericidal/permeability-increasing protein inhibits the induction of leukocyte responses by LPS

Journal of leukocyte biology, 1993-12, Vol.54 (6), p.558-563

1993

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Separation of sublethal and lethal effects of the bactericidal/permeability increasing protein on Escherichia coli

The Journal of clinical investigation, 1990-03, Vol.85 (3), p.853-860

1990

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[2] Utilization of labeled Escherichia coli as phospholipase substrate

Methods in Enzymology, 1991, Vol.197, p.24-31

1991

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The Carboxyl-terminal Domain of Closely Related Endotoxin-binding Proteins Determines the Target of Protein-Lipopolysaccharide Complexes

The Journal of biological chemistry, 2002-03, Vol.277 (10), p.7970-7978

2002

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Mechanisms of disposal of bacterial lipopolysaccharides by animal hosts

Microbes and Infection, 2000-08, Vol.2 (10), p.1171-1180

Elsbach, Peter

2000

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Potent CD14-mediated signalling of human leukocytes by Escherichia coli can be mediated by interaction of whole bacteria and host cells without extensive prior release of endotoxin

Infection and Immunity, 1996-09, Vol.64 (9), p.3592-3600

1996

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An Opsonic Function of the Neutrophil Bactericidal/Permeability-Increasing Protein Depends on Both Its N- and C-Terminal Domains

Proceedings of the National Academy of Sciences - PNAS, 1997-09, Vol.94 (20), p.10973-10978

1997

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Separation of sublethal and lethal effects of polymorphonuclear leukocytes on Escherichia coli

The Journal of clinical investigation, 1990-08, Vol.86 (2), p.631-641

1990

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Purification and characterization of a potent bactericidal and membrane active protein from the granules of human polymorphonuclear leukocytes

The Journal of biological chemistry, 1978-04, Vol.253 (8), p.2664-2672

1978

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Prospects for use of recombinant BPI in the treatment of gram-negative bacterial infections

Infectious agents and disease, 1995-06, Vol.4 (2), p.102

1995

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Cell-wall determinants of the bactericidal action of group IIA phospholipase A2 against Gram-positive bacteria

The Journal of clinical investigation, 1999-03, Vol.103 (5), p.715-721

1999

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The bactericidal/permeability-increasing protein (BPI) in antibacterial host defense

What is the real role of antimicrobial polypeptides that can mediate several other inflammatory responses?

The potent anti-Staphylococcus aureus activity of a sterile rabbit inflammatory fluid is due to a 14-kD phospholipase A2

High-affinity binding of the bactericidal/permeability-increasing protein and a recombinant amino-terminal fragment to the lipid A region of lipopolysaccharide

Structural determinants of the action against Escherichia coli of a human inflammatory fluid phospholipase A2 in concert with polymorphonuclear leukocytes

Human bactericidal/permeability-increasing protein and a recombinant NH2-terminal fragment cause killing of serum-resistant Gram-negative bacteria in whole blood and inhibit tumor necrosis factor release induced by the bacteria

Role of the bactericidal/permeability-increasing protein in host defence

Bacterial lipopolysaccharide primes human neutrophils for enhanced release of arachidonic acid and causes phosphorylation of an 85-kD cytosolic phospholipase A2

Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations

Antibacterial 15-kDa protein isoforms (p15s) are members of a novel family of leukocyte proteins

Individual and synergistic effects of rabbit granulocyte proteins on Escherichia coli

Effect of lipopolysaccharide (LPS) chain length on interactions of bactericidal/permeability-increasing protein and its bioactive 23-kilodalton NH2-terminal fragment with isolated LPS and intact Proteus mirabilis and Escherichia coli

A 25-kDa NH2-terminal fragment carries all the antibacterial activities of the human neutrophil 60-kDa bactericidal/permeability-increasing protein

Purification of a cellular (granulocyte) and an extracellular (serum) phospholipase A2 that participate in the destruction of Escherichia coli in a rabbit inflammatory exudate

A recombinant amino terminal fragment of bactericidal/permeability-increasing protein inhibits the induction of leukocyte responses by LPS

Separation of sublethal and lethal effects of the bactericidal/permeability increasing protein on Escherichia coli

[2] Utilization of labeled Escherichia coli as phospholipase substrate

The Carboxyl-terminal Domain of Closely Related Endotoxin-binding Proteins Determines the Target of Protein-Lipopolysaccharide Complexes

Mechanisms of disposal of bacterial lipopolysaccharides by animal hosts

Potent CD14-mediated signalling of human leukocytes by Escherichia coli can be mediated by interaction of whole bacteria and host cells without extensive prior release of endotoxin

An Opsonic Function of the Neutrophil Bactericidal/Permeability-Increasing Protein Depends on Both Its N- and C-Terminal Domains

Separation of sublethal and lethal effects of polymorphonuclear leukocytes on Escherichia coli

Purification and characterization of a potent bactericidal and membrane active protein from the granules of human polymorphonuclear leukocytes

Prospects for use of recombinant BPI in the treatment of gram-negative bacterial infections

Cell-wall determinants of the bactericidal action of group IIA phospholipase A2 against Gram-positive bacteria

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