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A randomized, controlled trial of asoprisnil, a novel selective progesterone receptor modulator, in women with uterine leiomyomata

Fertility and sterility, 2007-06, Vol.87 (6), p.1399-1412

2007

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Conception and pharmacodynamic profile of drospirenone

Steroids, 2003-11, Vol.68 (10), p.891-905

2003

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Role of nonhuman primate models in the discovery and clinical development of selective progesterone receptor modulators (SPRMs)

Reproductive biology and endocrinology, 2006-10, Vol.4 Suppl 1 (S1), p.S8-S8, Article S8

2006

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Selective Progesterone Receptor Modulator Development and Use in the Treatment of Leiomyomata and Endometriosis

Endocrine reviews, 2005-05, Vol.26 (3), p.423-438

2005

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Abstract P3-05-08: Effect of a novel selective progesterone receptor modulator EC312 for menopausal hormone therapy (MHT) in comparison with Bazedoxifene in vitro

Cancer research (Chicago, Ill.), 2015-05, Vol.75 (9_Supplement), p.P3-P3-05-08

2015

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A prodrug design for improved oral absorption and reduced hepatic interaction

Bioorganic & medicinal chemistry, 2017-10, Vol.25 (20), p.5569-5575

2017

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Dissecting Physiological Roles of Estrogen Receptor α and β with Potent Selective Ligands from Structure-Based Design

Molecular endocrinology (Baltimore, Md.), 2004-07, Vol.18 (7), p.1599-1609

2004

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Synthesis and biological evaluation of 11′ imidazolyl antiprogestins and mesoprogestins

Steroids, 2014-12, Vol.92, p.45-55

2014

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Synthesis and biological evaluation of partially fluorinated antiprogestins and mesoprogestins

Steroids, 2013-02, Vol.78 (2), p.255-267

2013

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Structure-based design, synthesis and in vitro characterization of potent 17β-hydroxysteroid dehydrogenase type 1 inhibitors based on 2-substitutions of estrone and D-homo-estrone

Bioorganic & medicinal chemistry letters, 2009-12, Vol.19 (23), p.6740-6744

2009

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Selective Progesterone Receptor Modulators (SPRMs)

Annals of the New York Academy of Sciences, 2002-03, Vol.955 (1), p.373-388

2002

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The effects of 1-month administration of asoprisnil (J867), a selective progesterone receptor modulator, in healthy premenopausal women

Human reproduction (Oxford), 2005-04, Vol.20 (4), p.1090-1099

2005

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Asoprisnil (J867): a selective progesterone receptor modulator for gynecological therapy

Steroids, 2003-11, Vol.68 (10), p.1019-1032

2003

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Selective progesterone receptor modulators (SPRMs): a novel therapeutic concept in endometriosis

Annals of the New York Academy of Sciences, 2002-03, Vol.955 (1), p.373-388

2002

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Inhibitory effects of fluorine-substituted estrogens on the activity of 17beta-hydroxysteroid dehydrogenases

Molecular and cellular endocrinology, 2006-03, Vol.248 (1), p.218-224

2006

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Endocrine pharmacological characterization of progesterone antagonists and progesterone receptor modulators with respect to PR-agonistic and antagonistic activity

Steroids, 2000-10, Vol.65 (10), p.713-723

2000

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Estrone Sulfate Is a Major Source of Local Estrogen Formation in Human Bone

The journal of clinical endocrinology and metabolism, 2004-09, Vol.89 (9), p.4685-4692

2004

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Discovery, Chemistry, and Reproductive Pharmacology of Asoprisnil and Related 11β-Benzaldoxime Substituted Selective Progesterone Receptor Modulators (SPRMs)

Seminars in reproductive medicine, 2005-02, Vol.23 (1), p.58-73

2005

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Selenium Content and Glutathione Peroxidase Activity in the Testis of the Maturing Rat

The Journal of nutrition, 1986-08, Vol.116 (8), p.1442-1447

1986

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Antiproliferative effects of progesterone antagonists and progesterone receptor modulators on the endometrium

Steroids, 2000-10, Vol.65 (10), p.741-751

2000

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Sulfamates of various estrogens are prodrugs with increased systemic and reduced hepatic estrogenicity at oral application

The Journal of steroid biochemistry and molecular biology, 1995-12, Vol.55 (3), p.395-403

1995

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Inhibition of aromatase activity in human placental microsomes by 13-retro-antiprogestins

Steroids, 1995-02, Vol.60 (2), p.234-238

1995

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Evidence for specific selenium target tissues and new biologically important selenoproteins

Biochimica et biophysica acta, 1988-07, Vol.966 (1), p.12-21

1988

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Drospirenone: A novel progestogen with antimineralocorticoid and antiandrogenic activity: Pharmacological characterization in animal models

Contraception (Stoneham), 1995-02, Vol.51 (2), p.99-110

1995

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Selective progesterone receptor modulator development and use in the treatment of leiomyomata and endometriosis: Recent progress in hormone research

Endocrine reviews, 2005, Vol.26 (3), p.423-438

2005

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A randomized, controlled trial of asoprisnil, a novel selective progesterone receptor modulator, in women with uterine leiomyomata

Conception and pharmacodynamic profile of drospirenone

Role of nonhuman primate models in the discovery and clinical development of selective progesterone receptor modulators (SPRMs)

Selective Progesterone Receptor Modulator Development and Use in the Treatment of Leiomyomata and Endometriosis

Abstract P3-05-08: Effect of a novel selective progesterone receptor modulator EC312 for menopausal hormone therapy (MHT) in comparison with Bazedoxifene in vitro

A prodrug design for improved oral absorption and reduced hepatic interaction

Dissecting Physiological Roles of Estrogen Receptor α and β with Potent Selective Ligands from Structure-Based Design

Synthesis and biological evaluation of 11′ imidazolyl antiprogestins and mesoprogestins

Synthesis and biological evaluation of partially fluorinated antiprogestins and mesoprogestins

Structure-based design, synthesis and in vitro characterization of potent 17β-hydroxysteroid dehydrogenase type 1 inhibitors based on 2-substitutions of estrone and D-homo-estrone

Selective Progesterone Receptor Modulators (SPRMs)

The effects of 1-month administration of asoprisnil (J867), a selective progesterone receptor modulator, in healthy premenopausal women

Asoprisnil (J867): a selective progesterone receptor modulator for gynecological therapy

Selective progesterone receptor modulators (SPRMs): a novel therapeutic concept in endometriosis

Inhibitory effects of fluorine-substituted estrogens on the activity of 17beta-hydroxysteroid dehydrogenases

Endocrine pharmacological characterization of progesterone antagonists and progesterone receptor modulators with respect to PR-agonistic and antagonistic activity

Estrone Sulfate Is a Major Source of Local Estrogen Formation in Human Bone

Discovery, Chemistry, and Reproductive Pharmacology of Asoprisnil and Related 11β-Benzaldoxime Substituted Selective Progesterone Receptor Modulators (SPRMs)

Selenium Content and Glutathione Peroxidase Activity in the Testis of the Maturing Rat

Antiproliferative effects of progesterone antagonists and progesterone receptor modulators on the endometrium

Sulfamates of various estrogens are prodrugs with increased systemic and reduced hepatic estrogenicity at oral application

Inhibition of aromatase activity in human placental microsomes by 13-retro-antiprogestins

Evidence for specific selenium target tissues and new biologically important selenoproteins

Drospirenone: A novel progestogen with antimineralocorticoid and antiandrogenic activity: Pharmacological characterization in animal models

Selective progesterone receptor modulator development and use in the treatment of leiomyomata and endometriosis: Recent progress in hormone research

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