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Cascade Reactions in Total Synthesis

Angewandte Chemie International Edition, 2006-11, Vol.45 (43), p.7134-7186

2006

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Total synthesis and antiviral activity of indolosesquiterpenoids from the xiamycin and oridamycin families

Nature communications, 2015-02, Vol.6 (1), p.6096-6096, Article 6096

2015

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Recent Advances in the Chemistry and Biology of Naturally Occurring Antibiotics

Angewandte Chemie International Edition, 2009-01, Vol.48 (4), p.660-719

2009

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Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable

Angewandte Chemie International Edition, 2014-11, Vol.53 (45), p.12059-12063

International ed. in English, 2014

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Asymmetric Total Syntheses of Platensimycin

Angewandte Chemie International Edition, 2007-05, Vol.46 (21), p.3942-3945

2007

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Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13

Nature communications, 2023-08, Vol.14 (1), p.5158-5158, Article 5158

2023

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Predicting the Human Hepatic Clearance of Acidic and Zwitterionic Drugs

Journal of medicinal chemistry, 2020-10, Vol.63 (20), p.11831-11844

2020

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Total Synthesis of Platensimycin and Related Natural Products

Journal of the American Chemical Society, 2009-11, Vol.131 (46), p.16905-16918

2009

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Rhodium-Catalyzed Asymmetric Enyne Cycloisomerization of Terminal Alkynes and Formal Total Synthesis of (-)-Platensimycin

Angewandte Chemie (International ed.), 2009-08, Vol.48 (34), p.6293-6295

2009

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Total Syntheses of (±)-Platencin and (−)-Platencin

Journal of the American Chemical Society, 2009-11, Vol.131 (43), p.15909-15917

2009

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Total Synthesis of Platencin

Angewandte Chemie (International ed.), 2008-02, Vol.47 (9), p.1780-1783

2008

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Adamantaplatensimycin: A Bioactive Analogue of Platensimycin

Angewandte Chemie International Edition, 2007-01, Vol.46 (25), p.4712-4714

2007

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Synthesis and Reactions of the Pestalotiopsin Skeleton

Angewandte Chemie International Edition, 2008-07, Vol.47 (30), p.5631-5633

2008

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Samarium(II)-iodide-mediated cyclizations in natural product synthesis

Chemical reviews, 2004-07, Vol.104 (7), p.3371-3404

2004

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A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide‑1 Receptor

Journal of medicinal chemistry, 2022-06, Vol.65 (12), p.8208-8226

2022

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Total Synthesis of Platensimycin

Angewandte Chemie International Edition, 2006-10, Vol.45 (42), p.7086-7090

2006

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Synthesis of Spiropiperidine Lactam Acetyl-CoA Carboxylase Inhibitors

Journal of organic chemistry, 2012-11, Vol.77 (22), p.10050-10057

2012

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The Remarkable Effect of Cosolvent on a Samarium(II)-Mediated 4-exo-trig Cyclization: Further Synthetic Studies on Pestalotiopsin A

Journal of organic chemistry, 2003-04, Vol.68 (8), p.3190-3198

2003

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6-Azaspiro[2.5]octanes as small molecule agonists of the human glucagon-like peptide-1 receptor

Bioorganic & medicinal chemistry letters, 2023-10, Vol.94, p.129454-129454, Article 129454

2023

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Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting

Journal of medicinal chemistry, 2020-10, Vol.63 (19), p.10879-10896

2020

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Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK)

Journal of medicinal chemistry, 2018-08, Vol.61 (16), p.7273-7288

2018

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Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-Life

ACS medicinal chemistry letters, 2023-10, Vol.14 (10), p.1427-1433

2023

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Design, Synthesis, and Biological Evaluation of Platensimycin Analogues with Varying Degrees of Molecular Complexity

Journal of the American Chemical Society, 2008-10, Vol.130 (39), p.13110-13119

2008

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Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide‑1 Receptor (GLP-1R) Agonists

Journal of medicinal chemistry, 2015-05, Vol.58 (9), p.4080-4085

2015

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Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists

European journal of medicinal chemistry, 2015-10, Vol.103, p.175-184

2015

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Cascade Reactions in Total Synthesis

Total synthesis and antiviral activity of indolosesquiterpenoids from the xiamycin and oridamycin families

Recent Advances in the Chemistry and Biology of Naturally Occurring Antibiotics

Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable

Asymmetric Total Syntheses of Platensimycin

Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13

Predicting the Human Hepatic Clearance of Acidic and Zwitterionic Drugs

Total Synthesis of Platensimycin and Related Natural Products

Rhodium-Catalyzed Asymmetric Enyne Cycloisomerization of Terminal Alkynes and Formal Total Synthesis of (-)-Platensimycin

Total Syntheses of (±)-Platencin and (−)-Platencin

Total Synthesis of Platencin

Adamantaplatensimycin: A Bioactive Analogue of Platensimycin

Synthesis and Reactions of the Pestalotiopsin Skeleton

Samarium(II)-iodide-mediated cyclizations in natural product synthesis

A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide‑1 Receptor

Total Synthesis of Platensimycin

Synthesis of Spiropiperidine Lactam Acetyl-CoA Carboxylase Inhibitors

The Remarkable Effect of Cosolvent on a Samarium(II)-Mediated 4-exo-trig Cyclization: Further Synthetic Studies on Pestalotiopsin A

6-Azaspiro[2.5]octanes as small molecule agonists of the human glucagon-like peptide-1 receptor

Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting

Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK)

Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-Life

Design, Synthesis, and Biological Evaluation of Platensimycin Analogues with Varying Degrees of Molecular Complexity

Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide‑1 Receptor (GLP-1R) Agonists

Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists

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