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Regulation of GPCR signaling in Hypertension

Biochimica et biophysica acta, 2010-12, Vol.1802 (12), p.1268-1275

2010

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G Protein-Coupled Receptor Kinase 2 Ablation in Cardiac Myocytes Before or After Myocardial Infarction Prevents Heart Failure

Circulation research, 2008-08, Vol.103 (4), p.413-422

2008

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Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (34), p.12457-12462

2008

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Level of G protein–Coupled Receptor Kinase-2 Determines Myocardial Ischemia/Reperfusion Injury via Pro- and Anti-Apoptotic Mechanisms

Circulation research, 2010-10, Vol.107 (9), p.1140-1149

2010

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S100A1 Genetically Targeted Therapy Reverses Dysfunction of Human Failing Cardiomyocytes

Journal of the American College of Cardiology, 2011-08, Vol.58 (9), p.966-973

2011

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Adiponectin inhibits vascular endothelial growth factor-induced migration of human coronary artery endothelial cells

Cardiovascular research, 2008-05, Vol.78 (2), p.376-384

2008

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Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy

Journal of molecular and cellular cardiology, 2011-03, Vol.50 (3), p.460-470

2011

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Cardiac S100A1 protein levels determine contractile performance and propensity toward heart failure after myocardial infarction

Circulation (New York, N.Y.), 2006-09, Vol.114 (12), p.1258-1268

2006

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GPCR signalling in hypertension: role of GRKs

Clinical science (1979), 2008-08, Vol.115 (3), p.79

2008

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Targeted Inhibition of Cardiomyocyte Gi Signaling Enhances Susceptibility to Apoptotic Cell Death in Response to Ischemic Stress

Circulation (New York, N.Y.), 2008-03, Vol.117 (11), p.1378-1387

2008

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G Protein Coupling and Second Messenger Generation Are Indispensable for Metalloprotease-dependent, Heparin-binding Epidermal Growth Factor Shedding through Angiotensin II Type-1 Receptor

The Journal of biological chemistry, 2005-07, Vol.280 (28), p.26592-26599

2005

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Darbepoetin alfa, a long-acting erythropoietin analog, offers novel and delayed cardioprotection for the ischemic heart

American journal of physiology. Heart and circulatory physiology, 2007-07, Vol.293 (1), p.H60-H68

2007

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Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism

Journal of inherited metabolic disease, 2015-11, Vol.38 (6), p.1029-1039

2015

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Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure

Nature medicine, 2007-03, Vol.13 (3), p.315-323

2007

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Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia

Proceedings of the National Academy of Sciences - PNAS, 2007-08, Vol.104 (32), p.12988-12993

2007

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Metabolomics as a Key Integrator for "Omic" Advancement of Personalized Medicine and Future Therapies

Clinical and translational science, 2012-06, Vol.5 (3), p.285-288

2012

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Gq-Coupled Receptor Agonists Mediate Cardiac Hypertrophy Via the Vasculature

Hypertension (Dallas, Tex. 1979), 2002-11, Vol.40 (5), p.660-666

2002

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Myocardial gene transfer and overexpression of β2-Adrenergic receptors potentiates the functional recovery of unloaded failing hearts

Circulation (New York, N.Y.), 2002-07, Vol.106 (1), p.124-129

2002

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Mineralocorticoid receptors, corticosteroids and the heart: where do we stand?

Journal of hypertension, 2010-05, Vol.28 (5), p.889-891

Eckhart, Andrea D

2010

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Persistent increases in Ca(2+) influx through Cav1.2 shortens action potential and causes Ca(2+) overload-induced afterdepolarizations and arrhythmias

Basic research in cardiology, 2016-01, Vol.111 (1), p.4-4

2016

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Cardiac adenoviral S100A1 gene delivery rescues failing myocardium

The Journal of clinical investigation, 2004-12, Vol.114 (11), p.1550-1563

2004

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Persistent increases in Ca2+ influx through Cav1.2 shortens action potential and causes Ca2+ overload-induced afterdepolarizations and arrhythmias

Basic research in cardiology, 2016-01, Vol.111 (1), p.4-4, Article 4

2016

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Exploiting functional domains of GRK2/3 to alter the competitive balance of pro‐ and anticontractile signaling in airway smooth muscle

The FASEB journal, 2014-02, Vol.28 (2), p.956-965

2014

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The Inotropic Peptide βARKct Improves βAR Responsiveness in Normal and Failing Cardiomyocytes Through Gβγ-Mediated L-Type Calcium Current Disinhibition

Circulation research, 2011-01, Vol.108 (1), p.27-39

2011

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Beta-adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases

The Journal of biological chemistry, 2002-08, Vol.277 (35), p.32116-32123

2002

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Regulation of GPCR signaling in Hypertension

G Protein-Coupled Receptor Kinase 2 Ablation in Cardiac Myocytes Before or After Myocardial Infarction Prevents Heart Failure

Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes

Level of G protein–Coupled Receptor Kinase-2 Determines Myocardial Ischemia/Reperfusion Injury via Pro- and Anti-Apoptotic Mechanisms

S100A1 Genetically Targeted Therapy Reverses Dysfunction of Human Failing Cardiomyocytes

Adiponectin inhibits vascular endothelial growth factor-induced migration of human coronary artery endothelial cells

Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy

Cardiac S100A1 protein levels determine contractile performance and propensity toward heart failure after myocardial infarction

GPCR signalling in hypertension: role of GRKs

Targeted Inhibition of Cardiomyocyte Gi Signaling Enhances Susceptibility to Apoptotic Cell Death in Response to Ischemic Stress

G Protein Coupling and Second Messenger Generation Are Indispensable for Metalloprotease-dependent, Heparin-binding Epidermal Growth Factor Shedding through Angiotensin II Type-1 Receptor

Darbepoetin alfa, a long-acting erythropoietin analog, offers novel and delayed cardioprotection for the ischemic heart

Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism

Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure

Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia

Metabolomics as a Key Integrator for "Omic" Advancement of Personalized Medicine and Future Therapies

Gq-Coupled Receptor Agonists Mediate Cardiac Hypertrophy Via the Vasculature

Myocardial gene transfer and overexpression of β2-Adrenergic receptors potentiates the functional recovery of unloaded failing hearts

Mineralocorticoid receptors, corticosteroids and the heart: where do we stand?

Persistent increases in Ca(2+) influx through Cav1.2 shortens action potential and causes Ca(2+) overload-induced afterdepolarizations and arrhythmias

Cardiac adenoviral S100A1 gene delivery rescues failing myocardium

Persistent increases in Ca2+ influx through Cav1.2 shortens action potential and causes Ca2+ overload-induced afterdepolarizations and arrhythmias

Exploiting functional domains of GRK2/3 to alter the competitive balance of pro‐ and anticontractile signaling in airway smooth muscle

The Inotropic Peptide βARKct Improves βAR Responsiveness in Normal and Failing Cardiomyocytes Through Gβγ-Mediated L-Type Calcium Current Disinhibition

Beta-adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases

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