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The life of a cell: apoptosis regulation by the PI3K/PKB pathway

Biochemical journal, 2008-11, Vol.415 (3), p.333-344

Duronio, Vincent

2008

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β1 integrin, ILK and mTOR regulate collagen synthesis in mechanically loaded tendon cells

Scientific reports, 2020-07, Vol.10 (1), p.12644-12644, Article 12644

2020

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Exposure to oxLDL impairs TGF-β activity in human tendon cells

BMC musculoskeletal disorders, 2023-03, Vol.24 (1), p.197-197, Article 197

2023

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The N Terminus of the Anti-apoptotic BCL-2 Homologue MCL-1 Regulates Its Localization and Function

The Journal of biological chemistry, 2007-11, Vol.282 (44), p.32233-32242

2007

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Proliferation of Pulmonary Interstitial Fibroblasts Is Mediated by Transforming Growth Factor-β1-induced Release of Extracellular Fibroblast Growth Factor-2 and Phosphorylation of p38 MAPK and JNK

The Journal of biological chemistry, 2005-12, Vol.280 (52), p.43000-43009

2005

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Cyclic strain alters the expression and release of angiogenic factors by human tendon cells

PloS one, 2014-05, Vol.9 (5), p.e97356-e97356

2014

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An essential role for MCL-1 in ATR-mediated CHK1 phosphorylation

Molecular biology of the cell, 2008-08, Vol.19 (8), p.3212-3220

2008

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MCL-1 localizes to sites of DNA damage and regulates DNA damage response

Cell cycle (Georgetown, Tex.), 2010-07, Vol.9 (14), p.2915-2927

2010

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MCL-1 Inhibits BAX in the Absence of MCL-1/BAX Interaction

The Journal of biological chemistry, 2008-03, Vol.283 (10), p.6384-6392

2008

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Excessive Apoptosis in Patellar Tendinopathy in Athletes

The American journal of sports medicine, 2007-04, Vol.35 (4), p.605-611

2007

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Impairing Eukaryotic Elongation Factor 2 Kinase Activity Decreases Atherosclerotic Plaque Formation

Canadian journal of cardiology, 2014-12, Vol.30 (12), p.1684-1688

2014

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Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells

Blood, 2007-09, Vol.110 (6), p.1942-1949

2007

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Dissociation of Cytokine-Induced Phosphorylation of Bad and Activation of PKB/akt: Involvement of MEK Upstream of Bad Phosphorylation

Proceedings of the National Academy of Sciences - PNAS, 1998-06, Vol.95 (13), p.7439-7444

1998

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Ceramide-1-phosphate promotes cell survival through activation of the phosphatidylinositol 3-kinase/protein kinase B pathway

FEBS letters, 2005-07, Vol.579 (17), p.3744-3750

2005

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Identification of a Hematopoietic Cell Dedifferentiation-Inducing Factor

Journal of cellular physiology, 2016-06, Vol.231 (6), p.1350-1363

2016

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Ceramide Inhibits Protein Kinase B/Akt by Promoting Dephosphorylation of Serine 473

The Journal of biological chemistry, 2000-05, Vol.275 (18), p.13330-13335

2000

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LOX-1 augments oxLDL uptake by lysoPC-stimulated murine macrophages but is not required for oxLDL clearance from plasma

Journal of lipid research, 2009-08, Vol.50 (8), p.1676-1684

2009

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Oxidized LDL-mediated macrophage survival involves elongation factor-2 kinase

Arteriosclerosis, thrombosis, and vascular biology, 2009-01, Vol.29 (1), p.92

2009

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TAPP1 and TAPP2 Are Targets of Phosphatidylinositol 3-Kinase Signaling in B Cells: Sustained Plasma Membrane Recruitment Triggered by the B-Cell Antigen Receptor

Molecular and Cellular Biology, 2002-08, Vol.22 (15), p.5479-5491

2002

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SPARC/SFN interaction, suppresses type I collagen in dermal fibroblasts

Journal of cellular biochemistry, 2012-08, Vol.113 (8), p.2622-2632

2012

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The small molecule 2-phenylethynesulfonamide induces covalent modification of p53

Biochemical and biophysical research communications, 2017-01, Vol.482 (1), p.154-158

2017

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Skin cells, but not T cells, are resistant to indoleamine 2, 3-dioxygenase (IDO) expressed by allogeneic fibroblasts

Wound repair and regeneration, 2008-05, Vol.16 (3), p.379-387

2008

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Sphingosine kinase regulates oxidized low density lipoprotein-mediated calcium oscillations and macrophage survival

Journal of lipid research, 2010-05, Vol.51 (5), p.991-998

2010

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Oxidized low density lipoprotein inhibits macrophage apoptosis through activation of the PI 3-kinase/PKB pathway

Journal of lipid research, 2001-09, Vol.42 (9), p.1483-1491

2001

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Identification of a Novel Phosphorylation Site, Ser-170, as a Regulator of Bad Pro-apoptotic Activity

The Journal of biological chemistry, 2002-02, Vol.277 (8), p.6399-6405

2002

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The life of a cell: apoptosis regulation by the PI3K/PKB pathway

β1 integrin, ILK and mTOR regulate collagen synthesis in mechanically loaded tendon cells

Exposure to oxLDL impairs TGF-β activity in human tendon cells

The N Terminus of the Anti-apoptotic BCL-2 Homologue MCL-1 Regulates Its Localization and Function

Proliferation of Pulmonary Interstitial Fibroblasts Is Mediated by Transforming Growth Factor-β1-induced Release of Extracellular Fibroblast Growth Factor-2 and Phosphorylation of p38 MAPK and JNK

Cyclic strain alters the expression and release of angiogenic factors by human tendon cells

An essential role for MCL-1 in ATR-mediated CHK1 phosphorylation

MCL-1 localizes to sites of DNA damage and regulates DNA damage response

MCL-1 Inhibits BAX in the Absence of MCL-1/BAX Interaction

Excessive Apoptosis in Patellar Tendinopathy in Athletes

Impairing Eukaryotic Elongation Factor 2 Kinase Activity Decreases Atherosclerotic Plaque Formation

Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells

Dissociation of Cytokine-Induced Phosphorylation of Bad and Activation of PKB/akt: Involvement of MEK Upstream of Bad Phosphorylation

Ceramide-1-phosphate promotes cell survival through activation of the phosphatidylinositol 3-kinase/protein kinase B pathway

Identification of a Hematopoietic Cell Dedifferentiation-Inducing Factor

Ceramide Inhibits Protein Kinase B/Akt by Promoting Dephosphorylation of Serine 473

LOX-1 augments oxLDL uptake by lysoPC-stimulated murine macrophages but is not required for oxLDL clearance from plasma

Oxidized LDL-mediated macrophage survival involves elongation factor-2 kinase

TAPP1 and TAPP2 Are Targets of Phosphatidylinositol 3-Kinase Signaling in B Cells: Sustained Plasma Membrane Recruitment Triggered by the B-Cell Antigen Receptor

SPARC/SFN interaction, suppresses type I collagen in dermal fibroblasts

The small molecule 2-phenylethynesulfonamide induces covalent modification of p53

Skin cells, but not T cells, are resistant to indoleamine 2, 3-dioxygenase (IDO) expressed by allogeneic fibroblasts

Sphingosine kinase regulates oxidized low density lipoprotein-mediated calcium oscillations and macrophage survival

Oxidized low density lipoprotein inhibits macrophage apoptosis through activation of the PI 3-kinase/PKB pathway

Identification of a Novel Phosphorylation Site, Ser-170, as a Regulator of Bad Pro-apoptotic Activity

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