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Proteoforms feel the heat

Nature chemical biology, 2023-08, Vol.19 (8), p.930-931

2023

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Access to a Structurally Complex Compound Collection via Ring Distortion of the Alkaloid Sinomenine

Organic letters, 2016-10, Vol.18 (19), p.4852-4855

2016

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Predictive compound accumulation rules yield a broad-spectrum antibiotic

Nature (London), 2017-05, Vol.545 (7654), p.299-304

2017

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Proximal Capture Dynamics for a Single Biological Nanopore Sensor

The journal of physical chemistry. B, 2015-08, Vol.119 (33), p.10448-10455

2015

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(ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition

Cell chemical biology, 2018-12, Vol.25 (12), p.1533-1546.e12

2018

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MSModDetector: a tool for detecting mass shifts and post-translational modifications in individual ion mass spectrometry data

Bioinformatics (Oxford, England), 2024-06, Vol.40 (6)

2024

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Mapping the Proteoform Landscape of Five Human Tissues

Journal of proteome research, 2022-05, Vol.21 (5), p.1299-1310

2022

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Monitoring Poly(ADP-ribosyl)glycohydrolase Activity with a Continuous Fluorescent Substrate

Cell chemical biology, 2018-12, Vol.25 (12), p.1562-1570.e19

2018

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Going on offense against the gram-negative defense

Proceedings of the National Academy of Sciences - PNAS, 2018-06, Vol.115 (26), p.6530-6532

2018

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Implementation of permeation rules leads to a FabI inhibitor with activity against Gram-negative pathogens

Nature microbiology, 2020-01, Vol.5 (1), p.67-75

2020

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Mapping the KRAS proteoform landscape in colorectal cancer identifies truncated KRAS4B that decreases MAPK signaling

The Journal of biological chemistry, 2023-01, Vol.299 (1), p.102768-102768, Article 102768

2023

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A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV‑2 Macrodomain

ACS chemical biology, 2023-05, Vol.18 (5), p.1200-1207

2023

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Precise Readout of MEK1 Proteoforms upon MAPK Pathway Modulation by Individual Ion Mass Spectrometry

Analytical chemistry (Washington), 2024-03, Vol.96 (11), p.4455-4462

2024

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Correction to “A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV‑2 Macrodomain”

ACS chemical biology, 2024-04, Vol.19 (4), p.1023-1024

2024

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Compound Uptake into E. coli Can Be Facilitated by N -Alkyl Guanidiniums and Pyridiniums

ACS infectious diseases, 2021-01, Vol.7 (1), p.162-173

2021

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Highly multiplexed, label-free proteoform imaging of tissues by individual ion mass spectrometry

Science advances, 2022-08, Vol.8 (32), p.eabp9929-eabp9929

2022

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The effects of diffusion on an exonuclease/nanopore-based DNA sequencing engine

The Journal of chemical physics, 2012-12, Vol.137 (21), p.214903

2012

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Antibiotic Permeation across the Bacterial Outer Membrane Porin

Biophysical journal, 2018-02, Vol.114 (3), p.226a-226a

2018

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Predictive rules for compound accumulation yield a broad-spectrum antibiotic

Nature (London), 2017-05, Vol.545 (7654), p.299-304

2017

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Genetically Encoded Crosslinking Enables Identification of Multivalent Ubiquitin‐Deubiquitylating Enzyme Interactions

Chembiochem : a European journal of chemical biology, 2023-08, Vol.24 (15), p.e202300305-n/a

2023

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Temporal regulation of gene expression through integration of p53 dynamics and modifications

Science advances, 2024-10, Vol.10 (43), p.eadp2229

2024

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Next-Generation Serology by Mass Spectrometry: Readout of the SARS-CoV‑2 Antibody Repertoire

Journal of proteome research, 2022-01, Vol.21 (1), p.274-288

2022

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Chemical Approaches to Understanding Small-molecule Accumulation in Bacteria and Poly(ADP-ribosyl)ation

Drown, Bryon Shane

2019

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Kinetic Dynamcs in an αHl-Based Nanopore DNA Sequencer

Biophysical journal, 2012-01, Vol.102 (3), p.727a-727a

2012

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Simulating Nanopore Sensor Dynamics Over Long Times Scales

Biophysical journal, 2012-01, Vol.102 (3), p.728a-728a

2012

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Proteoforms feel the heat

Access to a Structurally Complex Compound Collection via Ring Distortion of the Alkaloid Sinomenine

Predictive compound accumulation rules yield a broad-spectrum antibiotic

Proximal Capture Dynamics for a Single Biological Nanopore Sensor

(ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition

MSModDetector: a tool for detecting mass shifts and post-translational modifications in individual ion mass spectrometry data

Mapping the Proteoform Landscape of Five Human Tissues

Monitoring Poly(ADP-ribosyl)glycohydrolase Activity with a Continuous Fluorescent Substrate

Going on offense against the gram-negative defense

Implementation of permeation rules leads to a FabI inhibitor with activity against Gram-negative pathogens

Mapping the KRAS proteoform landscape in colorectal cancer identifies truncated KRAS4B that decreases MAPK signaling

A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV‑2 Macrodomain

Precise Readout of MEK1 Proteoforms upon MAPK Pathway Modulation by Individual Ion Mass Spectrometry

Correction to “A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV‑2 Macrodomain”

Compound Uptake into E. coli Can Be Facilitated by N -Alkyl Guanidiniums and Pyridiniums

Highly multiplexed, label-free proteoform imaging of tissues by individual ion mass spectrometry

The effects of diffusion on an exonuclease/nanopore-based DNA sequencing engine

Antibiotic Permeation across the Bacterial Outer Membrane Porin

Predictive rules for compound accumulation yield a broad-spectrum antibiotic

Genetically Encoded Crosslinking Enables Identification of Multivalent Ubiquitin‐Deubiquitylating Enzyme Interactions

Temporal regulation of gene expression through integration of p53 dynamics and modifications

Next-Generation Serology by Mass Spectrometry: Readout of the SARS-CoV‑2 Antibody Repertoire

Chemical Approaches to Understanding Small-molecule Accumulation in Bacteria and Poly(ADP-ribosyl)ation

Kinetic Dynamcs in an αHl-Based Nanopore DNA Sequencer

Simulating Nanopore Sensor Dynamics Over Long Times Scales

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