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Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions

Cell metabolism, 2016-11, Vol.24 (5), p.740-752

2016

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Mechanism of farnesylated CAAX protein processing by the intramembrane protease Rce1

Nature (London), 2013-12, Vol.504 (7479), p.301-305

2013

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Mechanism of Isoprenylcysteine Carboxyl Methylation from the Crystal Structure of the Integral Membrane Methyltransferase ICMT

Molecular cell, 2011-12, Vol.44 (6), p.997-1004

2011

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TREM2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant

EMBO molecular medicine, 2017-10, Vol.9 (10), p.1366-1378

2017

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A simeprevir-inducible molecular switch for the control of cell and gene therapies

Nature communications, 2023-11, Vol.14 (1), p.7753-7753, Article 7753

2023

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Structural Interactions between Inhibitor and Substrate Docking Sites Give Insight into Mechanisms of Human PS1 Complexes

Structure (London), 2014-01, Vol.22 (1), p.125-135

2014

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An exTREMe disruption in Alzheimer's cleanup

The Journal of biological chemistry, 2018-08, Vol.293 (32), p.12647-12648

Dodd, Roger B.

2018

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Therapeutic Monoclonal Antibodies to Complex Membrane Protein Targets: Antigen Generation and Antibody Discovery Strategies

BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy, 2018-08, Vol.32 (4), p.339-355

2018

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Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation

The Journal of biological chemistry, 2021-01, Vol.296, p.100631, Article 100631

2021

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Solution Structure of the Kaposi's Sarcoma-associated Herpesvirus K3 N-terminal Domain Reveals a Novel E2-binding C4HC3-type RING Domain

The Journal of biological chemistry, 2004-12, Vol.279 (51), p.53840-53847

2004

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Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex

The European respiratory journal, 2023-09, Vol.62 (3), p.2202210

2023

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Robust Prediction of Relative Binding Energies for Protein–Protein Complex Mutations Using Free Energy Perturbation Calculations

Journal of molecular biology, 2024-08, Vol.436 (16), p.168640, Article 168640

2024

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Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules

The EMBO journal, 2006-04, Vol.25 (8), p.1635-1645

2006

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Lectin-like proteins in model organisms: implications for evolution of carbohydrate-binding activity

Glycobiology (Oxford), 2001-05, Vol.11 (5), p.71R-79R

2001

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C-Type lectin-like domains in Caenorhabditis elegans: predictions from the complete genome sequence

Glycobiology (Oxford), 1999-12, Vol.9 (12), p.1357-1369

1999

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Interaction of Mannose-binding Protein with Associated Serine Proteases

The Journal of biological chemistry, 2000-10, Vol.275 (40), p.30962-30969

2000

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Downregulation of cell surface receptors by the K3 family of viral and cellular ubiquitin E3 ligases

Immunological reviews, 2005-10, Vol.207 (1), p.112-125

2005

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Mechanismof farnesylated CAAX protein processing by the intramembrane protease Rce1

Nature (London), 2013-12, Vol.504 (7479), p.301

2013

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Mechanism of farnesylated CAAX protein processing by the integral membrane protease Rce1

Nature (London), 2013-12, Vol.504 (7479)

2013

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TREM 2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant

EMBO molecular medicine, 2017-10, Vol.9 (10), p.1366-1378

2017

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Interaction of mannose-binding protein with associated serine proteases: effects of naturally occurring mutations

The Journal of biological chemistry, 2000-10, Vol.275 (40), p.30962-30969

2000

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Downregulation of cell surface receptors by the K3 family of viral and cellular ubiquitin E3 ligases: Antigen Processing & Presentation

Immunological reviews, 2005, Vol.207, p.112-125

2005

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Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions

Mechanism of farnesylated CAAX protein processing by the intramembrane protease Rce1

Mechanism of Isoprenylcysteine Carboxyl Methylation from the Crystal Structure of the Integral Membrane Methyltransferase ICMT

TREM2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant

A simeprevir-inducible molecular switch for the control of cell and gene therapies

Structural Interactions between Inhibitor and Substrate Docking Sites Give Insight into Mechanisms of Human PS1 Complexes

An exTREMe disruption in Alzheimer's cleanup

ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

Therapeutic Monoclonal Antibodies to Complex Membrane Protein Targets: Antigen Generation and Antibody Discovery Strategies

Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation

Solution Structure of the Kaposi's Sarcoma-associated Herpesvirus K3 N-terminal Domain Reveals a Novel E2-binding C4HC3-type RING Domain

Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex

Robust Prediction of Relative Binding Energies for Protein–Protein Complex Mutations Using Free Energy Perturbation Calculations

Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules

Lectin-like proteins in model organisms: implications for evolution of carbohydrate-binding activity

C-Type lectin-like domains in Caenorhabditis elegans: predictions from the complete genome sequence

Interaction of Mannose-binding Protein with Associated Serine Proteases

Downregulation of cell surface receptors by the K3 family of viral and cellular ubiquitin E3 ligases

Mechanismof farnesylated CAAX protein processing by the intramembrane protease Rce1

Mechanism of farnesylated CAAX protein processing by the integral membrane protease Rce1

TREM 2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant

Interaction of mannose-binding protein with associated serine proteases: effects of naturally occurring mutations

Downregulation of cell surface receptors by the K3 family of viral and cellular ubiquitin E3 ligases: Antigen Processing & Presentation

Prospective risk of stillbirth and neonatal complications in twin pregnancies: systematic review and meta-analysis

Prospective Risk of Stillbirth and Neonatal Complications in Twin Pregnancies: Systematic Review and Meta-analysis

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