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Murine deficiency of peroxisomal l-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis

Cellular and molecular life sciences : CMLS, 2021-07, Vol.78 (14), p.5631-5646

2021

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Peroxisomes can oxidize medium‐ and long‐chain fatty acids through a pathway involving ABCD3 and HSD17B4

The FASEB journal, 2019-03, Vol.33 (3), p.4355-4364

2019

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Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence

Cell reports (Cambridge), 2023-11, Vol.42 (11), p.113371-113371, Article 113371

2023

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Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1

Open biology, 2022-09, Vol.12 (9), p.220179

2022

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A temporal classifier predicts histopathology state and parses acute-chronic phasing in inflammatory bowel disease patients

Communications biology, 2023-01, Vol.6 (1), p.95-12, Article 95

2023

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Identification of Sugct as a modifier locus in the glutaric aciduria type 1 mouse mode

Molecular genetics and metabolism, 2024-04, Vol.141 (4), p.108174, Article 108174

2024

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Bacillus cereus spores release alanine that synergizes with inosine to promote germination

PloS one, 2009-07, Vol.4 (7), p.e6398-e6398

2009

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Crystal Structure of the Actin Binding Domain of the Cyclase-Associated Protein

Biochemistry (Easton), 2004-08, Vol.43 (33), p.10628-10641

2004

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Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets

Gastroenterology (New York, N.Y. 1943), 2022-03, Vol.162 (3), p.828-843.e11

2022

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Glutaric aciduria type 3 is a naturally occurring biochemical trait in inbred mice of 129 substrains

Molecular genetics and metabolism, 2021-02, Vol.132 (2), p.139-145

2021

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DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo

Human molecular genetics, 2020-05, Vol.29 (7), p.1168-1179

2020

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Deletion of 2‐aminoadipic semialdehyde synthase limits metabolite accumulation in cell and mouse models for glutaric aciduria type 1

Journal of inherited metabolic disease, 2020-11, Vol.43 (6), p.1154-1164

2020

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Characterization, Structure, and Inhibition of the Human Succinyl-CoA:glutarate-CoA Transferase, a Putative Genetic Modifier of Glutaric Aciduria Type 1

ACS chemical biology, 2024-07, Vol.19 (7), p.1544-1553

2024

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Leveraging health systems data to characterize a large effect variant conferring risk for liver disease in Puerto Ricans

American journal of human genetics, 2021-11, Vol.108 (11), p.2099-2111

2021

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Acyl-CoA dehydrogenase substrate promiscuity: Challenges and opportunities for development of substrate reduction therapy in disorders of valine and isoleucine metabolism

Journal of inherited metabolic disease, 2023-09, Vol.46 (5), p.931-942

2023

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Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex

ACS chemical biology, 2020-08, Vol.15 (8), p.2041-2047

2020

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Germline deletion of Krüppel-like factor 14 does not increase risk of diet induced metabolic syndrome in male C57BL/6 mice

Biochimica et biophysica acta. Molecular basis of disease, 2017-12, Vol.1863 (12), p.3277-3285

2017

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Design of O-Acetylserine Sulfhydrylase Inhibitors by Mimicking Nature

Journal of medicinal chemistry, 2010-01, Vol.53 (1), p.345-356

2010

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Mild inborn errors of metabolism in commonly used inbred mouse strains

Molecular genetics and metabolism, 2019-04, Vol.126 (4), p.388-396

2019

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Dissecting interactions between nucleosides and germination receptors in Bacillus cereus 569 spores

Microbiology (Society for General Microbiology), 2010-04, Vol.156 (Pt 4), p.1244-1255

2010

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Differential nucleoside recognition during Bacillus cereus 569 (ATCC 10876) spore germination

New journal of chemistry, 2007, Vol.31 (5), p.748-755

2007

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Murine deficiency of peroxisomal l-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis

Peroxisomes can oxidize medium‐ and long‐chain fatty acids through a pathway involving ABCD3 and HSD17B4

Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence

Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1

A temporal classifier predicts histopathology state and parses acute-chronic phasing in inflammatory bowel disease patients

Identification of Sugct as a modifier locus in the glutaric aciduria type 1 mouse mode

Bacillus cereus spores release alanine that synergizes with inosine to promote germination

Crystal Structure of the Actin Binding Domain of the Cyclase-Associated Protein

Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets

Glutaric aciduria type 3 is a naturally occurring biochemical trait in inbred mice of 129 substrains

DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo

Deletion of 2‐aminoadipic semialdehyde synthase limits metabolite accumulation in cell and mouse models for glutaric aciduria type 1

Characterization, Structure, and Inhibition of the Human Succinyl-CoA:glutarate-CoA Transferase, a Putative Genetic Modifier of Glutaric Aciduria Type 1

Leveraging health systems data to characterize a large effect variant conferring risk for liver disease in Puerto Ricans

Acyl-CoA dehydrogenase substrate promiscuity: Challenges and opportunities for development of substrate reduction therapy in disorders of valine and isoleucine metabolism

Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex

Germline deletion of Krüppel-like factor 14 does not increase risk of diet induced metabolic syndrome in male C57BL/6 mice

Design of O-Acetylserine Sulfhydrylase Inhibitors by Mimicking Nature

Mild inborn errors of metabolism in commonly used inbred mouse strains

Dissecting interactions between nucleosides and germination receptors in Bacillus cereus 569 spores

Differential nucleoside recognition during Bacillus cereus 569 (ATCC 10876) spore germination

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