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Nicotinic ACh receptors as therapeutic targets in CNS disorders

Trends in pharmacological sciences (Regular ed.), 2015-02, Vol.36 (2), p.96-108

2015

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Septal Cholinergic Neuromodulation Tunes the Astrocyte-Dependent Gating of Hippocampal NMDA Receptors to Wakefulness

Neuron (Cambridge, Mass.), 2017-05, Vol.94 (4), p.840-854.e7

2017

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Insulin resistance in Alzheimer's disease

Neurobiology of disease, 2014-12, Vol.72, p.92-103

2014

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Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy

Nature communications, 2023-04, Vol.14 (1), p.2367-16, Article 2367

2023

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Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease

Biochemical pharmacology, 2011-10, Vol.82 (8), p.931-942

2011

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Islet amyloid polypeptide (IAPP): a second amyloid in Alzheimer's disease

Current Alzheimer research, 2014-12, Vol.11 (10), p.928-940

2014

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Enhancement of select cognitive domains with rosiglitazone implicates dorsal hippocampus circuitry sensitive to PPARγ agonism in an Alzheimer's mouse model

Brain and behavior, 2021-02, Vol.11 (2), p.e01973-n/a

2021

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VEEV TC-83 Triggers Dysregulation of the Tryptophan-Kynurenine Pathway in the Central Nervous System That Correlates with Cognitive Impairment in Tg2576 Mice

Pathogens (Basel), 2024-05, Vol.13 (5), p.397

2024

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Beta-amyloid peptide--nicotinic acetylcholine receptor interaction: the two faces of health and disease

Frontiers in bioscience, 2007-09, Vol.12 (12), p.5030

Dineley, Kelly T

2007

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Enhanced Leptin Sensitivity, Reduced Adiposity, and Improved Glucose Homeostasis in Mice Lacking Exchange Protein Directly Activated by Cyclic AMP Isoform 1

Molecular and Cellular Biology, 2013-03, Vol.33 (5), p.918-926

2013

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PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease

Experimental neurology, 2017-09, Vol.295, p.1-17

2017

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Heightened cocaine-seeking in male rats associates with a distinct transcriptomic profile in the medial prefrontal cortex

Frontiers in pharmacology, 2022-12, Vol.13, p.1022863

2022

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Divergent Mechanisms for PPARγ Agonism in Ameliorating Aging-Related Versus Cranial Irradiation-Induced Context Discrimination Deficits

Frontiers in aging neuroscience, 2019-03, Vol.11, p.38-38

2019

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Arbovirus infection increases the risk for the development of neurodegenerative disease pathology in the murine model

Brain, behavior, & immunity. Health, 2024-07, Vol.38, p.100780-100780, Article 100780

2024

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Selective induction of calcineurin activity and signaling by oligomeric amyloid beta

Aging cell, 2008-12, Vol.7 (6), p.824-835

2008

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Long-term, West Nile virus-induced neurological changes: A comparison of patients and rodent models

Brain, behavior, & immunity. Health, 2020-08, Vol.7, p.100105-100105, Article 100105

2020

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Collapsin response mediator protein‐2 hyperphosphorylation is an early event in Alzheimer’s disease progression

Journal of neurochemistry, 2007-11, Vol.103 (3), p.1132-1144

2007

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Central Insulin Dysregulation and Energy Dyshomeostasis in Two Mouse Models of Alzheimer’s Disease

Neurobiology of aging, 2017-10, Vol.58, p.1-13

2017

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Neurological Sequelae Resulting from Encephalitic Alphavirus Infection

Frontiers in microbiology, 2016-06, Vol.7, p.959-959

2016

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Spatial and Sex-Dependent Responses of Adult Endogenous Neural Stem Cells to Alcohol Consumption

Stem cell reports, 2017-12, Vol.9 (6), p.1916-1930

2017

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PPARγ recruitment to active ERK during memory consolidation is required for Alzheimer's disease-related cognitive enhancement

The Journal of neuroscience, 2014-03, Vol.34 (11), p.4054-4063

2014

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The A‐Type Potassium Channel Kv4.2 Is a Substrate for the Mitogen‐Activated Protein Kinase ERK

Journal of neurochemistry, 2000-12, Vol.75 (6), p.2277-2287

2000

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Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles

The Journal of neuroscience, 2014-03, Vol.34 (12), p.4260-4272

2014

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Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition

Behavioural brain research, 2009-06, Vol.200 (1), p.95-99

2009

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Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status

Behavioural brain research, 2011-01, Vol.216 (1), p.255-261

2011

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Nicotinic ACh receptors as therapeutic targets in CNS disorders

Septal Cholinergic Neuromodulation Tunes the Astrocyte-Dependent Gating of Hippocampal NMDA Receptors to Wakefulness

Insulin resistance in Alzheimer's disease

Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy

Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease

Islet amyloid polypeptide (IAPP): a second amyloid in Alzheimer's disease

Enhancement of select cognitive domains with rosiglitazone implicates dorsal hippocampus circuitry sensitive to PPARγ agonism in an Alzheimer's mouse model

VEEV TC-83 Triggers Dysregulation of the Tryptophan-Kynurenine Pathway in the Central Nervous System That Correlates with Cognitive Impairment in Tg2576 Mice

Beta-amyloid peptide--nicotinic acetylcholine receptor interaction: the two faces of health and disease

Enhanced Leptin Sensitivity, Reduced Adiposity, and Improved Glucose Homeostasis in Mice Lacking Exchange Protein Directly Activated by Cyclic AMP Isoform 1

PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease

Heightened cocaine-seeking in male rats associates with a distinct transcriptomic profile in the medial prefrontal cortex

Divergent Mechanisms for PPARγ Agonism in Ameliorating Aging-Related Versus Cranial Irradiation-Induced Context Discrimination Deficits

Arbovirus infection increases the risk for the development of neurodegenerative disease pathology in the murine model

Selective induction of calcineurin activity and signaling by oligomeric amyloid beta

Long-term, West Nile virus-induced neurological changes: A comparison of patients and rodent models

Collapsin response mediator protein‐2 hyperphosphorylation is an early event in Alzheimer’s disease progression

Central Insulin Dysregulation and Energy Dyshomeostasis in Two Mouse Models of Alzheimer’s Disease

Neurological Sequelae Resulting from Encephalitic Alphavirus Infection

Spatial and Sex-Dependent Responses of Adult Endogenous Neural Stem Cells to Alcohol Consumption

PPARγ recruitment to active ERK during memory consolidation is required for Alzheimer's disease-related cognitive enhancement

The A‐Type Potassium Channel Kv4.2 Is a Substrate for the Mitogen‐Activated Protein Kinase ERK

Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles

Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition

Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status

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