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Sustained enzymatic activity and flow in crowded protein droplets

Nature communications, 2021-11, Vol.12 (1), p.6293-8, Article 6293

2021

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Evolution of chalcone isomerase from a noncatalytic ancestor

Nature chemical biology, 2018-06, Vol.14 (6), p.548-555

2018

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Pyridoxal 5'-Phosphate-Dependent Enzymes at the Crossroads of Host-Microbe Tryptophan Metabolism

International journal of molecular sciences, 2020-08, Vol.21 (16), p.5823

2020

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New variants of AADC deficiency expand the knowledge of enzymatic phenotypes

Archives of biochemistry and biophysics, 2020-03, Vol.682, p.108263-108263, Article 108263

2020

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Electrostatic interactions drive native‐like aggregation of human alanine:glyoxylate aminostransferase

The FEBS journal, 2017-11, Vol.284 (21), p.3739-3764

2017

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Molecular basis of primary hyperoxaluria: clues to innovative treatments

Urolithiasis, 2019-02, Vol.47 (1), p.67-78

2019

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Non-consecutive enzyme interactions within TCA cycle supramolecular assembly regulate carbon-nitrogen metabolism

Nature communications, 2024-06, Vol.15 (1), p.5285-15, Article 5285

2024

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Author Correction: Non-consecutive enzyme interactions within TCA cycle supramolecular assembly regulate carbon-nitrogen metabolism

Nature communications, 2024-07, Vol.15 (1), p.6196-1, Article 6196

2024

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Non-enzymatic and highly sensitive lactose detection utilizing graphene field-effect transistors

Biosensors & bioelectronics, 2020-10, Vol.165, p.112419-112419, Article 112419

2020

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Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase

Protein science, 2022-05, Vol.31 (5), p.e4303-n/a

2022

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The ILE56 mutation on different genetic backgrounds of alanine:glyoxylate aminotransferase: Clinical features and biochemical characterization

Molecular genetics and metabolism, 2020-09, Vol.131 (1-2), p.171-180

2020

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Biochemical properties and oxalate‐degrading activity of oxalate decarboxylase from bacillus subtilis at neutral pH

IUBMB life, 2019-07, Vol.71 (7), p.917-927

2019

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Enzymes and Liquid-Liquid Phase Separation: A New Era for the Regulation of Enzymatic Activity

Seibutsu Butsuri, 2023, Vol.63(1), pp.12-15

2023

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Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study

Scientific reports, 2023-12, Vol.13 (1), p.22692-22692, Article 22692

2023

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Natural and Unnatural Compounds Rescue Folding Defects of Human Alanine: Glyoxylate Aminotransferase Leading to Primary Hyperoxaluria Type I

Current drug targets, 2016-01, Vol.17 (13), p.1482-1491

2016

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Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for Primary Hyperoxaluria type 1

Biochemical journal, 2019-12, Vol.476 (24), p.3751-3768

2019

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Folding Defects Leading to Primary Hyperoxaluria

Targeting Trafficking in Drug Development, 2018-01, Vol.245, p.313-343

2018

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Editorial: The role of cofactors in protein stability and homeostasis: Focus on human metabolism

Frontiers in molecular biosciences, 2023-01, Vol.10, p.1147451-1147451

2023

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Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T

Biochimie, 2016-12, Vol.131, p.137-148

2016

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Harnessing inter-kingdom metabolic disparities at the human-fungal interface for novel therapeutic approaches

Frontiers in molecular biosciences, 2024-04, Vol.11, p.1386598-1386598

2024

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The Chaperoning Activity of Amino-oxyacetic Acid on Folding-Defective Variants of Human Alanine:Glyoxylate Aminotransferase Causing Primary Hyperoxaluria Type I

ACS chemical biology, 2015-10, Vol.10 (10), p.2227-2236

2015

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Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase

Frontiers in molecular biosciences, 2018-11, Vol.5, p.104-104

2018

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Identification of Human Alanine–Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1

Journal of medicinal chemistry, 2022-07, Vol.65 (14), p.9718-9734

2022

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Biochemical and cellular effects of a novel missense mutation of the AGXT gene associated with Primary Hyperoxaluria Type 1

Biochemical and biophysical research communications, 2023-02, Vol.645, p.118-123

2023

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Molecular Dynamics-Ensemble Docking and Biophysical Studies for Structure-Based Identification of Non-Amino Acidic Ligands of DDAH‑1

Journal of chemical information and modeling, 2024-09, Vol.64 (17), p.6866-6879

2024

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Sustained enzymatic activity and flow in crowded protein droplets

Evolution of chalcone isomerase from a noncatalytic ancestor

Pyridoxal 5'-Phosphate-Dependent Enzymes at the Crossroads of Host-Microbe Tryptophan Metabolism

New variants of AADC deficiency expand the knowledge of enzymatic phenotypes

Electrostatic interactions drive native‐like aggregation of human alanine:glyoxylate aminostransferase

Molecular basis of primary hyperoxaluria: clues to innovative treatments

Non-consecutive enzyme interactions within TCA cycle supramolecular assembly regulate carbon-nitrogen metabolism

Author Correction: Non-consecutive enzyme interactions within TCA cycle supramolecular assembly regulate carbon-nitrogen metabolism

Non-enzymatic and highly sensitive lactose detection utilizing graphene field-effect transistors

Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase

The ILE56 mutation on different genetic backgrounds of alanine:glyoxylate aminotransferase: Clinical features and biochemical characterization

Biochemical properties and oxalate‐degrading activity of oxalate decarboxylase from bacillus subtilis at neutral pH

Enzymes and Liquid-Liquid Phase Separation: A New Era for the Regulation of Enzymatic Activity

Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study

Natural and Unnatural Compounds Rescue Folding Defects of Human Alanine: Glyoxylate Aminotransferase Leading to Primary Hyperoxaluria Type I

Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for Primary Hyperoxaluria type 1

Folding Defects Leading to Primary Hyperoxaluria

Editorial: The role of cofactors in protein stability and homeostasis: Focus on human metabolism

Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T

Harnessing inter-kingdom metabolic disparities at the human-fungal interface for novel therapeutic approaches

The Chaperoning Activity of Amino-oxyacetic Acid on Folding-Defective Variants of Human Alanine:Glyoxylate Aminotransferase Causing Primary Hyperoxaluria Type I

Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase

Identification of Human Alanine–Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1

Biochemical and cellular effects of a novel missense mutation of the AGXT gene associated with Primary Hyperoxaluria Type 1

Molecular Dynamics-Ensemble Docking and Biophysical Studies for Structure-Based Identification of Non-Amino Acidic Ligands of DDAH‑1

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