UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Discovery of a Novel Mode of Protein Kinase Inhibition Characterized by the Mechanism of Inhibition of Human Mesenchymal-epithelial Transition Factor (c-Met) Protein Autophosphorylation by ARQ 197

The Journal of biological chemistry, 2011-06, Vol.286 (23), p.20666-20676

2011

Volltextzugriff (PDF)

ARQ 197, a novel and selective inhibitor of the human c-Met receptor tyrosine kinase with antitumor activity

Molecular cancer therapeutics, 2010-06, Vol.9 (6), p.1544-1553

2010

Volltextzugriff (PDF)

Breast cancer-derived bone metastasis can be effectively reduced through specific c-MET inhibitor tivantinib (ARQ 197) and shRNA c-MET knockdown

Molecular cancer therapeutics, 2012-01, Vol.11 (1), p.214-223

2012

Volltextzugriff (PDF)

Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex

Cancer cell, 2004, Vol.5 (1), p.91-102

2004

Volltextzugriff (PDF)

Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

Cancer cell, 2004-07, Vol.6 (1), p.33-43

2004

Volltextzugriff (PDF)

A novel mode of protein kinase inhibition exploiting hydrophobic motifs of autoinhibited kinases: discovery of ATP-independent inhibitors of fibroblast growth factor receptor

The Journal of biological chemistry, 2011-06, Vol.286 (23), p.20677-20687

2011

Volltextzugriff (PDF)

Structural basis for negative regulation of hypoxia-inducible factor-1α by CITED2

Nature structural & molecular biology, 2003-07, Vol.10 (7), p.504-512

2003

Volltextzugriff (PDF)

Psammaplins from the Sponge Pseudoceratina purpurea: Inhibition of Both Histone Deacetylase and DNA Methyltransferase

Journal of organic chemistry, 2003-05, Vol.68 (10), p.3866-3873

2003

Volltextzugriff (PDF)

Structural and Synthetic Investigations of Tanikolide Dimer, a SIRT2 Selective Inhibitor, and Tanikolide seco-Acid from the Madagascar Marine Cyanobacterium Lyngbya majuscula

Journal of organic chemistry, 2009-08, Vol.74 (15), p.5267-5275

2009

Volltextzugriff (PDF)

Structural and Conformational Requirements for High-Affinity Binding to the SH2 Domain of Grb2

Journal of medicinal chemistry, 1999-03, Vol.42 (6), p.971-980

1999

Volltextzugriff (PDF)

Using a kinase screen to investigate the constituents of the sponge Stelletta clavosa obtained from diverse habitats

Bioorganic & medicinal chemistry, 2004-11, Vol.12 (21), p.5631-5637

2004

Volltextzugriff (PDF)

Biological evaluation of 1-alkyl-3-phenylthioureas as orally active HDL-elevating agents

Bioorganic & medicinal chemistry letters, 2006, Vol.16 (1), p.113-117

2006

Volltextzugriff (PDF)

1-Hydroxyalkyl-3-phenylthioureas as novel HDL-elevating agents

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.809-812

2005

Volltextzugriff (PDF)

Abstract 353: Development of an in vitro screening platform for high capacity evaluation of immunomodulatory drug candidates

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.353-353

2016

Volltextzugriff (PDF)

Abstract 5160: Development of REDX05358, a novel highly selective and potent pan RAF inhibitor and a potential therapeutic for BRAF and RAS mutant tumors

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.5160-5160

2017

Volltextzugriff (PDF)

Oncology drug discovery applications using the FMAT 8100 HTS system

Journal of biomolecular screening, 2003-02, Vol.8 (1), p.81-88

2003

Volltextzugriff (PDF)

Thiourea-based gemfibrozil analogues as HDL-elevating agents

Bioorganic & medicinal chemistry letters, 2002-09, Vol.12 (17), p.2439-2442

2002

Volltextzugriff (PDF)

Abstract 846: Targeted inhibition of c-Met receptor by a selective c-Met inhibitor, Tivantinib, and a specific shRNA reduces breast cancer-derived bone metastases

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.846-846

2012

Volltextzugriff (PDF)

Abstract 3565: Abrogation of the paradoxical activation of the MAPK pathway following RAF inhibition by ARQ 680, a potent inhibitor of the RAF family of serine/threonine kinases

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.3565-3565

2011

Volltextzugriff (PDF)

Abstract 2914: Creation of a novel biochemical and biophysical assay suite to enable the identification of inhibitors targeting inactive kinases

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.2914-2914

2012

Volltextzugriff (PDF)

Abstract 5376: Potentiation of the anti-proliferative and cytotoxic activity of ARQ 197 & gemcitabine with a pulsatile exposure regimen

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.5376-5376

2011

Volltextzugriff (PDF)

DNA Methyl Transferase Inhibiting Halogenated Monoterpenes from the Madagascar Red Marine Alga Portieria hornemannii

Journal of natural products (Washington, D.C.), 2006-04, Vol.69 (4), p.576-579

2006

Volltextzugriff (PDF)

A Novel Mode of Protein Kinase Inhibition Exploiting Hydrophobic Motifs of Autoinhibited Kinases

The Journal of biological chemistry, 2011-12, Vol.286 (23), p.20677-20687

2011

Volltextzugriff (PDF)

1 – 25 von 300

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(226)
Mit Volltextzugriff
(251)

Publikationsform

2 weitere anzeigen...

Weniger anzeigen...

Sprache

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 90 Tagen
(1)

Menü

Weitere Dienste

Einstellungen

Discovery of a Novel Mode of Protein Kinase Inhibition Characterized by the Mechanism of Inhibition of Human Mesenchymal-epithelial Transition Factor (c-Met) Protein Autophosphorylation by ARQ 197

ARQ 197, a novel and selective inhibitor of the human c-Met receptor tyrosine kinase with antitumor activity

Breast cancer-derived bone metastasis can be effectively reduced through specific c-MET inhibitor tivantinib (ARQ 197) and shRNA c-MET knockdown

Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex

Discovery and Optimization of a Series of 3-(3-Phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amines: Orally Bioavailable, Selective, and Potent ATP-Independent Akt Inhibitors

Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

A novel mode of protein kinase inhibition exploiting hydrophobic motifs of autoinhibited kinases: discovery of ATP-independent inhibitors of fibroblast growth factor receptor

Structural basis for negative regulation of hypoxia-inducible factor-1α by CITED2

Psammaplins from the Sponge Pseudoceratina purpurea: Inhibition of Both Histone Deacetylase and DNA Methyltransferase

Structural and Synthetic Investigations of Tanikolide Dimer, a SIRT2 Selective Inhibitor, and Tanikolide seco-Acid from the Madagascar Marine Cyanobacterium Lyngbya majuscula

Structural and Conformational Requirements for High-Affinity Binding to the SH2 Domain of Grb2

Using a kinase screen to investigate the constituents of the sponge Stelletta clavosa obtained from diverse habitats

Biological evaluation of 1-alkyl-3-phenylthioureas as orally active HDL-elevating agents

1-Hydroxyalkyl-3-phenylthioureas as novel HDL-elevating agents

Abstract 353: Development of an in vitro screening platform for high capacity evaluation of immunomodulatory drug candidates

Abstract 5160: Development of REDX05358, a novel highly selective and potent pan RAF inhibitor and a potential therapeutic for BRAF and RAS mutant tumors

Oncology drug discovery applications using the FMAT 8100 HTS system

Thiourea-based gemfibrozil analogues as HDL-elevating agents

Abstract 846: Targeted inhibition of c-Met receptor by a selective c-Met inhibitor, Tivantinib, and a specific shRNA reduces breast cancer-derived bone metastases

Abstract 3565: Abrogation of the paradoxical activation of the MAPK pathway following RAF inhibition by ARQ 680, a potent inhibitor of the RAF family of serine/threonine kinases

Abstract 2914: Creation of a novel biochemical and biophysical assay suite to enable the identification of inhibitors targeting inactive kinases

Abstract 5376: Potentiation of the anti-proliferative and cytotoxic activity of ARQ 197 & gemcitabine with a pulsatile exposure regimen

N-Hydroxy-3-phenyl-2-propenamides as Novel Inhibitors of Human Histone Deacetylase with in Vivo Antitumor Activity: Discovery of (2E)-N-Hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824)

DNA Methyl Transferase Inhibiting Halogenated Monoterpenes from the Madagascar Red Marine Alga Portieria hornemannii

A Novel Mode of Protein Kinase Inhibition Exploiting Hydrophobic Motifs of Autoinhibited Kinases

Suchergebnisse filtern