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Selective Inhibitors of the Mutant B-Raf Pathway: Discovery of a Potent and Orally Bioavailable Aminoisoquinoline

Journal of medicinal chemistry, 2009-10, Vol.52 (20), p.6189-6192

2009

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N-Acylated .alpha.-Amino Acids as Novel Oral Delivery Agents for Proteins

Journal of medicinal chemistry, 1995-10, Vol.38 (21), p.4263-4269

1995

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Discovery of 2-methylpyridine-based biaryl amides as γ-secretase modulators for the treatment of Alzheimer’s disease

Bioorganic & medicinal chemistry letters, 2013-12, Vol.23 (23), p.6447-6454

2013

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Abstract 2681A: Structure-guided design of potent and selective inhibitors of B-Raf kinase displaying on-mechanism in vivo activity

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.2681-2681A

2010

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Substituted 4-anilino-7-phenyl-3-quinolinecarbonitriles as Src kinase inhibitors

Bioorganic & medicinal chemistry letters, 2002-10, Vol.12 (20), p.2989-2992

2002

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8-Anilinoimidazo[4,5- g]quinoline-7-carbonitriles as Src Kinase Inhibitors

Bioorganic & medicinal chemistry letters, 2002-10, Vol.12 (19), p.2761-2765

2002

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Regioselective Synthesis ofa Potent Src Kinase Inhibitor: 4-(2,4-Dichloro-5-methoxyphenylamino)-7-methoxy-8-(2-morpholin-4-ylethoxy)benzo[ g ]quinoline-3-carbonitrile

Synthesis (Stuttgart), 2003-08, Vol.2003 (11), p.1712-1716

2003

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Regioselective Synthesis of a Potent Src Kinase Inhibitor: 4-(2,4-Dichloro-5-methoxyphenylamino)-7-methoxy-8-(2-morpholin-4-ylethoxy)benzo[g]quinoline-3-carbonitrile

Synthesis (Stuttgart), 2003-01, Vol.2003 (11)

2003

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4-[4-[(2-Hydroxybenzoyl)amino]phenyl]butyric Acid as a Novel Oral Delivery Agent for Recombinant Human Growth Hormone

Journal of medicinal chemistry, 1996-06, Vol.39 (13), p.2571-2578

1996

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Microsphere Formation in a Series of Derivatized .alpha.-Amino Acids: Properties, Molecular Modeling, and Oral Delivery of Salmon Calcitonin

Journal of medicinal chemistry, 1995-10, Vol.38 (21), p.4257-4262

1995

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Convenient Preparation of N-Salicyloyl-(L)-phenylalanine

Synthetic communications, 1996-01, Vol.26 (2), p.387-391

1996

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Regioselective Synthesis of a Potent Src Kinase Inhibitor: 4-(2,4-Dichloro-5-methoxyphenylamino)-7-methoxy-8- (2-morpholin-4-ylethoxy)benzo[g]quinoline-3-carbonitrile

ChemInform, 2003-12, Vol.34 (49), p.no-no

2003

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Substituted 4-Anilino-7-phenyl-3-quinolinecarbonitriles as Src Kinase Inhibitors

ChemInform, 2003-02, Vol.34 (8), p.no-no

2003

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8-Anilinoimidazo[4,5-g]quinoline-7-carbonitriles as Src Kinase Inhibitors

ChemInform, 2003-01, Vol.34 (1), p.no-no

2003

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Selective Inhibitors of the Mutant B-Raf Pathway: Discovery of a Potent and Orally Bioavailable Aminoisoquinoline

N-Acylated .alpha.-Amino Acids as Novel Oral Delivery Agents for Proteins

Discovery of 2-methylpyridine-based biaryl amides as γ-secretase modulators for the treatment of Alzheimer’s disease

Abstract 2681A: Structure-guided design of potent and selective inhibitors of B-Raf kinase displaying on-mechanism in vivo activity

Substituted 4-anilino-7-phenyl-3-quinolinecarbonitriles as Src kinase inhibitors

8-Anilinoimidazo[4,5- g]quinoline-7-carbonitriles as Src Kinase Inhibitors

Regioselective Synthesis ofa Potent Src Kinase Inhibitor: 4-(2,4-Dichloro-5-methoxyphenylamino)-7-methoxy-8-(2-morpholin-4-ylethoxy)benzo[ g ]quinoline-3-carbonitrile

Regioselective Synthesis of a Potent Src Kinase Inhibitor: 4-(2,4-Dichloro-5-methoxyphenylamino)-7-methoxy-8-(2-morpholin-4-ylethoxy)benzo[g]quinoline-3-carbonitrile

4-[4-[(2-Hydroxybenzoyl)amino]phenyl]butyric Acid as a Novel Oral Delivery Agent for Recombinant Human Growth Hormone

Microsphere Formation in a Series of Derivatized .alpha.-Amino Acids: Properties, Molecular Modeling, and Oral Delivery of Salmon Calcitonin

Convenient Preparation of N-Salicyloyl-(L)-phenylalanine

Regioselective Synthesis of a Potent Src Kinase Inhibitor: 4-(2,4-Dichloro-5-methoxyphenylamino)-7-methoxy-8- (2-morpholin-4-ylethoxy)benzo[g]quinoline-3-carbonitrile

Substituted 4-Anilino-7-phenyl-3-quinolinecarbonitriles as Src Kinase Inhibitors

8-Anilinoimidazo[4,5-g]quinoline-7-carbonitriles as Src Kinase Inhibitors

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