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Clinically Relevant Concentrations of Anticancer Drugs: A Guide for Nonclinical Studies

Clinical cancer research, 2017-07, Vol.23 (14), p.3489-3498

2017

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Lower diastolic tension may be indicative of higher proarrhythmic propensity in failing human cardiomyocytes

Scientific reports, 2024-07, Vol.14 (1), p.17351-13, Article 17351

2024

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Publisher Correction: Lower diastolic tension may be indicative of higher proarrhythmic propensity in failing human cardiomyocytes

Scientific reports, 2024-08, Vol.14 (1), p.19921-3, Article 19921

2024

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Microphysiological lung models to evaluate the safety of new pharmaceutical modalities: a biopharmaceutical perspective

Lab on a chip, 2019-09, Vol.19 (19), p.3152-3161

2019

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Utilizing targeted cancer therapeutic agents in combination: novel approaches and urgent requirements

Nature reviews. Drug discovery, 2010-11, Vol.9 (11), p.843-856

2010

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Cancer treatment-related cardiotoxicity: current state of knowledge and future research priorities

JNCI : Journal of the National Cancer Institute, 2014-09, Vol.106 (9), p.1

2014

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Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium

Nature biotechnology, 2010-05, Vol.28 (5), p.455-462

2010

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Examining the protective role of ErbB2 modulation in human-induced pluripotent stem cell-derived cardiomyocytes

Toxicological sciences, 2014-10, Vol.141 (2), p.547-559

2014

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Multiparametric Image Analysis of Rat Dorsal Root Ganglion Cultures to Evaluate Peripheral Neuropathy-Inducing Chemotherapeutics

Toxicological sciences, 2017-03, p.kfw254

2017

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Multi-parametric assessment of cardiomyocyte excitation-contraction coupling using impedance and field potential recording: A tool for cardiac safety assessment

Journal of pharmacological and toxicological methods, 2016-09, Vol.81, p.201-216

2016

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Discovery of Potent Myeloid Cell Leukemia‑1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer

Journal of medicinal chemistry, 2019-04, Vol.62 (8), p.3971-3988

2019

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Comparative Uterotrophic Effects of Endoxifen and Tamoxifen in Ovariectomized Sprague-Dawley Rats

Toxicologic pathology, 2014-12, Vol.42 (8), p.1188-1196

2014

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Characterization of acute biliary hyperplasia in Fisher 344 Rats administered the Indole-3-Carbinol Analog, NSC-743380

Toxicology and applied pharmacology, 2014-12, Vol.281 (3), p.303-309

2014

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Toxicology Modernization: Misnomer or Momentum

Medicinal chemistry research, 2023-07, Vol.32 (7), p.1235-1238

2023

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The Evolving Design of NIH-Funded Cardio-Oncology Studies to Address Cancer Treatment-Related Cardiovascular Toxicity

JACC CardioOncology, 2019-09, Vol.1 (1), p.105-113

2019

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Identification and Elucidation of the Biology of Adverse Events: The Challenges of Safety Assessment and Translational Medicine

Clinical cancer research, 2011-11, Vol.17 (21), p.6641-6645

2011

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Hepatic Gene Expression Changes in Mice Associated with Prolonged Sublethal Microcystin Exposure

Toxicologic pathology, 2007-06, Vol.35 (4), p.594-605

2007

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Angiogenic inhibition mediated by a DNAzyme that targets vascular endothelial growth factor receptor 2

Cancer research (Chicago, Ill.), 2002-10, Vol.62 (19), p.5463-5469

2002

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Qualification of Cardiac Troponin I Concentration in Mouse Serum Using Isoproterenol and Implementation in Pharmacology Studies to Accelerate Drug Development

Toxicologic pathology, 2009-08, Vol.37 (5), p.617-628

2009

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An integrated approach for early in vitro seizure prediction utilizing hiPSC neurons and human ion channel assays

Toxicological sciences, 2023-10, Vol.196 (1), p.126-140

2023

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Role of Mcl-1 in regulation of cell death in human induced pluripotent stem cell-derived cardiomyocytes in vitro

Toxicology and applied pharmacology, 2018-12, Vol.360, p.88-98

2018

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Chronic Microcystin Exposure Induces Hepatocyte Proliferation with Increased Expression of Mitotic and Cyclin-associated Genes in P53-deficient Mice

Toxicologic pathology, 2008-02, Vol.36 (2), p.190-203

2008

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Proteomic analysis of rat liver phosphoproteins after treatment with protein kinase inhibitor H89 (N-(2-[p-bromocinnamylamino-]ethyl)-5-isoquinolinesulfonamide)

The Journal of pharmacology and experimental therapeutics, 2006-08, Vol.318 (2), p.589-595

2006

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Remembering Benjamin Franklin Trump

Veterinary pathology, 2008-09, Vol.45 (5), p.611-612

2008

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Making Mechanistic Connections between Cell Signaling Pathways and Pathological Endpoints

Toxicologic pathology, 2004-03, Vol.32 (1_suppl), p.131-135

Davis, Myrtle A.

2004

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Clinically Relevant Concentrations of Anticancer Drugs: A Guide for Nonclinical Studies

Lower diastolic tension may be indicative of higher proarrhythmic propensity in failing human cardiomyocytes

Publisher Correction: Lower diastolic tension may be indicative of higher proarrhythmic propensity in failing human cardiomyocytes

Microphysiological lung models to evaluate the safety of new pharmaceutical modalities: a biopharmaceutical perspective

Utilizing targeted cancer therapeutic agents in combination: novel approaches and urgent requirements

Cancer treatment-related cardiotoxicity: current state of knowledge and future research priorities

Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium

Examining the protective role of ErbB2 modulation in human-induced pluripotent stem cell-derived cardiomyocytes

Multiparametric Image Analysis of Rat Dorsal Root Ganglion Cultures to Evaluate Peripheral Neuropathy-Inducing Chemotherapeutics

Multi-parametric assessment of cardiomyocyte excitation-contraction coupling using impedance and field potential recording: A tool for cardiac safety assessment

Discovery of Potent Myeloid Cell Leukemia‑1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer

Comparative Uterotrophic Effects of Endoxifen and Tamoxifen in Ovariectomized Sprague-Dawley Rats

Characterization of acute biliary hyperplasia in Fisher 344 Rats administered the Indole-3-Carbinol Analog, NSC-743380

Toxicology Modernization: Misnomer or Momentum

The Evolving Design of NIH-Funded Cardio-Oncology Studies to Address Cancer Treatment-Related Cardiovascular Toxicity

Identification and Elucidation of the Biology of Adverse Events: The Challenges of Safety Assessment and Translational Medicine

Hepatic Gene Expression Changes in Mice Associated with Prolonged Sublethal Microcystin Exposure

Angiogenic inhibition mediated by a DNAzyme that targets vascular endothelial growth factor receptor 2

Qualification of Cardiac Troponin I Concentration in Mouse Serum Using Isoproterenol and Implementation in Pharmacology Studies to Accelerate Drug Development

An integrated approach for early in vitro seizure prediction utilizing hiPSC neurons and human ion channel assays

Role of Mcl-1 in regulation of cell death in human induced pluripotent stem cell-derived cardiomyocytes in vitro

Chronic Microcystin Exposure Induces Hepatocyte Proliferation with Increased Expression of Mitotic and Cyclin-associated Genes in P53-deficient Mice

Proteomic analysis of rat liver phosphoproteins after treatment with protein kinase inhibitor H89 (N-(2-[p-bromocinnamylamino-]ethyl)-5-isoquinolinesulfonamide)

Remembering Benjamin Franklin Trump

Making Mechanistic Connections between Cell Signaling Pathways and Pathological Endpoints

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