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Single-cell genomic approaches for developing the next generation of immunotherapies

Nature medicine, 2020-02, Vol.26 (2), p.171-177

2020

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Next Generation CD40 Agonistic Antibodies for Cancer Immunotherapy

Frontiers in immunology, 2022-07, Vol.13, p.940674-940674

2022

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Signaling by Antibodies: Recent Progress

Annual review of immunology, 2017-04, Vol.35 (1), p.285-311

2017

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Human antibodies targeting a Mycobacterium transporter protein mediate protection against tuberculosis

Nature communications, 2021-01, Vol.12 (1), p.602-602, Article 602

2021

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Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis

Cell reports (Cambridge), 2016-05, Vol.15 (9), p.2000-2011

2016

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Anti-SARS-CoV-2 antibodies elicited by COVID-19 mRNA vaccine exhibit a unique glycosylation pattern

Cell reports (Cambridge), 2021-12, Vol.37 (11), p.110114-110114, Article 110114

2021

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BCR affinity differentially regulates colonization of the subepithelial dome and infiltration into germinal centers within Peyer's patches

Nature immunology, 2019-04, Vol.20 (4), p.482-492

2019

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Protocol for assessing murine cell doublet engagement and subsequent effects using flow cytometry and imaging flow cytometry

STAR protocols, 2024-12, Vol.5 (4), p.103152, Article 103152

2024

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Co-targeting of Adenosine Signaling Pathways for Immunotherapy: Potentiation by Fc Receptor Engagement

Cancer cell, 2016-09, Vol.30 (3), p.369-371

2016

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Unified platform for genetic and serological detection of COVID-19 with single-molecule technology

PloS one, 2021-07, Vol.16 (7), p.e0255096-e0255096

2021

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HLA-DRα1 constructs block CD74 expression and MIF effects in experimental autoimmune encephalomyelitis

The Journal of immunology (1950), 2014-05, Vol.192 (9), p.4164-4173

2014

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Creating the next generation of antibodies for I–O

Immuno Oncology Insights, 2023-04, Vol.4 (3), p.55-60

Dahan, Rony

2023

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Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism

Science advances, 2022-02, Vol.8 (8), p.eabm4552-eabm4552

2022

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T-cell-receptor-like antibodies – generation, function and applications

Expert reviews in molecular medicine, 2012-02, Vol.14, p.e6-e6, Article e6

2012

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Toxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunity

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (43), p.11048-11053

2018

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FcγRs Modulate the Anti-tumor Activity of Antibodies Targeting the PD-1/PD-L1 Axis

Cancer cell, 2015-09, Vol.28 (3), p.285-295

2015

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Type I and type II Fc receptors regulate innate and adaptive immunity

Nature immunology, 2014-08, Vol.15 (8), p.707-716

2014

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Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement

Cancer cell, 2016-06, Vol.29 (6), p.820-831

2016

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Bispecific dendritic-T cell engager potentiates anti-tumor immunity

Cell, 2024-01, Vol.187 (2), p.375-389.e18

2024

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Bispecific antibodies increase the therapeutic window of CD40 agonists through selective dendritic cell targeting

Nature cancer, 2022-03, Vol.3 (3), p.287-302

2022

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Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism

Biophysical journal, 2022-02, Vol.121 (3), p.83a-83a

2022

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Abstract B014: Improved therapeutic activity of agonistic, human anti-CD40 monoclonal Abs by selective Fc receptor-engagement

Cancer immunology research, 2016-11, Vol.4 (11_Supplement), p.B014-B014

2016

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Artificial Antigen Presenting Cells for Detection and Desensitization of Autoreactive T cells Associated with Type 1 Diabetes

Nano letters, 2022-06, Vol.22 (11), p.4376-4382

2022

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Therapeutic activity of agonistic, human anti-CD40 monoclonal Abs requires selective FcγR-engagement

Cancer cell, 2016-06, Vol.29 (6), p.820-831

2016

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Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy

Science immunology, 2023-03, Vol.8 (81), p.eadd8005

2023

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Single-cell genomic approaches for developing the next generation of immunotherapies

Next Generation CD40 Agonistic Antibodies for Cancer Immunotherapy

Signaling by Antibodies: Recent Progress

Human antibodies targeting a Mycobacterium transporter protein mediate protection against tuberculosis

Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis

Anti-SARS-CoV-2 antibodies elicited by COVID-19 mRNA vaccine exhibit a unique glycosylation pattern

BCR affinity differentially regulates colonization of the subepithelial dome and infiltration into germinal centers within Peyer's patches

Protocol for assessing murine cell doublet engagement and subsequent effects using flow cytometry and imaging flow cytometry

Co-targeting of Adenosine Signaling Pathways for Immunotherapy: Potentiation by Fc Receptor Engagement

Unified platform for genetic and serological detection of COVID-19 with single-molecule technology

HLA-DRα1 constructs block CD74 expression and MIF effects in experimental autoimmune encephalomyelitis

Creating the next generation of antibodies for I–O

Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism

T-cell-receptor-like antibodies – generation, function and applications

Toxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunity

FcγRs Modulate the Anti-tumor Activity of Antibodies Targeting the PD-1/PD-L1 Axis

Type I and type II Fc receptors regulate innate and adaptive immunity

Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement

Bispecific dendritic-T cell engager potentiates anti-tumor immunity

Bispecific antibodies increase the therapeutic window of CD40 agonists through selective dendritic cell targeting

Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism

Abstract B014: Improved therapeutic activity of agonistic, human anti-CD40 monoclonal Abs by selective Fc receptor-engagement

Artificial Antigen Presenting Cells for Detection and Desensitization of Autoreactive T cells Associated with Type 1 Diabetes

Therapeutic activity of agonistic, human anti-CD40 monoclonal Abs requires selective FcγR-engagement

Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy

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