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Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator

Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (19), p.7910-7915

2013

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The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture

The Journal of biological chemistry, 2006-02, Vol.281 (7), p.3793-3799

2006

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Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

Science (American Association for the Advancement of Science), 1995-07, Vol.269 (5223), p.546-549

1995

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Identification and expression cloning of a leptin receptor, OB-R

Cell, 1995-12, Vol.83 (7), p.1263-1271

1995

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Discovery and optimization of novel, non-steroidal glucocorticoid receptor modulators

Bioorganic & medicinal chemistry letters, 2007-09, Vol.17 (17), p.4901-4905

2007

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Role of IFN-gamma in the Inhibition of the Allergic Airway Inflammation Caused by IL-12

American journal of respiratory cell and molecular biology, 1997-12, Vol.17 (6), p.767-771

1997

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Abstract 5137: Parallel approaches to the discovery of novel BRD4 inhibitors

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.5137-5137

2014

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Ligand-independent Dimerization of the Extracellular Domain of the Leptin Receptor and Determination of the Stoichiometry of Leptin Binding

The Journal of biological chemistry, 1997-07, Vol.272 (29), p.18304-18310

1997

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Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479

Bioorganic & medicinal chemistry letters, 2007-05, Vol.17 (9), p.2570-2576

2007

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1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (4), p.1312-1317

2008

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Leptin receptor (OB-R) signaling: cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

The Journal of biological chemistry, 1997-02, Vol.272 (7), p.4065-4071

1997

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Leptin Receptor (OB-R) Signaling

The Journal of biological chemistry, 1997-02, Vol.272 (7), p.4065-4071

1997

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64 The discovery of leptin and the leptin receptor: Perspectives for the treatment of obesity and wasting disorders

Atherosclerosis, 1997-05, Vol.130, p.S17-S17

Devos, Rene

1997

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Comparison of R128Q Mutations in Human, Ovine, and Chicken Leptins

General and comparative endocrinology, 2002-03, Vol.126 (1), p.52-58

2002

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A human leptin mutant induces weight gain in normal mice

FEBS letters, 1997-03, Vol.405 (2), p.237-240

1997

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OB protein binds specifically to the choroid plexus of mice and rats

Proceedings of the National Academy of Sciences - PNAS, 1996-05, Vol.93 (11), p.5668-5673

1996

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High-level expression of human interferon gamma in Escherichia coli under control of the pL promoter of bacteriophage lambda

Gene, 1984-04, Vol.28 (1), p.55-64

1984

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2-Benzenesulfonyl-8a-benzyl-hexahydro-2H-isoquinolin-6-ones as selective glucocorticoid receptor antagonists

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (20), p.5704-5708

2007

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1 H-Pyrazolo[3,4- g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (4), p.1312-1317

2008

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Interferon-gamma induced clearance of an HCV subgenomic replicon: A role for nitric oxide?

Gastroenterology (New York, N.Y. 1943), 2001-04, Vol.120 (5), p.A555-A555

2001

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ESM-1 Is a Novel Human Endothelial Cell-specific Molecule Expressed in Lung and Regulated by Cytokines

The Journal of biological chemistry, 1996-08, Vol.271 (34), p.20458-20464

1996

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Use of the HCV subgenomic replicon for the selection and characterisation of variants with reduced susceptibility to interferon alfa-2a

Gastroenterology (New York, N.Y. 1943), 2001-04, Vol.120 (5), p.A555-A555

2001

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Establishment and application of bicistronic classical swine fever virus genomes for foreign gene expression and complementation of E2 deletion mutants

Virus research, 2002-05, Vol.85 (2), p.173-185

2002

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A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF

Cell, 1991-09, Vol.66 (6), p.1175-1184

1991

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Structural studies of the carbohydrate chains of human γ‐interferon

European journal of biochemistry, 1986-05, Vol.156 (3), p.651-654

1986

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Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator

The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

Identification and expression cloning of a leptin receptor, OB-R

Discovery and optimization of novel, non-steroidal glucocorticoid receptor modulators

Role of IFN-gamma in the Inhibition of the Allergic Airway Inflammation Caused by IL-12

Abstract 5137: Parallel approaches to the discovery of novel BRD4 inhibitors

Ligand-independent Dimerization of the Extracellular Domain of the Leptin Receptor and Determination of the Stoichiometry of Leptin Binding

Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479

1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity

Leptin receptor (OB-R) signaling: cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

Leptin Receptor (OB-R) Signaling

64 The discovery of leptin and the leptin receptor: Perspectives for the treatment of obesity and wasting disorders

Comparison of R128Q Mutations in Human, Ovine, and Chicken Leptins

A human leptin mutant induces weight gain in normal mice

OB protein binds specifically to the choroid plexus of mice and rats

High-level expression of human interferon gamma in Escherichia coli under control of the pL promoter of bacteriophage lambda

2-Benzenesulfonyl-8a-benzyl-hexahydro-2H-isoquinolin-6-ones as selective glucocorticoid receptor antagonists

1 H-Pyrazolo[3,4- g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity

Interferon-gamma induced clearance of an HCV subgenomic replicon: A role for nitric oxide?

ESM-1 Is a Novel Human Endothelial Cell-specific Molecule Expressed in Lung and Regulated by Cytokines

Use of the HCV subgenomic replicon for the selection and characterisation of variants with reduced susceptibility to interferon alfa-2a

Establishment and application of bicistronic classical swine fever virus genomes for foreign gene expression and complementation of E2 deletion mutants

A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF

Structural studies of the carbohydrate chains of human γ‐interferon

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