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Release and uptake of pathologic alpha-synuclein

Cell and tissue research, 2018-07, Vol.373 (1), p.175-182

2018

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Exosomal cell-to-cell transmission of alpha synuclein oligomers

Molecular neurodegeneration, 2012-08, Vol.7 (1), p.42-42, Article 42

2012

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TDP-43 is intercellularly transmitted across axon terminals

The Journal of cell biology, 2015-11, Vol.211 (4), p.897-911

2015

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Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation

PLoS genetics, 2014-11, Vol.10 (11), p.e1004741

2014

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Inflammatory dysregulation of blood monocytes in Parkinson’s disease patients

Acta neuropathologica, 2014-11, Vol.128 (5), p.651-663

2014

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Stress induced TDP-43 mobility loss independent of stress granules

Nature communications, 2022-09, Vol.13 (1), p.5480-5480, Article 5480

2022

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Proteasome impairment by α-synuclein

PloS one, 2017-09, Vol.12 (9), p.e0184040-e0184040

2017

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T-cell dysregulation is associated with disease severity in Parkinson's Disease

Journal of neuroinflammation, 2021-10, Vol.18 (1), p.250-250, Article 250

2021

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Peripheral monocytes are functionally altered and invade the CNS in ALS patients

Acta neuropathologica, 2016-09, Vol.132 (3), p.391-411

2016

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Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice

The Journal of experimental medicine, 2019-02, Vol.216 (2), p.267-278

2019

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Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients

Scientific reports, 2023-07, Vol.13 (1), p.12019-12019, Article 12019

2023

Volltextzugriff (PDF)

The Role of Lipids in the Initiation of α-Synuclein Misfolding

Frontiers in cell and developmental biology, 2020-09, Vol.8, p.562241-562241

2020

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Thoracic trauma promotes alpha-Synuclein oligomerization in murine Parkinson's disease

Neurobiology of disease, 2022-11, Vol.174, p.105877-105877, Article 105877

2022

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Intracellular Alpha-Synuclein and Immune Cell Function

Frontiers in cell and developmental biology, 2020-10, Vol.8, p.562692

2020

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Low T-cell reactivity to TDP-43 peptides in ALS

Frontiers in immunology, 2023-07, Vol.14, p.1193507-1193507

2023

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Mitochondrial genome study in blood of maternally inherited ALS cases

Human genomics, 2023-07, Vol.17 (1), p.70-70, Article 70

2023

Volltextzugriff (PDF)

Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson's disease and dementia with Lewy bodies

Brain (London, England : 1878), 2016-02, Vol.139 (Pt 2), p.481-494

2016

Volltextzugriff (PDF)

ALS-causing mutations differentially affect PGC-1α expression and function in the brain vs. peripheral tissues

Neurobiology of disease, 2017-01, Vol.97 (Pt A), p.36-45

2017

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Chronic treatment with novel small molecule Hsp90 inhibitors rescues striatal dopamine levels but not α-synuclein-induced neuronal cell loss

PloS one, 2014, Vol.9 (1), p.e86048-e86048

2014

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CHCHD10 mutations p.R15L and p.G66V cause motoneuron disease by haploinsufficiency

Human molecular genetics, 2018-02, Vol.27 (4), p.706-715

2018

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In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer Species

Cell reports (Cambridge), 2019-11, Vol.29 (9), p.2862-2874.e9

2019

Volltextzugriff (PDF)

The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1)

PloS one, 2015-06, Vol.10 (6), p.e0129047-e0129047

2015

Volltextzugriff (PDF)

Increased Immune Activation by Pathologic α‐Synuclein in Parkinson's Disease

Annals of neurology, 2019-10, Vol.86 (4), p.593-606

2019

Volltextzugriff (PDF)

Spreading of alpha-synuclein between different cell types

Behavioural brain research, 2023-01, Vol.436, p.114059-114059, Article 114059

2023

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Protein Binding Partners of Dysregulated miRNAs in Parkinson's Disease Serum

Cells (Basel, Switzerland), 2021-04, Vol.10 (4), p.791

2021

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Release and uptake of pathologic alpha-synuclein

Exosomal cell-to-cell transmission of alpha synuclein oligomers

TDP-43 is intercellularly transmitted across axon terminals

Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation

Inflammatory dysregulation of blood monocytes in Parkinson’s disease patients

Stress induced TDP-43 mobility loss independent of stress granules

Proteasome impairment by α-synuclein

T-cell dysregulation is associated with disease severity in Parkinson's Disease

Peripheral monocytes are functionally altered and invade the CNS in ALS patients

Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice

Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients

The Role of Lipids in the Initiation of α-Synuclein Misfolding

Thoracic trauma promotes alpha-Synuclein oligomerization in murine Parkinson's disease

Intracellular Alpha-Synuclein and Immune Cell Function

Low T-cell reactivity to TDP-43 peptides in ALS

Mitochondrial genome study in blood of maternally inherited ALS cases

Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson's disease and dementia with Lewy bodies

ALS-causing mutations differentially affect PGC-1α expression and function in the brain vs. peripheral tissues

Chronic treatment with novel small molecule Hsp90 inhibitors rescues striatal dopamine levels but not α-synuclein-induced neuronal cell loss

CHCHD10 mutations p.R15L and p.G66V cause motoneuron disease by haploinsufficiency

In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer Species

The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1)

Increased Immune Activation by Pathologic α‐Synuclein in Parkinson's Disease

Spreading of alpha-synuclein between different cell types

Protein Binding Partners of Dysregulated miRNAs in Parkinson's Disease Serum

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