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Plasminogen activation and cancer

Thrombosis and haemostasis, 2005-04, Vol.93 (4), p.676-681

2005

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Reduced metastasis of transgenic mammary cancer in urokinase‐deficient mice

International journal of cancer, 2005-02, Vol.113 (4), p.525-532

2005

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Peptide-Derived Antagonists of the Urokinase Receptor. Affinity Maturation by Combinatorial Chemistry, Identification of Functional Epitopes, and Inhibitory Effect on Cancer Cell Intravasation

Biochemistry (Easton), 2001-10, Vol.40 (40), p.12157-12168

2001

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Cancer invasion and tissue remodeling: common themes in proteolytic matrix degradation

Current opinion in cell biology, 1998-10, Vol.10 (5), p.667-671

1998

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uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion

The Journal of cell biology, 2003-03, Vol.160 (7), p.1009-1015

2003

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Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways

Development (Cambridge), 1996-01, Vol.122 (1), p.181-193

1996

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A functional overlap of plasminogen and MMPs regulates vascularization during placental development

Development (Cambridge), 2003-09, Vol.130 (18), p.4439-4450

2003

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Prognostic and predictive value of intact and cleaved forms of the urokinase plasminogen activator receptor in metastatic prostate cancer

The Prostate, 2011-06, Vol.71 (8), p.899-907

2011

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Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor

Biochemical journal, 2004-06, Vol.380 (Pt 3), p.845-857

2004

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Two distinct expression patterns of urokinase, urokinase receptor and plasminogen activator inhibitor‐1 in colon cancer liver metastases

International journal of cancer, 2009-04, Vol.124 (8), p.1860-1870

2009

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Stromal cells associated with early invasive foci in human mammary ductal carcinoma in situ coexpress urokinase and urokinase receptor

International journal of cancer, 2007-05, Vol.120 (10), p.2086-2095

2007

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MMP-9 Is Differentially Expressed in Primary Human Colorectal Adenocarcinomas and Their Metastases

Molecular cancer research, 2006-05, Vol.4 (5), p.293-302

2006

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The plasminogen fibrinolytic pathway is required for hematopoietic regeneration

Cell stem cell, 2007-12, Vol.1 (6), p.658-670

2007

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Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice

The EMBO journal, 2006-06, Vol.25 (12), p.2686-2697

2006

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Lactational competence and involution of the mouse mammary gland require plasminogen

Development (Cambridge), 2000-10, Vol.127 (20), p.4481-4492

2000

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Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice

Oncogene, 1998-06, Vol.16 (24), p.3097-3104

1998

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Urokinase receptor forms in serum from non-small cell lung cancer patients: Relation to prognosis

Lung cancer (Amsterdam, Netherlands), 2011-12, Vol.74 (3), p.510-515

2011

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Metastasis is strongly reduced by the matrix metalloproteinase inhibitor Galardin in the MMTV-PymT transgenic breast cancer model

Molecular cancer therapeutics, 2008-09, Vol.7 (9), p.2758-2767

2008

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Prognosis in adenocarcinomas of lower oesophagus, gastro-oesophageal junction and cardia evaluated by uPAR-immunohistochemistry

International journal of cancer, 2012-08, Vol.131 (3), p.558-569

2012

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Metastasis of transgenic breast cancer in plasminogen activator inhibitor-1 gene-deficient mice

Oncogene, 2003-07, Vol.22 (28), p.4389-4397

2003

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Laser capture microdissection-based in vivo genomic profiling of wound keratinocytes identifies similarities and differences to squamous cell carcinoma

Oncogene, 2003-06, Vol.22 (25), p.3964-3976

2003

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Photoaffinity Labeling of the Human Receptor for Urokinase-Type Plasminogen Activator Using a Decapeptide Antagonist. Evidence for a Composite Ligand-Binding Site and a Short Interdomain Separation

Biochemistry (Easton), 1998-03, Vol.37 (11), p.3612-3622

1998

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Specific Immunoassays for Detection of Intact and Cleaved Forms of the Urokinase Receptor

Clinical chemistry (Baltimore, Md.), 2004-11, Vol.50 (11), p.2059-2068

2004

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Enhanced Discrimination of Benign from Malignant Prostatic Disease by Selective Measurements of Cleaved Forms of Urokinase Receptor in Serum

Clinical chemistry (Baltimore, Md.), 2006-05, Vol.52 (5), p.838-844

2006

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Murine monoclonal antibodies against murine uPA receptor produced in gene-deficient mice: Inhibitory effects on receptormediated uPA activity in vitro and in vivo

Thrombosis and haemostasis, 2007, Vol.97 (6), p.1013-1022

2007

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Plasminogen activation and cancer

Reduced metastasis of transgenic mammary cancer in urokinase‐deficient mice

Peptide-Derived Antagonists of the Urokinase Receptor. Affinity Maturation by Combinatorial Chemistry, Identification of Functional Epitopes, and Inhibitory Effect on Cancer Cell Intravasation

Cancer invasion and tissue remodeling: common themes in proteolytic matrix degradation

uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion

Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways

A functional overlap of plasminogen and MMPs regulates vascularization during placental development

Prognostic and predictive value of intact and cleaved forms of the urokinase plasminogen activator receptor in metastatic prostate cancer

Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor

Two distinct expression patterns of urokinase, urokinase receptor and plasminogen activator inhibitor‐1 in colon cancer liver metastases

Stromal cells associated with early invasive foci in human mammary ductal carcinoma in situ coexpress urokinase and urokinase receptor

MMP-9 Is Differentially Expressed in Primary Human Colorectal Adenocarcinomas and Their Metastases

The plasminogen fibrinolytic pathway is required for hematopoietic regeneration

Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice

Lactational competence and involution of the mouse mammary gland require plasminogen

Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice

Urokinase receptor forms in serum from non-small cell lung cancer patients: Relation to prognosis

Metastasis is strongly reduced by the matrix metalloproteinase inhibitor Galardin in the MMTV-PymT transgenic breast cancer model

Prognosis in adenocarcinomas of lower oesophagus, gastro-oesophageal junction and cardia evaluated by uPAR-immunohistochemistry

Metastasis of transgenic breast cancer in plasminogen activator inhibitor-1 gene-deficient mice

Laser capture microdissection-based in vivo genomic profiling of wound keratinocytes identifies similarities and differences to squamous cell carcinoma

Photoaffinity Labeling of the Human Receptor for Urokinase-Type Plasminogen Activator Using a Decapeptide Antagonist. Evidence for a Composite Ligand-Binding Site and a Short Interdomain Separation

Specific Immunoassays for Detection of Intact and Cleaved Forms of the Urokinase Receptor

Enhanced Discrimination of Benign from Malignant Prostatic Disease by Selective Measurements of Cleaved Forms of Urokinase Receptor in Serum

Murine monoclonal antibodies against murine uPA receptor produced in gene-deficient mice: Inhibitory effects on receptormediated uPA activity in vitro and in vivo

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