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The JAK-STAT pathway at 30: Much learned, much more to do

Cell, 2022-10, Vol.185 (21), p.3857-3876

2022

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The Innate Immune Sensor LGP2 Activates Antiviral Signaling by Regulating MDA5-RNA Interaction and Filament Assembly

Molecular cell, 2014-09, Vol.55 (5), p.771-781

2014

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RNA- and Virus-Independent Inhibition of Antiviral Signaling by RNA Helicase LGP2

Journal of Virology, 2006-12, Vol.80 (24), p.12332-12342

2006

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Regulation of Signal Transduction by Enzymatically Inactive Antiviral RNA Helicase Proteins MDA5, RIG-I, and LGP2

The Journal of biological chemistry, 2009-04, Vol.284 (15), p.9700-9712

2009

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Antiviral RNA recognition and assembly by RLR family innate immune sensors

Cytokine & growth factor reviews, 2014-10, Vol.25 (5), p.507-512

2014

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Influenza A Virus Infection of Human Respiratory Cells Induces Primary MicroRNA Expression

The Journal of biological chemistry, 2012-09, Vol.287 (37), p.31027-31040

2012

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A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory

PLoS biology, 2013-03, Vol.11 (3), p.e1001524-e1001524

2013

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Bioinformatic analysis reveals a pattern of STAT3-associated gene expression specific to basal-like breast cancers in human tumors

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (35), p.12787-12792

2014

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Small RNA profiling of influenza A virus-infected cells identifies miR-449b as a regulator of histone deacetylase 1 and interferon beta

PloS one, 2013-09, Vol.8 (9), p.e76560-e76560

2013

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A Road Map for Those Who Don't Know JAK-STAT

Science (American Association for the Advancement of Science), 2002-05, Vol.296 (5573), p.1653-1655

2002

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Dissociation of Paramyxovirus Interferon Evasion Activities: Universal and Virus-Specific Requirements for Conserved V Protein Amino Acids in MDA5 Interference

Journal of Virology, 2010-11, Vol.84 (21), p.11152-11163

2010

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Extensive Cooperation of Immune Master Regulators IRF3 and NFκB in RNA Pol II Recruitment and Pause Release in Human Innate Antiviral Transcription

Cell reports (Cambridge), 2013-09, Vol.4 (5), p.959-973

2013

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ATP Hydrolysis Enhances RNA Recognition and Antiviral Signal Transduction by the Innate Immune Sensor, Laboratory of Genetics and Physiology 2 (LGP2)

The Journal of biological chemistry, 2013-01, Vol.288 (2), p.938-946

2013

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Activation of RIG-I-like receptor signal transduction

Critical reviews in biochemistry and molecular biology, 2012-03, Vol.47 (2), p.194-206

2012

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STAT proteins and transcriptional responses to extracellular signals

Trends in Biochemical Sciences, 2000-10, Vol.25 (10), p.496-502

Horvath, Curt M

2000

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Histone H2A.Z Suppression of Interferon-Stimulated Transcription and Antiviral Immunity Is Modulated by GCN5 and BRD2

iScience, 2018-08, Vol.6, p.68-82

2018

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MicroRNA Profiling of Sendai Virus-Infected A549 Cells Identifies miR-203 as an Interferon-Inducible Regulator of IFIT1/ISG56

Journal of Virology, 2013-08, Vol.87 (16), p.9260-9270

2013

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Interferon-Stimulated Transcription and Innate Antiviral Immunity Require Deacetylase Activity and Histone Deacetylase 1

Proceedings of the National Academy of Sciences - PNAS, 2003-12, Vol.100 (25), p.14742-14747

2003

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Negative regulation of cytoplasmic RNA-mediated antiviral signaling

Cytokine (Philadelphia, Pa.), 2008-09, Vol.43 (3), p.350-358

2008

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Positive and Negative Regulation of the Innate Antiviral Response and Beta Interferon Gene Expression by Deacetylation

Molecular and Cellular Biology, 2006-04, Vol.26 (8), p.3106-3113

2006

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The TAR-RNA binding protein is required for immunoresponses triggered by Cardiovirus infection

Biochemical and biophysical research communications, 2016-11, Vol.480 (2), p.187-193

2016

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A Serpin Takes a Bite out of the Flu

Cell host & microbe, 2015-03, Vol.17 (3), p.283-284

Horvath, Curt M.

2015

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Amino Acid Requirements for MDA5 and LGP2 Recognition by Paramyxovirus V Proteins: a Single Arginine Distinguishes MDA5 from RIG-I

Journal of Virology, 2013-03, Vol.87 (5), p.2974-2978

2013

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STAT2 Is a Primary Target for Measles Virus V Protein-Mediated Alpha/Beta Interferon Signaling Inhibition

Journal of Virology, 2008-09, Vol.82 (17), p.8330-8338

2008

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Transcriptional and chromatin regulation in interferon and innate antiviral gene expression

Cytokine & growth factor reviews, 2018-12, Vol.44, p.11-17

2018

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The JAK-STAT pathway at 30: Much learned, much more to do

The Innate Immune Sensor LGP2 Activates Antiviral Signaling by Regulating MDA5-RNA Interaction and Filament Assembly

RNA- and Virus-Independent Inhibition of Antiviral Signaling by RNA Helicase LGP2

Regulation of Signal Transduction by Enzymatically Inactive Antiviral RNA Helicase Proteins MDA5, RIG-I, and LGP2

Antiviral RNA recognition and assembly by RLR family innate immune sensors

Influenza A Virus Infection of Human Respiratory Cells Induces Primary MicroRNA Expression

A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory

Bioinformatic analysis reveals a pattern of STAT3-associated gene expression specific to basal-like breast cancers in human tumors

Small RNA profiling of influenza A virus-infected cells identifies miR-449b as a regulator of histone deacetylase 1 and interferon beta

A Road Map for Those Who Don't Know JAK-STAT

Dissociation of Paramyxovirus Interferon Evasion Activities: Universal and Virus-Specific Requirements for Conserved V Protein Amino Acids in MDA5 Interference

Extensive Cooperation of Immune Master Regulators IRF3 and NFκB in RNA Pol II Recruitment and Pause Release in Human Innate Antiviral Transcription

ATP Hydrolysis Enhances RNA Recognition and Antiviral Signal Transduction by the Innate Immune Sensor, Laboratory of Genetics and Physiology 2 (LGP2)

Activation of RIG-I-like receptor signal transduction

STAT proteins and transcriptional responses to extracellular signals

Histone H2A.Z Suppression of Interferon-Stimulated Transcription and Antiviral Immunity Is Modulated by GCN5 and BRD2

MicroRNA Profiling of Sendai Virus-Infected A549 Cells Identifies miR-203 as an Interferon-Inducible Regulator of IFIT1/ISG56

Interferon-Stimulated Transcription and Innate Antiviral Immunity Require Deacetylase Activity and Histone Deacetylase 1

Negative regulation of cytoplasmic RNA-mediated antiviral signaling

Positive and Negative Regulation of the Innate Antiviral Response and Beta Interferon Gene Expression by Deacetylation

The TAR-RNA binding protein is required for immunoresponses triggered by Cardiovirus infection

A Serpin Takes a Bite out of the Flu

Amino Acid Requirements for MDA5 and LGP2 Recognition by Paramyxovirus V Proteins: a Single Arginine Distinguishes MDA5 from RIG-I

STAT2 Is a Primary Target for Measles Virus V Protein-Mediated Alpha/Beta Interferon Signaling Inhibition

Transcriptional and chromatin regulation in interferon and innate antiviral gene expression

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