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Design, Synthesis, and Biological Evaluation of Erythrina Alkaloid Analogues as Neuronal Nicotinic Acetylcholine Receptor Antagonists

Journal of medicinal chemistry, 2013-12, Vol.56 (23), p.9673-9682

2013

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Expedite Protocol for Construction of Chiral Regioselectively N-Protected Monosubstituted Piperazine, 1,4-Diazepane, and 1,4-Diazocane Building Blocks

Journal of organic chemistry, 2009-08, Vol.74 (15), p.5652-5655

2009

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Chemo- and Regioselective Functionalization of Nortrilobolide: Application for Semisynthesis of the Natural Product 2‑Acetoxytrilobolide

Journal of natural products (Washington, D.C.), 2015-06, Vol.78 (6), p.1406-1414

2015

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Total synthesis of ascididemin via anionic cascade ring closure

Chemical communications (Cambridge, England), 2012-09, Vol.48 (72), p.9092-9094

2012

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Concise synthesis of thapsigargin from nortrilobolide

Tetrahedron letters, 2015-10, Vol.56 (43), p.5896-5898

2015

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A strategic approach to [6,6]-bicyclic lactones: application towards the CD fragment of DHβE

Beilstein journal of organic chemistry, 2017-05, Vol.13 (1), p.988-994

2017

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Trifunctionalization of the Purine Scaffold Using Mg and Zn Organometallic Intermediates

Organic letters, 2011-02, Vol.13 (4), p.792-795

2011

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Dual Nicotinic Acetylcholine Receptor α4β2 Antagonists/α7 Agonists: Synthesis, Docking Studies, and Pharmacological Evaluation of Tetrahydroisoquinolines and Tetrahydroisoquinolinium Salts

Journal of medicinal chemistry, 2018-02, Vol.61 (4), p.1719-1729

2018

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Concise synthesis of new bridged-nicotine analogues

Tetrahedron, 2012-02, Vol.68 (5), p.1417-1421

2012

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Tying up Nicotine: New Selective Competitive Antagonist of the Neuronal Nicotinic Acetylcholine Receptors

ACS medicinal chemistry letters, 2015-04, Vol.6 (4), p.472-475

2015

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Microwave-Assisted Ring-Opening of Activated Aziridines with Resin-Bound Amines

Journal of organic chemistry, 2008-05, Vol.73 (9), p.3566-3569

2008

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Radiosynthesis and preclinical evaluation of [11C]Cimbi‐701 – Towards the imaging of cerebral 5‐HT7 receptors

Journal of labelled compounds & radiopharmaceuticals, 2020-02, Vol.63 (2), p.46-55

2020

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Efficient loading of primary alcohols onto a solid phase using a trityl bromide linker

Tetrahedron letters, 2008-10, Vol.49 (41), p.5890-5893

2008

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A new and efficient synthesis of 2-azatryptophans

Tetrahedron, 2006-08, Vol.62 (33), p.7772-7775

2006

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Design and synthesis of a new indazole library: direct conversion of N-methoxy- N-methylamides (Weinreb amides) to 3-keto and 3-formylindazoles

Tetrahedron, 2007-01, Vol.63 (2), p.419-428

2007

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Identification and Electrophysiological Evaluation of 2‑Methylbenzamide Derivatives as Nav1.1 Modulators

ACS chemical neuroscience, 2015-08, Vol.6 (8), p.1302-1308

2015

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Synthesis of New Dehydro 2-Azatryptophans and Derivatives via Heck Cross-Coupling Reactions of 3-Iodoindazoles with Methyl 2-(Acetylamino)acrylate

Synthesis (Stuttgart), 2006-10, Vol.2006 (20), p.3506-3514

2006

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A Simple and Efficient Synthesis of New Mono- and Bis([1,2,4]-oxadiazol)-benzaldehyde Building Blocks

Synthesis (Stuttgart), 2007-11, Vol.2007 (21), p.3406-3410

2007

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New practical access to 2-azatryptophans and dehydro derivatives via the Wittig–Horner reaction

Tetrahedron letters, 2007-04, Vol.48 (14), p.2457-2460

2007

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A small molecule activator of Nav1.1 channels increases fast‐spiking interneuron excitability and GABAergic transmission in vitro and has anti‐convulsive effects in vivo

The European journal of neuroscience, 2017-08, Vol.46 (3), p.1887-1896

2017

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Direct Cu-mediated aromatic 18 F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging

Chemical science (Cambridge), 2021-09, Vol.12 (35), p.11668-11675

2021

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Direct Cu-mediated aromatic 18F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging

Chemical science (Cambridge), 2021-09, Vol.12 (35), p.11668-11675

2021

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Total synthesis of ascididemin via anionic cascade ring closureElectronic supplementary information (ESI) available: Detailed experimental procedures and copies of NMR-spectra for all compounds. See DOI: 10.1039/c2cc34725c

2012-08

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A small molecule activator of Na v 1.1 channels increases fast-spiking interneuron excitability and GABAergic transmission in vitro and has anti-convulsive effects in vivo

The European journal of neuroscience, 2017-08, Vol.46 (3), p.1887-1896

2017

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A small molecule activator of Nav1.1 channels increases fast-spiking interneuron excitability and GABAergic transmission inￂ vitro and has anti-convulsive effects inￂ vivo

The European journal of neuroscience, 2017-08, Vol.46 (3), p.1887

2017

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Design, Synthesis, and Biological Evaluation of Erythrina Alkaloid Analogues as Neuronal Nicotinic Acetylcholine Receptor Antagonists

Expedite Protocol for Construction of Chiral Regioselectively N-Protected Monosubstituted Piperazine, 1,4-Diazepane, and 1,4-Diazocane Building Blocks

Chemo- and Regioselective Functionalization of Nortrilobolide: Application for Semisynthesis of the Natural Product 2‑Acetoxytrilobolide

Total synthesis of ascididemin via anionic cascade ring closure

Concise synthesis of thapsigargin from nortrilobolide

A strategic approach to [6,6]-bicyclic lactones: application towards the CD fragment of DHβE

Trifunctionalization of the Purine Scaffold Using Mg and Zn Organometallic Intermediates

Dual Nicotinic Acetylcholine Receptor α4β2 Antagonists/α7 Agonists: Synthesis, Docking Studies, and Pharmacological Evaluation of Tetrahydroisoquinolines and Tetrahydroisoquinolinium Salts

Concise synthesis of new bridged-nicotine analogues

Tying up Nicotine: New Selective Competitive Antagonist of the Neuronal Nicotinic Acetylcholine Receptors

Microwave-Assisted Ring-Opening of Activated Aziridines with Resin-Bound Amines

Radiosynthesis and preclinical evaluation of [11C]Cimbi‐701 – Towards the imaging of cerebral 5‐HT7 receptors

Efficient loading of primary alcohols onto a solid phase using a trityl bromide linker

A new and efficient synthesis of 2-azatryptophans

Design and synthesis of a new indazole library: direct conversion of N-methoxy- N-methylamides (Weinreb amides) to 3-keto and 3-formylindazoles

Identification and Electrophysiological Evaluation of 2‑Methylbenzamide Derivatives as Nav1.1 Modulators

Synthesis of New Dehydro 2-Azatryptophans and Derivatives via Heck Cross-Coupling Reactions of 3-Iodoindazoles with Methyl 2-(Acetylamino)acrylate

A Simple and Efficient Synthesis of New Mono- and Bis([1,2,4]-oxadiazol)-benzaldehyde Building Blocks

New practical access to 2-azatryptophans and dehydro derivatives via the Wittig–Horner reaction

A small molecule activator of Nav1.1 channels increases fast‐spiking interneuron excitability and GABAergic transmission in vitro and has anti‐convulsive effects in vivo

Direct Cu-mediated aromatic 18 F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging

Direct Cu-mediated aromatic 18F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging

Total synthesis of ascididemin via anionic cascade ring closureElectronic supplementary information (ESI) available: Detailed experimental procedures and copies of NMR-spectra for all compounds. See DOI: 10.1039/c2cc34725c

A small molecule activator of Na v 1.1 channels increases fast-spiking interneuron excitability and GABAergic transmission in vitro and has anti-convulsive effects in vivo

A small molecule activator of Nav1.1 channels increases fast-spiking interneuron excitability and GABAergic transmission inￂ vitro and has anti-convulsive effects inￂ vivo

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