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A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

Nature medicine, 2015-01, Vol.21 (1), p.27-36

2015

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Incretin-like effects of small molecule trace amine-associated receptor 1 agonists

Molecular metabolism (Germany), 2016-01, Vol.5 (1), p.47-56

2016

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Autotaxin Inhibitor Protects from Chronic Allograft Injury in Rat Kidney Allotransplantation

Nephron (2015), 2020-01, Vol.144 (1), p.38-48

2020

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Heparan sulfate proteoglycans in experimental models of diabetes: a role for perlecan in diabetes complications

Diabetes/metabolism research and reviews, 2001-11, Vol.17 (6), p.412-421

Conde-Knape, Karin

2001

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Delayed catabolism of apoB-48 lipoproteins due to decreased heparan sulfate proteoglycan production in diabetic mice

The Journal of clinical investigation, 2000-06, Vol.105 (12), p.1807-1818

2000

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Fatty acids increase presenilin-1 levels and γ-secretase activity in PSwt-1 cells

Journal of lipid research, 2004-12, Vol.45 (12), p.2368-2376

2004

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Hypolipidemic mechanisms of pectin and psyllium in guinea pigs fed high fat-sucrose diets: alterations on hepatic cholesterol metabolism

Journal of lipid research, 1998-07, Vol.39 (7), p.1455-1465

1998

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Overexpression ofapoC-III produces lesser hypertriglyceridemia in apoB-48-only gene-targeted micethan in apoB-100-only mice

Journal of lipid research, 2004-12, Vol.45 (12), p.2235-2244

2004

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Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture

Journal of the American College of Cardiology, 2023-06, Vol.81 (23), p.2213-2227

2023

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BMP7-induced-Pten inhibits Akt and prevents renal fibrosis

Biochimica et biophysica acta. Molecular basis of disease, 2017-12, Vol.1863 (12), p.3095-3104

2017

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Men Classified as Hypo- or Hyperresponders to Dietary Cholesterol Feeding Exhibit Differences in Lipoprotein Metabolism

The Journal of nutrition, 2003-04, Vol.133 (4), p.1036-1042

2003

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Overexpression of apoC-I in apoE-null mice

Journal of lipid research, 2002-12, Vol.43 (12), p.2136-2145

2002

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Preparation and Characterization of Albumin Conjugates of a Truncated Peptide YY Analogue for Half-Life Extension

Bioconjugate chemistry, 2013-12, Vol.24 (12), p.2015-2024

2013

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Design and synthesis of 2-N-substituted indazolone derivatives as non-carboxylic acid glycogen synthase activators

Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (10), p.2936-2940

2013

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PK modulation of haptenylated peptides via non-covalent antibody complexation

Journal of controlled release, 2013-10, Vol.171 (1), p.48-56

2013

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Discovery of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists

Bioorganic & medicinal chemistry letters, 2014-02, Vol.24 (3), p.949-953

2014

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Potent MCH-1 receptor antagonists from cis-1,4-diaminocyclohexane-derived indane analogs

Bioorganic & medicinal chemistry letters, 2013-07, Vol.23 (14), p.4216-4220

2013

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Discovery of 1-arylcarbonyl-6,7-dimethoxyisoquinoline derivatives as glutamine fructose-6-phosphate amidotransferase (GFAT) inhibitors

Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (21), p.6264-6269

2011

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Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonists

Bioorganic & medicinal chemistry letters, 2013-08, Vol.23 (16), p.4627-4632

2013

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Discovery and optimization of 2-phenyloxazole derivatives as diacylglycerol acyltransferase-1 inhibitors

Bioorganic & medicinal chemistry letters, 2011-12, Vol.21 (23), p.7205-7209

2011

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Hamsters and Guinea pigs differ in their plasma lipoprotein cholesterol distribution when fed diets varying in animal protein, soluble fiber, or cholesterol content

The Journal of nutrition, 1999-07, Vol.129 (7), p.1323-1332

1999

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A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

Incretin-like effects of small molecule trace amine-associated receptor 1 agonists

Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans

Autotaxin Inhibitor Protects from Chronic Allograft Injury in Rat Kidney Allotransplantation

Heparan sulfate proteoglycans in experimental models of diabetes: a role for perlecan in diabetes complications

Delayed catabolism of apoB-48 lipoproteins due to decreased heparan sulfate proteoglycan production in diabetic mice

Fatty acids increase presenilin-1 levels and γ-secretase activity in PSwt-1 cells

Hypolipidemic mechanisms of pectin and psyllium in guinea pigs fed high fat-sucrose diets: alterations on hepatic cholesterol metabolism

Overexpression ofapoC-III produces lesser hypertriglyceridemia in apoB-48-only gene-targeted micethan in apoB-100-only mice

Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture

BMP7-induced-Pten inhibits Akt and prevents renal fibrosis

Discovery of 2‑[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia

A neutralizing antibody against DKK1 does not reduce plaque formation in classical murine models of atherosclerosis: Is the therapeutic potential lost in translation?

Men Classified as Hypo- or Hyperresponders to Dietary Cholesterol Feeding Exhibit Differences in Lipoprotein Metabolism

Overexpression of apoC-I in apoE-null mice

Preparation and Characterization of Albumin Conjugates of a Truncated Peptide YY Analogue for Half-Life Extension

Design and synthesis of 2-N-substituted indazolone derivatives as non-carboxylic acid glycogen synthase activators

PK modulation of haptenylated peptides via non-covalent antibody complexation

Discovery of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists

Discovery of Orally Active Carboxylic Acid Derivatives of 2-Phenyl-5-trifluoromethyloxazole-4-carboxamide as Potent Diacylglycerol Acyltransferase-1 Inhibitors for the Potential Treatment of Obesity and Diabetes

Potent MCH-1 receptor antagonists from cis-1,4-diaminocyclohexane-derived indane analogs

Discovery of 1-arylcarbonyl-6,7-dimethoxyisoquinoline derivatives as glutamine fructose-6-phosphate amidotransferase (GFAT) inhibitors

Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonists

Discovery and optimization of 2-phenyloxazole derivatives as diacylglycerol acyltransferase-1 inhibitors

Hamsters and Guinea pigs differ in their plasma lipoprotein cholesterol distribution when fed diets varying in animal protein, soluble fiber, or cholesterol content

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