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Fibroblast Growth Factor 2 and Its Receptors in Bone Biology and Disease

Journal of the Endocrine Society, 2018-07, Vol.2 (7), p.657-671

2018

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FGF receptor inhibitor BGJ398 partially rescues osteoarthritis-like phenotype in older high molecular weight FGF2 transgenic mice via multiple mechanisms

Scientific reports, 2022-09, Vol.12 (1), p.15968-15968, Article 15968

2022

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Fibroblast Growth Factor 2 Stimulation of Osteoblast Differentiation and Bone Formation Is Mediated by Modulation of the Wnt Signaling Pathway

The Journal of biological chemistry, 2011-11, Vol.286 (47), p.40575-40583

2011

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FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation

Blood, 2012-08, Vol.120 (9), p.1843-1855

2012

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Disruption of the Fgf2 gene activates the adipogenic and suppresses the osteogenic program in mesenchymal marrow stromal stem cells

Bone (New York, N.Y.), 2010-08, Vol.47 (2), p.360-370

2010

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BMP-2 Differentially Modulates FGF-2 Isoform Effects in Osteoblasts From Newborn Transgenic Mice

Endocrinology (Philadelphia), 2013-08, Vol.154 (8), p.2723-2733

2013

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Nuclear Isoforms of Fibroblast Growth Factor 2 Are Novel Inducers of Hypophosphatemia via Modulation of FGF23 and KLOTHO

The Journal of biological chemistry, 2010-01, Vol.285 (4), p.2834-2846

2010

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Exported 18-kDa Isoform of Fibroblast Growth Factor-2 Is a Critical Determinant of Bone Mass in Mice

The Journal of biological chemistry, 2009-01, Vol.284 (5), p.3170-3182

2009

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Endogenous FGF-2 is critically important in PTH anabolic effects on bone

Journal of cellular physiology, 2009-04, Vol.219 (1), p.143-151

2009

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Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3

Development (Cambridge), 1998-12, Vol.125 (24), p.4977-4988

1998

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Stat1 Controls Postnatal Bone Formation by Regulating Fibroblast Growth Factor Signaling in Osteoblasts

The Journal of biological chemistry, 2004-06, Vol.279 (26), p.27743-27752

2004

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Activation of protein kinase C and disruption of endothelial monolayer integrity by sodium arsenite—Potential mechanism in the development of atherosclerosis

Toxicology and applied pharmacology, 2007-04, Vol.220 (2), p.164-177

2007

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Impaired Osteoclast Formation in Bone Marrow Cultures of Fgf2 Null Mice in Response to Parathyroid Hormone

The Journal of biological chemistry, 2003-06, Vol.278 (23), p.21258-21266

2003

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Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation

The Journal of clinical investigation, 2000-04, Vol.105 (8), p.1085-1093

2000

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Arsenic Exposure in Pregnant Mice Disrupts Placental Vasculogenesis and Causes Spontaneous Abortion

Toxicological sciences, 2007-09, Vol.99 (1), p.244-253

2007

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The influence of FGF2 high molecular weight (HMW) isoforms in the development of cardiac ischemia–reperfusion injury

Journal of molecular and cellular cardiology, 2010-06, Vol.48 (6), p.1245-1254

2010

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FGF-2 Overexpression Increases Excitability and Seizure Susceptibility but Decreases Seizure-Induced Cell Loss

The Journal of neuroscience, 2008-12, Vol.28 (49), p.13112-13124

2008

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Arsenic exposure exacerbates atherosclerotic plaque formation and increases nitrotyrosine and leukotriene biosynthesis

Toxicology and applied pharmacology, 2004-11, Vol.201 (1), p.32-39

2004

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Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis

Nature neuroscience, 1999-03, Vol.2 (3), p.246-253

1999

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STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation in mice overexpressing FGF2

Development (Cambridge), 2001-06, Vol.128 (11), p.2119-2129

2001

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Arsenic Induces Peroxynitrite Generation and Cyclooxygenase-2 Protein Expression in Aortic Endothelial Cells: Possible Role in Atherosclerosis

Toxicology and applied pharmacology, 2002-10, Vol.184 (1), p.11-18

2002

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Fibroblast growth factor 2 control of vascular tone

Nature medicine, 1998-02, Vol.4 (2), p.201-207

1998

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Focal cerebral ischemia upregulates SHP-1 in reactive astrocytes in juvenile mice

Brain research, 2003-06, Vol.974 (1), p.88-98

2003

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Lack of the protein tyrosine phosphatase SHP-1 results in decreased numbers of glia within the motheaten (me/me) mouse brain

Journal of comparative neurology (1911), 2001-12, Vol.441 (2), p.118-133

2001

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Immunohistologic labeling of murine endothelium

Cardiovascular pathology, 2003-03, Vol.12 (2), p.82-90

2003

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Fibroblast Growth Factor 2 and Its Receptors in Bone Biology and Disease

FGF receptor inhibitor BGJ398 partially rescues osteoarthritis-like phenotype in older high molecular weight FGF2 transgenic mice via multiple mechanisms

Fibroblast Growth Factor 2 Stimulation of Osteoblast Differentiation and Bone Formation Is Mediated by Modulation of the Wnt Signaling Pathway

FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation

Disruption of the Fgf2 gene activates the adipogenic and suppresses the osteogenic program in mesenchymal marrow stromal stem cells

BMP-2 Differentially Modulates FGF-2 Isoform Effects in Osteoblasts From Newborn Transgenic Mice

Nuclear Isoforms of Fibroblast Growth Factor 2 Are Novel Inducers of Hypophosphatemia via Modulation of FGF23 and KLOTHO

Exported 18-kDa Isoform of Fibroblast Growth Factor-2 Is a Critical Determinant of Bone Mass in Mice

Endogenous FGF-2 is critically important in PTH anabolic effects on bone

Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3

Stat1 Controls Postnatal Bone Formation by Regulating Fibroblast Growth Factor Signaling in Osteoblasts

Activation of protein kinase C and disruption of endothelial monolayer integrity by sodium arsenite—Potential mechanism in the development of atherosclerosis

Impaired Osteoclast Formation in Bone Marrow Cultures of Fgf2 Null Mice in Response to Parathyroid Hormone

Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation

Arsenic Exposure in Pregnant Mice Disrupts Placental Vasculogenesis and Causes Spontaneous Abortion

The influence of FGF2 high molecular weight (HMW) isoforms in the development of cardiac ischemia–reperfusion injury

FGF-2 Overexpression Increases Excitability and Seizure Susceptibility but Decreases Seizure-Induced Cell Loss

Arsenic exposure exacerbates atherosclerotic plaque formation and increases nitrotyrosine and leukotriene biosynthesis

Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis

STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation in mice overexpressing FGF2

Arsenic Induces Peroxynitrite Generation and Cyclooxygenase-2 Protein Expression in Aortic Endothelial Cells: Possible Role in Atherosclerosis

Fibroblast growth factor 2 control of vascular tone

Focal cerebral ischemia upregulates SHP-1 in reactive astrocytes in juvenile mice

Lack of the protein tyrosine phosphatase SHP-1 results in decreased numbers of glia within the motheaten (me/me) mouse brain

Immunohistologic labeling of murine endothelium

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