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FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

The New England journal of medicine, 2015-09, Vol.373 (10), p.895-907

2015

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High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human

Nature communications, 2018-12, Vol.9 (1), p.5380-15, Article 5380

2018

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Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots

Nature communications, 2022-06, Vol.13 (1), p.3771-3771, Article 3771

2022

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A distribution-centered approach for analyzing human adipocyte size estimates and their association with obesity-related traits and mitochondrial function

International Journal of Obesity, 2021-09, Vol.45 (9), p.2108-2117

2021

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BMI-adjusted adipose tissue volumes exhibit depot-specific and divergent associations with cardiometabolic diseases

Nature communications, 2023-01, Vol.14 (1), p.266-266, Article 266

2023

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miR-375 is cold exposure sensitive and drives thermogenesis in visceral adipose tissue derived stem cells

Scientific reports, 2022-06, Vol.12 (1), p.9557-9557, Article 9557

2022

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Minimum information and guidelines for reporting a multiplexed assay of variant effect

Genome Biology, 2024-04, Vol.25 (1), p.100-8, Article 100

2024

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Gaining insight into metabolic diseases from human genetic discoveries

Trends in genetics, 2021-12, Vol.37 (12), p.1081-1094

2021

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Identification of a weight loss-associated causal eQTL in MTIF3 and the effects of MTIF3 deficiency on human adipocyte function

eLife, 2023-03, Vol.12

2023

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Specific miRNAs are associated with human cancer cachexia in an organ‐specific manner

Journal of cachexia, sarcopenia and muscle, 2023-06, Vol.14 (3), p.1381-1394

2023

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Transcriptome and fatty-acid signatures of adipocyte hypertrophy and its non-invasive MR-based characterization in human adipose tissue

EBioMedicine, 2022-05, Vol.79, p.104020-104020, Article 104020

2022

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Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits

PLoS computational biology, 2020-08, Vol.16 (8), p.e1008044-e1008044

2020

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Effect of BMI on the Thermogenic Response to Cold Exposure and Associated Changes in Metabolism and Browning Markers in Adult Humans

Obesity facts, 2022, Vol.15 (3), p.405-415

2022

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Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146

PloS one, 2013-10, Vol.8 (10), p.e78430-e78430

2013

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Functional Characterization of Promoter Variants of the Adiponectin Gene Complemented by Epidemiological Data

Diabetes (New York, N.Y.), 2009-04, Vol.58 (4), p.984-991

2009

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Scalable Functional Assays for the Interpretation of Human Genetic Variation

Annual review of genetics, 2022-11, Vol.56, p.441

2022

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A brief history of human disease genetics

Nature (London), 2020-01, Vol.577 (7789), p.179-189

2020

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Landscape of X chromosome inactivation across human tissues

Nature (London), 2017-10, Vol.550 (7675), p.244-248

2017

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Integrative analysis of 111 reference human epigenomes

Nature (London), 2015-02, Vol.518 (7539), p.317-330

2015

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Gender Differences in the Response to Short-term Cold Exposure in Young Adults

The journal of clinical endocrinology and metabolism, 2020-05, Vol.105 (5), p.e1938-e1948

2020

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Dynamic landscape and regulation of RNA editing in mammals

Nature (London), 2017-10, Vol.550 (7675), p.249-254

2017

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Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

Nature (London), 2015-10, Vol.526 (7571), p.112-117

2015

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Feature Selection Pipelines with Classification for Non-targeted Metabolomics Combining the Neural Network and Genetic Algorithm

Analytical chemistry (Washington), 2022-04, Vol.94 (14), p.5474-5482

2022

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Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5

Science (American Association for the Advancement of Science), 2021-06, Vol.372 (6546), p.1085-1091

2021

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Engineered allele substitution at PPARGC1A rs8192678 alters human white adipocyte differentiation, lipogenesis, and PGC-1α content and turnover

Diabetologia, 2023-07, Vol.66 (7), p.1289-1305

2023

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FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human

Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots

A distribution-centered approach for analyzing human adipocyte size estimates and their association with obesity-related traits and mitochondrial function

BMI-adjusted adipose tissue volumes exhibit depot-specific and divergent associations with cardiometabolic diseases

miR-375 is cold exposure sensitive and drives thermogenesis in visceral adipose tissue derived stem cells

Minimum information and guidelines for reporting a multiplexed assay of variant effect

Gaining insight into metabolic diseases from human genetic discoveries

Identification of a weight loss-associated causal eQTL in MTIF3 and the effects of MTIF3 deficiency on human adipocyte function

Specific miRNAs are associated with human cancer cachexia in an organ‐specific manner

Transcriptome and fatty-acid signatures of adipocyte hypertrophy and its non-invasive MR-based characterization in human adipose tissue

Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits

Effect of BMI on the Thermogenic Response to Cold Exposure and Associated Changes in Metabolism and Browning Markers in Adult Humans

Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146

Functional Characterization of Promoter Variants of the Adiponectin Gene Complemented by Epidemiological Data

Scalable Functional Assays for the Interpretation of Human Genetic Variation

A brief history of human disease genetics

Landscape of X chromosome inactivation across human tissues

Integrative analysis of 111 reference human epigenomes

Gender Differences in the Response to Short-term Cold Exposure in Young Adults

Dynamic landscape and regulation of RNA editing in mammals

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

Feature Selection Pipelines with Classification for Non-targeted Metabolomics Combining the Neural Network and Genetic Algorithm

Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5

Engineered allele substitution at PPARGC1A rs8192678 alters human white adipocyte differentiation, lipogenesis, and PGC-1α content and turnover

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