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Effects of an Inhibitor of Cholesteryl Ester Transfer Protein on HDL Cholesterol

The New England journal of medicine, 2004-04, Vol.350 (15), p.1505-1515

2004

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The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats

PloS one, 2014-05, Vol.9 (5), p.e97139

2014

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Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)

Journal of medicinal chemistry, 2015-09, Vol.58 (18), p.7173-7185

2015

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Mice deleted for GPAT3 have reduced GPAT activity in white adipose tissue and altered energy and cholesterol homeostasis in diet-induced obesity

American journal of physiology: endocrinology and metabolism, 2014-05, Vol.306 (10), p.E1176-E1187

2014

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Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules

Nature structural & molecular biology, 2007-02, Vol.14 (2), p.106-113

2007

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Description of the torcetrapib series of cholesteryl ester transfer protein inhibitors, including mechanism of action

Journal of lipid research, 2006-03, Vol.47 (3), p.537-552

2006

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Assessment of cholesteryl ester transfer protein inhibitors for interaction with proteins involved in the immune response to infection[S]

Journal of lipid research, 2010-05, Vol.51 (5), p.967-974

2010

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Characterization of a Novel Intestinal Glycerol-3-phosphate Acyltransferase Pathway and Its Role in Lipid Homeostasis

The Journal of biological chemistry, 2016-02, Vol.291 (6), p.2602-2615

2016

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Crystal Structures of Cholesteryl Ester Transfer Protein in Complex with Inhibitors

The Journal of biological chemistry, 2012-10, Vol.287 (44), p.37321-37329

2012

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Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: an initial multidose study of torcetrapib

Arteriosclerosis, thrombosis, and vascular biology, 2004-03, Vol.24 (3), p.490-497

2004

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Raising high-density lipoprotein with cholesteryl ester transfer protein inhibitors

Current opinion in pharmacology, 2006-04, Vol.6 (2), p.162-168

Clark, Ronald W

2006

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Identification of a novel, non-tetrahydroquinoline variant of the cholesteryl ester transfer protein (CETP) inhibitor torcetrapib, with improved aqueous solubility

Xenobiotica, 2014-07, Vol.44 (7), p.591-605

2014

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Polymorphisms in the CETP gene and association with CETP mass and HDL levels

Atherosclerosis, 2003-04, Vol.167 (2), p.195-204

2003

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Inhibition of cholesteryl ester transfer protein activity in hamsters alters HDL lipid composition

Atherosclerosis, 1994-09, Vol.110 (1), p.101-109

1994

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Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

The Journal of biological chemistry, 1993-05, Vol.268 (15), p.11230-11238

1993

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Description of the torcetrapib series of cholesteryl ester transfer protein inhibitors, including mechanism of actions

Journal of lipid research, 2006-03, Vol.47 (3), p.537-552

2006

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Cholesteryl ester transfer protein inhibition and the treatment of metabolic syndrome

Drug discovery today. Therapeutic strategies, 2005, Vol.2 (2), p.117-124

2005

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Carbamate formation on tubulin: carbon dioxide/bicarbonate buffers protect tubulin from inactivation by reductive methylation and carbamoylation and promote microtubule assembly at alkaline pH

Biochemistry (Easton), 1988-02, Vol.27 (3), p.1025-1033

1988

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Bertrand Russell

Nature (London), 1972-04, Vol.236 (5347), p.413-413

CLARK, RONALD W

1972

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The Junior High School in Illinois outside Chicago

School Review, 1933-05, Vol.41 (5), p.337-346

Clark, Ronald W.

1933

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Promoting Spontaneous Use of Learning and Reasoning Strategies: Theory, research, and practice for effective transfer

1st edition., 2018

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Personality adjustments of ninth-grade pupils as measured by the Multiple Choice Rorschach Test and the California Test of Personality

Journal of educational psychology, 1946-01, Vol.37 (1), p.13-20

1946

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Agents for the Inhibition of Cholesteryl Ester Transfer Protein (CETP) and Prospects for the Future Treatment of Atherosclerosis

Current medicinal chemistry. Immunology, endocrine & metabolic agents, 2005-08, Vol.5 (4), p.339-360

2005

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Carbamate formation on tubulin: CO2/bicarbonate buffers protect tubulin from inactivation by reductive methylation and carbamoylation and promote microtubule assembly at alkaline pH

Biochemistry (Easton), 1988-02, Vol.27 (3), p.1025-1033

1988

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Effects of an Inhibitor of Cholesteryl Ester Transfer Protein on HDL Cholesterol

The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats

Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)

Mice deleted for GPAT3 have reduced GPAT activity in white adipose tissue and altered energy and cholesterol homeostasis in diet-induced obesity

Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules

Description of the torcetrapib series of cholesteryl ester transfer protein inhibitors, including mechanism of action

Assessment of cholesteryl ester transfer protein inhibitors for interaction with proteins involved in the immune response to infection[S]

Discovery of Ervogastat (PF-06865571): A Potent and Selective Inhibitor of Diacylglycerol Acyltransferase 2 for the Treatment of Non-alcoholic Steatohepatitis

Characterization of a Novel Intestinal Glycerol-3-phosphate Acyltransferase Pathway and Its Role in Lipid Homeostasis

Crystal Structures of Cholesteryl Ester Transfer Protein in Complex with Inhibitors

Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: an initial multidose study of torcetrapib

Raising high-density lipoprotein with cholesteryl ester transfer protein inhibitors

Identification of a novel, non-tetrahydroquinoline variant of the cholesteryl ester transfer protein (CETP) inhibitor torcetrapib, with improved aqueous solubility

Polymorphisms in the CETP gene and association with CETP mass and HDL levels

Inhibition of cholesteryl ester transfer protein activity in hamsters alters HDL lipid composition

Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

Description of the torcetrapib series of cholesteryl ester transfer protein inhibitors, including mechanism of actions

Cholesteryl ester transfer protein inhibition and the treatment of metabolic syndrome

Carbamate formation on tubulin: carbon dioxide/bicarbonate buffers protect tubulin from inactivation by reductive methylation and carbamoylation and promote microtubule assembly at alkaline pH

Bertrand Russell

The Junior High School in Illinois outside Chicago

Promoting Spontaneous Use of Learning and Reasoning Strategies: Theory, research, and practice for effective transfer

Personality adjustments of ninth-grade pupils as measured by the Multiple Choice Rorschach Test and the California Test of Personality

Agents for the Inhibition of Cholesteryl Ester Transfer Protein (CETP) and Prospects for the Future Treatment of Atherosclerosis

Carbamate formation on tubulin: CO2/bicarbonate buffers protect tubulin from inactivation by reductive methylation and carbamoylation and promote microtubule assembly at alkaline pH

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