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Binding pathway determines norepinephrine selectivity for the human β1AR over β2AR

Cell research, 2021-05, Vol.31 (5), p.569-579

2021

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Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (47), p.12046-12050

2018

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Discovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptor

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (26), p.10830-10835

2013

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Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics

Nature communications, 2023-04, Vol.14 (1), p.2138-2138, Article 2138

2023

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Author Correction: Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics

Nature communications, 2023-05, Vol.14 (1), p.2992-2992, Article 2992

2023

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Structure-Based Design and Discovery of New M2 Receptor Agonists

Journal of medicinal chemistry, 2017-11, Vol.60 (22), p.9239-9250

2017

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Nucleus accumbens shell excitability is decreased by methamphetamine self-administration and increased by 5-HT2C receptor inverse agonism and agonism

Neuropharmacology, 2015-02, Vol.89, p.113-121

2015

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Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane

Nature (London), 2020-08, Vol.584 (7819), p.125-129

2020

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Structure and selectivity engineering of the M 1 muscarinic receptor toxin complex

Science (American Association for the Advancement of Science), 2020-07, Vol.369 (6500), p.161-167

2020

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Leveraging nonstructural data to predict structures and affinities of protein-ligand complexes

Proceedings of the National Academy of Sciences - PNAS, 2021-12, Vol.118 (51)

2021

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Structure-based discovery of selective positive allosteric modulators of antagonists for the M₂ muscarinic acetylcholine receptor

Proceedings of the National Academy of Sciences - PNAS, 2018-03, Vol.115 (10), p.E2419-E2428

2018

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The Relationship Between the Medical Home and Unmet Needs for Children with Autism Spectrum Disorders

Maternal and child health journal, 2014-04, Vol.18 (3), p.672-680

2014

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Structure and selectivity engineering of the M1 muscarinic receptor toxin complex

Science (American Association for the Advancement of Science), 2020-07, Vol.369 (6500), p.161-167

2020

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Developmental Monitoring and Referral for Low-Income Children Served by WIC: Program Development and Implementation Outcomes

Maternal and child health journal, 2022-02, Vol.26 (2), p.230-241

2022

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C7β-Methyl Analogues of the Orvinols: The Discovery of Kappa Opioid Antagonists with Nociceptin/Orphanin FQ Peptide (NOP) Receptor Partial Agonism and Low, or Zero, Efficacy at Mu Opioid Receptors

Journal of medicinal chemistry, 2015-05, Vol.58 (10), p.4242-4249

2015

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Consultative Care Coordination Through the Medical Home for CSHCN: A Randomized Controlled Trial

Maternal and child health journal, 2011-10, Vol.15 (7), p.1110-1118

2011

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Act Healthy: promoting health behaviors and self-efficacy in the workplace

Health education research, 2015-08, Vol.30 (4), p.542-553

2015

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Orvinols with Mixed Kappa/Mu Opioid Receptor Agonist Activity

Journal of medicinal chemistry, 2013-04, Vol.56 (8), p.3207-3216

2013

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Opioid Peptidomimetics: Leads for the Design of Bioavailable Mixed Efficacy μ Opioid Receptor (MOR) Agonist/δ Opioid Receptor (DOR) Antagonist Ligands

Journal of medicinal chemistry, 2013-03, Vol.56 (5), p.2139-2149

2013

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Structure-Based Design and Discovery of New M 2 Receptor Agonists

Journal of medicinal chemistry, 2017-11, Vol.60 (22), p.9239-9250

2017

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Increased agonist affinity at the μ-opioid receptor induced by prolonged agonist exposure

The Journal of neuroscience, 2013-02, Vol.33 (9), p.4118-4127

2013

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A randomized controlled trial to evaluate outcomes of a workplace self-management intervention and an intensive monitoring intervention

Health education research, 2017-06, Vol.32 (3), p.219-232

2017

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Differential Effect of Membrane Cholesterol Removal on μ- and δ-Opioid Receptors: A PARALLEL COMPARISON OF ACUTE AND CHRONIC SIGNALING TO ADENYLYL CYCLASE

The Journal of biological chemistry, 2009-08, Vol.284 (33), p.22108-22122

2009

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Synthesis and evaluation of 4-substituted piperidines and piperazines as balanced affinity μ opioid receptor (MOR) agonist/δ opioid receptor (DOR) antagonist ligands

Bioorganic & medicinal chemistry letters, 2014-01, Vol.24 (2), p.548-551

2014

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Selectively Promiscuous Opioid Ligands: Discovery of High Affinity/Low Efficacy Opioid Ligands with Substantial Nociceptin Opioid Peptide Receptor Affinity

Journal of medicinal chemistry, 2014-05, Vol.57 (10), p.4049-4057

2014

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Binding pathway determines norepinephrine selectivity for the human β1AR over β2AR

Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists

Discovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptor

Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics

Author Correction: Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics

Structure-Based Design and Discovery of New M2 Receptor Agonists

Nucleus accumbens shell excitability is decreased by methamphetamine self-administration and increased by 5-HT2C receptor inverse agonism and agonism

Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane

Structure and selectivity engineering of the M 1 muscarinic receptor toxin complex

Leveraging nonstructural data to predict structures and affinities of protein-ligand complexes

Structure-based discovery of selective positive allosteric modulators of antagonists for the M₂ muscarinic acetylcholine receptor

The Relationship Between the Medical Home and Unmet Needs for Children with Autism Spectrum Disorders

Structure and selectivity engineering of the M1 muscarinic receptor toxin complex

Developmental Monitoring and Referral for Low-Income Children Served by WIC: Program Development and Implementation Outcomes

C7β-Methyl Analogues of the Orvinols: The Discovery of Kappa Opioid Antagonists with Nociceptin/Orphanin FQ Peptide (NOP) Receptor Partial Agonism and Low, or Zero, Efficacy at Mu Opioid Receptors

Consultative Care Coordination Through the Medical Home for CSHCN: A Randomized Controlled Trial

Act Healthy: promoting health behaviors and self-efficacy in the workplace

Orvinols with Mixed Kappa/Mu Opioid Receptor Agonist Activity

Opioid Peptidomimetics: Leads for the Design of Bioavailable Mixed Efficacy μ Opioid Receptor (MOR) Agonist/δ Opioid Receptor (DOR) Antagonist Ligands

Structure-Based Design and Discovery of New M 2 Receptor Agonists

Increased agonist affinity at the μ-opioid receptor induced by prolonged agonist exposure

A randomized controlled trial to evaluate outcomes of a workplace self-management intervention and an intensive monitoring intervention

Differential Effect of Membrane Cholesterol Removal on μ- and δ-Opioid Receptors: A PARALLEL COMPARISON OF ACUTE AND CHRONIC SIGNALING TO ADENYLYL CYCLASE

Synthesis and evaluation of 4-substituted piperidines and piperazines as balanced affinity μ opioid receptor (MOR) agonist/δ opioid receptor (DOR) antagonist ligands

Selectively Promiscuous Opioid Ligands: Discovery of High Affinity/Low Efficacy Opioid Ligands with Substantial Nociceptin Opioid Peptide Receptor Affinity

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