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Molecular control of the NEMO family of ubiquitin-binding proteins

Nature reviews. Molecular cell biology, 2013-10, Vol.14 (10), p.673

2013

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TRAF-associated protein TANK facilitates cross-talk within the IκB kinase family during Toll-like receptor signaling

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (41), p.17093-17098

2011

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The clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases

Biochemical journal, 2015-01, Vol.465 (2), p.271-279

2015

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Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages

Biochemical journal, 2017-02, Vol.474 (4), p.521-537

2017

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The IkappaB kinase family phosphorylates the Parkinson's disease kinase LRRK2 at Ser935 and Ser910 during Toll-like receptor signaling

PloS one, 2012-06, Vol.7 (6), p.e39132

2012

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Novel cross-talk within the IKK family controls innate immunity

Biochemical journal, 2011-02, Vol.434 (1), p.93-104

2011

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Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (42), p.16986-16991

2012

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PGE2 Induces Macrophage IL-10 Production and a Regulatory-like Phenotype via a Protein Kinase A–SIK–CRTC3 Pathway

The Journal of immunology (1950), 2013-01, Vol.190 (2), p.565-577

2013

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Myosin II and mechanotransduction: a balancing act

Trends in cell biology, 2007-04, Vol.17 (4), p.178-186

2007

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alpha-kinase family: an exceptional branch on the protein kinase tree

Cellular and molecular life sciences : CMLS, 2010-03, Vol.67 (6), p.875-890

2010

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TRPM7, a novel regulator of actomyosin contractility and cell adhesion

The EMBO journal, 2006-01, Vol.25 (2), p.290-301

2006

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Activation of TRPM7 Channels by Phospholipase C-coupled Receptor Agonists

The Journal of biological chemistry, 2007-01, Vol.282 (1), p.232-239

2007

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The NEDD8 E3 ligase DCNL5 is phosphorylated by IKK alpha during Toll-like receptor activation

PloS one, 2018-06, Vol.13 (6), p.e0199197-e0199197

2018

Volltextzugriff (PDF)

Protein kinase networks that limit TLR signalling

Biochemical Society transactions, 2014-02, Vol.42 (1), p.11

Clark, Kristopher

2014

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140 Development of first-in-class ERAP2 inhibitors to modulate the cancer immunopeptidome

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A160-A160

2023

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Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7

PloS one, 2008-03, Vol.3 (3), p.e1876

2008

Volltextzugriff (PDF)

553 First-in-class inhibitors of ERAP1 alter the immunopeptidome of cancer, driving a differentiated T cell response leading to tumor growth inhibition

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A583-A583

2021

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Interplay between TRP channels and the cytoskeleton in health and disease

European journal of cell biology, 2008-09, Vol.87 (8), p.631-640

2008

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Rapid Cycle Evaluation and Adaptation of an Inpatient Tobacco Treatment Service at a U.S. Safety-Net Hospital

Implementation research and practice, 2021-01, Vol.2, p.26334895211041295-26334895211041295

2021

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446 Immunopeptidome changes mediated by a novel ERAP1 inhibitor leads to tumor growth inhibition

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A472-A472

2020

Volltextzugriff (PDF)

An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation

Biochemical journal, 2014-08, Vol.461 (3), p.531-537

2014

Volltextzugriff (PDF)

PGE(2) induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway

The Journal of immunology (1950), 2013-01, Vol.190 (2), p.565

2013

Volltextzugriff (PDF)

Eosinophil degranulation in the allergic lung of mice primarily occurs in the airway lumen

Journal of leukocyte biology, 2004-06, Vol.75 (6), p.1001-1009

2004

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Salt-inducible kinase 2 regulates fibrosis during bleomycin-induced lung injury

The Journal of biological chemistry, 2022-12, Vol.298 (12), p.102644-102644, Article 102644

2022

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Abstract 1715: First in class inhibitors of ERAP1 have the potential to be a transformative immunotherapy in oncology

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1715-1715

2021

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Molecular control of the NEMO family of ubiquitin-binding proteins

TRAF-associated protein TANK facilitates cross-talk within the IκB kinase family during Toll-like receptor signaling

The clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases

Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages

The IkappaB kinase family phosphorylates the Parkinson's disease kinase LRRK2 at Ser935 and Ser910 during Toll-like receptor signaling

Novel cross-talk within the IKK family controls innate immunity

Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages

PGE2 Induces Macrophage IL-10 Production and a Regulatory-like Phenotype via a Protein Kinase A–SIK–CRTC3 Pathway

Myosin II and mechanotransduction: a balancing act

alpha-kinase family: an exceptional branch on the protein kinase tree

TRPM7, a novel regulator of actomyosin contractility and cell adhesion

Activation of TRPM7 Channels by Phospholipase C-coupled Receptor Agonists

The NEDD8 E3 ligase DCNL5 is phosphorylated by IKK alpha during Toll-like receptor activation

Protein kinase networks that limit TLR signalling

140 Development of first-in-class ERAP2 inhibitors to modulate the cancer immunopeptidome

Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7

553 First-in-class inhibitors of ERAP1 alter the immunopeptidome of cancer, driving a differentiated T cell response leading to tumor growth inhibition

Interplay between TRP channels and the cytoskeleton in health and disease

Rapid Cycle Evaluation and Adaptation of an Inpatient Tobacco Treatment Service at a U.S. Safety-Net Hospital

446 Immunopeptidome changes mediated by a novel ERAP1 inhibitor leads to tumor growth inhibition

An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation

PGE(2) induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway

Eosinophil degranulation in the allergic lung of mice primarily occurs in the airway lumen

Salt-inducible kinase 2 regulates fibrosis during bleomycin-induced lung injury

Abstract 1715: First in class inhibitors of ERAP1 have the potential to be a transformative immunotherapy in oncology

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