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Mechanism and Regulation of Cytoplasmic Dynein

Annual review of cell and developmental biology, 2015-11, Vol.31 (1), p.83-108

2015

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Structural basis for the initiation of eukaryotic transcription-coupled DNA repair

Nature (London), 2017-11, Vol.551 (7682), p.653-657

2017

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What Could Go Wrong? A Practical Guide to Single-Particle Cryo-EM: From Biochemistry to Atomic Models

Journal of chemical information and modeling, 2020-05, Vol.60 (5), p.2458-2469

2020

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Antigenic Characterization of the HCMV gH/gL/gO and Pentamer Cell Entry Complexes Reveals Binding Sites for Potently Neutralizing Human Antibodies

PLoS pathogens, 2015-10, Vol.11 (10), p.e1005230-e1005230

2015

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Cloud computing platforms to support cryo-EM structure determination

Trends in biochemical sciences (Amsterdam. Regular ed.), 2022-02, Vol.47 (2), p.103-105

2022

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High-Throughput Cryo-EM Enabled by User-Free Preprocessing Routines

Structure (London), 2020-07, Vol.28 (7), p.858-869.e3

2020

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Miro: A molecular switch at the center of mitochondrial regulation

Protein science, 2020-06, Vol.29 (6), p.1269-1284

2020

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Human TFIID Binds to Core Promoter DNA in a Reorganized Structural State

Cell, 2013-01, Vol.152 (1-2), p.120-131

2013

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Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma

PLoS biology, 2020-12, Vol.18 (12), p.e3001018-e3001018

2020

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Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein

Cell, 2017-09, Vol.170 (6), p.1197-1208.e12

2017

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Structural and biochemical studies of HCMV gH/gL/gO and Pentamer reveal mutually exclusive cell entry complexes

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (6), p.1767-1772

2015

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Kinesin-1 utilizes a hierarchical folding mechanism to promote autoinhibition

Biophysical journal, 2023-02, Vol.122 (3), p.25a-25a

2023

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The HSV-1 pUL37 protein promotes cell invasion by regulating the kinesin-1 motor

Proceedings of the National Academy of Sciences - PNAS, 2024-05, Vol.121 (19), p.e2401341121

2024

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Big data in cryoEM: automated collection, processing and accessibility of EM data

Current opinion in microbiology, 2018-06, Vol.43, p.1-8

2018

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Cryo-EM structure of the human MLL1 core complex bound to the nucleosome

Nature communications, 2019-12, Vol.10 (1), p.5540-5540, Article 5540

2019

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cryoem-cloud-tools: A software platform to deploy and manage cryo-EM jobs in the cloud

Journal of structural biology, 2018-09, Vol.203 (3), p.230-235

2018

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A kinesin-1 variant reveals motor-induced microtubule damage in cells

Current biology, 2022-06, Vol.32 (11), p.2416-2429.e6

2022

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Kinesin-1, -2 and -3 use family-specific mechanochemical strategies to effectively compete with dynein during bidirectional transport

Biophysical journal, 2023-02, Vol.122 (3), p.411a-411a

2023

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Kinesin-1, -2, and -3 motors use family-specific mechanochemical strategies to effectively compete with dynein during bidirectional transport

eLife, 2022-09, Vol.11

2022

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Autoinhibited kinesin-1 adopts a hierarchical folding pattern

eLife, 2023-11, Vol.12

2023

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Molecular determinants for α-tubulin methylation by SETD2

The Journal of biological chemistry, 2021-07, Vol.297 (1), p.100898, Article 100898

2021

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Golgi-associated BICD adaptors couple ER membrane penetration and disassembly of a viral cargo

The Journal of cell biology, 2020-05, Vol.219 (5)

2020

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Low cost, high performance processing of single particle cryo-electron microscopy data in the cloud

eLife, 2015-05, Vol.4

2015

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Building a Data-driven Workflow to Streamline Cryo-EM Data Processing

Microscopy and microanalysis, 2019-08, Vol.25 (S2), p.1366-1367

2019

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Bacterial RNA-free RNase P: Structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P

The Journal of biological chemistry, 2023-11, Vol.299 (11), p.105327, Article 105327

2023

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Mechanism and Regulation of Cytoplasmic Dynein

Structural basis for the initiation of eukaryotic transcription-coupled DNA repair

What Could Go Wrong? A Practical Guide to Single-Particle Cryo-EM: From Biochemistry to Atomic Models

Antigenic Characterization of the HCMV gH/gL/gO and Pentamer Cell Entry Complexes Reveals Binding Sites for Potently Neutralizing Human Antibodies

Cloud computing platforms to support cryo-EM structure determination

High-Throughput Cryo-EM Enabled by User-Free Preprocessing Routines

Miro: A molecular switch at the center of mitochondrial regulation

Human TFIID Binds to Core Promoter DNA in a Reorganized Structural State

Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma

Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein

Structural and biochemical studies of HCMV gH/gL/gO and Pentamer reveal mutually exclusive cell entry complexes

Kinesin-1 utilizes a hierarchical folding mechanism to promote autoinhibition

The HSV-1 pUL37 protein promotes cell invasion by regulating the kinesin-1 motor

Big data in cryoEM: automated collection, processing and accessibility of EM data

Cryo-EM structure of the human MLL1 core complex bound to the nucleosome

cryoem-cloud-tools: A software platform to deploy and manage cryo-EM jobs in the cloud

A kinesin-1 variant reveals motor-induced microtubule damage in cells

Kinesin-1, -2 and -3 use family-specific mechanochemical strategies to effectively compete with dynein during bidirectional transport

Kinesin-1, -2, and -3 motors use family-specific mechanochemical strategies to effectively compete with dynein during bidirectional transport

Autoinhibited kinesin-1 adopts a hierarchical folding pattern

Molecular determinants for α-tubulin methylation by SETD2

Golgi-associated BICD adaptors couple ER membrane penetration and disassembly of a viral cargo

Low cost, high performance processing of single particle cryo-electron microscopy data in the cloud

Building a Data-driven Workflow to Streamline Cryo-EM Data Processing

Bacterial RNA-free RNase P: Structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P

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