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A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

Nature (London), 2020-10, Vol.586 (7830), p.560-566

2020

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Publisher Correction: A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

Nature (London), 2021-02, Vol.590 (7844), p.E22-E22

2021

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Small-Molecule Inhibition of TNF-α

Science (American Association for the Advancement of Science), 2005-11, Vol.310 (5750), p.1022-1025

2005

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In situ assembly of enzyme inhibitors using extended tethering

Nature biotechnology, 2003-03, Vol.21 (3), p.308-314

2003

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Combinatorial Target-Guided Ligand Assembly: Identification of Potent Subtype-Selective c-Src Inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2000-03, Vol.97 (6), p.2419-2424

2000

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Identification of Potent and Selective Small-Molecule Inhibitors of Caspase-3 through the Use of Extended Tethering and Structure-Based Drug Design

Journal of medicinal chemistry, 2002-11, Vol.45 (23), p.5005-5022

2002

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Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors

Bioorganic & medicinal chemistry letters, 2010-07, Vol.20 (14), p.4060-4064

2010

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Sa1636 NON-INVASIVE TESTING IN CHRONIC HEPATITIS D VIRUS (HDV) INFECTION: WHAT WORKS BEST TO RULE OUT CIRRHOSIS?

Gastroenterology (New York, N.Y. 1943), 2024-05, Vol.166 (5), p.S-1607-S-1608

2024

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Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors

Bioorganic & medicinal chemistry, 2008-10, Vol.18 (20), p.5648-5652

2008

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WED-407 Characterization of hepatitis D virus RNA and hepatitis B surface antigen kinetics during pegylated interferon-alphamonotherapy: The D-LIVR study

Journal of hepatology, 2024-06, Vol.80, p.S800-S801

2024

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WED-382 Modeling dual antiviral activity of lonafarnib to explain hepatitis D virus RNA negativity 24 weeks after end of therapy despite RNA positivity at end of therapy: The D-LIVR study

Journal of hepatology, 2024-06, Vol.80, p.S814-S814

2024

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Synthesis of Alkoxylamines by Alkoxide Amination with 3,3‘-Di-tert-butyloxaziridine

Journal of organic chemistry, 1999-09, Vol.64 (18), p.6528-6529

1999

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Modifications of the isonipecotic acid fragment of SNS-032 : Analogs with improved permeability and lower efflux ratio

Bioorganic & medicinal chemistry, 2008-12, Vol.18 (23), p.6236-6239

2008

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A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties

Bioorganic & medicinal chemistry, 2008-11, Vol.18 (21), p.5763-5765

2008

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Clinical features predictive of cirrhosis in a large cohort of patients with chronic hepatitis delta infection- Insights from the D-LIVR trial

Journal of hepatology, 2022-07, Vol.77, p.S300-S301

2022

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Treatment of chronic hepatitis D with peginterferon lambda-the phase 2 LIMT-1 clinical trial

Hepatology (Baltimore, Md.), 2023-06, Vol.77 (6), p.2093-2103

2023

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Mathematical modeling of HDV RNA kinetics suggests high peginterferon Lambda efficacy in blocking viral production: insights from the LIMT-1 study

Journal of hepatology, 2022-07, Vol.77, p.S859

2022

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Strong correlation between HBsAg, ALT and HDV-RNA levels in patients with chronic hepatitis D. Results of phase 3 D-LIVR study

Journal of hepatology, 2022-07, Vol.77, p.S269

2022

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Identification of potent and novel small-molecule inhibitors of caspase-3

Bioorganic & medicinal chemistry letters, 2003-11, Vol.13 (21), p.3651-3655

2003

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Multistep Compositional Remodeling of Supported Lipid Membranes by Interfacially Active Phosphatidylinositol Kinases

Analytical chemistry (Washington), 2016-05, Vol.88 (10), p.5042-5045

2016

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A new dual-targeting real-time RT-PCR assay for hepatitis D virus RNA detection

Diagnostic microbiology and infectious disease, 2018-10, Vol.92 (2), p.112-117

2018

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A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

Publisher Correction: A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

Small-Molecule Inhibition of TNF-α

In situ assembly of enzyme inhibitors using extended tethering

Combinatorial Target-Guided Ligand Assembly: Identification of Potent Subtype-Selective c-Src Inhibitors

Identification of Potent and Selective Small-Molecule Inhibitors of Caspase-3 through the Use of Extended Tethering and Structure-Based Drug Design

Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors

Sa1636 NON-INVASIVE TESTING IN CHRONIC HEPATITIS D VIRUS (HDV) INFECTION: WHAT WORKS BEST TO RULE OUT CIRRHOSIS?

Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors

WED-407 Characterization of hepatitis D virus RNA and hepatitis B surface antigen kinetics during pegylated interferon-alphamonotherapy: The D-LIVR study

WED-382 Modeling dual antiviral activity of lonafarnib to explain hepatitis D virus RNA negativity 24 weeks after end of therapy despite RNA positivity at end of therapy: The D-LIVR study

Synthesis of Alkoxylamines by Alkoxide Amination with 3,3‘-Di-tert-butyloxaziridine

Modifications of the isonipecotic acid fragment of SNS-032 : Analogs with improved permeability and lower efflux ratio

A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties

Peginterferon lambda for the treatment of outpatients with COVID-19: a phase 2, placebo-controlled randomised trial

Clinical features predictive of cirrhosis in a large cohort of patients with chronic hepatitis delta infection- Insights from the D-LIVR trial

Treatment of chronic hepatitis D with peginterferon lambda-the phase 2 LIMT-1 clinical trial

Mathematical modeling of HDV RNA kinetics suggests high peginterferon Lambda efficacy in blocking viral production: insights from the LIMT-1 study

Strong correlation between HBsAg, ALT and HDV-RNA levels in patients with chronic hepatitis D. Results of phase 3 D-LIVR study

Week 48 results of the phase 3 D-LIVR study, a randomized double-blind, placebo-controlled trial evaluating the safety and efficacy of Lonafarnib-boosted with Ritonavir with or without Peginterferon Alfa in patients with chronic hepatitis delta

GS-012 - Week 48 results of the phase 3 D-LIVR study, a randomized double-blind, placebo-controlled trial evaluating the safety and efficacy of Lonafarnib-boosted with Ritonavir with or without Peginterferon Alfa in patients with chronic hepatitis delta

PI4KIIIβ is a therapeutic target in chromosome 1q-amplified lung adenocarcinoma

Identification of potent and novel small-molecule inhibitors of caspase-3

Multistep Compositional Remodeling of Supported Lipid Membranes by Interfacially Active Phosphatidylinositol Kinases

A new dual-targeting real-time RT-PCR assay for hepatitis D virus RNA detection

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