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The human milk oligosaccharides 2’-fucosyllactose and 6’-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling

Pediatric research, 2021-01, Vol.89 (1), p.91-101

2021

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Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis

The Journal of clinical investigation, 2016-02, Vol.126 (2), p.495-508

2016

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A Dynamic Variation of Pulmonary ACE2 Is Required to Modulate Neutrophilic Inflammation in Response to Pseudomonas aeruginosa Lung Infection in Mice

The Journal of immunology (1950), 2019-12, Vol.203 (11), p.3000-3012

2019

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Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors

PloS one, 2013-06, Vol.8 (6), p.e65779-e65779

2013

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The human milk oligosaccharide 2′-fucosyllactose attenuates the severity of experimental necrotising enterocolitis by enhancing mesenteric perfusion in the neonatal intestine

British journal of nutrition, 2016-10, Vol.116 (7), p.1175-1187

2016

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Necrotizing enterocolitis, gut microbes, and sepsis

Gut microbes, 2023-12, Vol.15 (1), p.2221470

2023

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Precision-based modeling approaches for necrotizing enterocolitis

Disease models & mechanisms, 2020-06, Vol.13 (6)

2020

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Maternal aryl hydrocarbon receptor activation protects newborns against necrotizing enterocolitis

Nature communications, 2021-02, Vol.12 (1), p.1042-14, Article 1042

2021

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Mechanisms of gut barrier failure in the pathogenesis of necrotizing enterocolitis: Toll-like receptors throw the switch

Seminars in pediatric surgery, 2013-05, Vol.22 (2), p.76-82

2013

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Mucosa-associated bacterial diversity in necrotizing enterocolitis

PloS one, 2014-09, Vol.9 (9), p.e105046-e105046

2014

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A Critical Role for TLR4 in the Pathogenesis of Necrotizing Enterocolitis by Modulating Intestinal Injury and Repair

Journal of Immunology, 2007-10, Vol.179 (7), p.4808-4820

2007

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Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS–NO–nitrite signaling

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (23), p.9451-9456

2013

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The role of epithelial Toll-like receptor signaling in the pathogenesis of intestinal inflammation

Journal of leukocyte biology, 2008-03, Vol.83 (3), p.493-498

2008

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Toll-like Receptor 4-mediated Endoplasmic Reticulum Stress in Intestinal Crypts Induces Necrotizing Enterocolitis

The Journal of biological chemistry, 2014-04, Vol.289 (14), p.9584-9599

2014

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Intestinal Epithelial TLR-4 Activation Is Required for the Development of Acute Lung Injury after Trauma/Hemorrhagic Shock via the Release of HMGB1 from the Gut

The Journal of immunology (1950), 2015-05, Vol.194 (10), p.4931-4939

2015

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Xenotransplanted human organoids identify transepithelial zinc transport as a key mediator of intestinal adaptation

Nature communications, 2024-10, Vol.15 (1), p.8613-16, Article 8613

2024

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Dysregulated brain-gut axis in the setting of traumatic brain injury: review of mechanisms and anti-inflammatory pharmacotherapies

Journal of neuroinflammation, 2024-05, Vol.21 (1), p.124-124, Article 124

2024

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Novel role for the innate immune receptor Toll-like receptor 4 (TLR4) in the regulation of the Wnt signaling pathway and photoreceptor apoptosis

PloS one, 2012-05, Vol.7 (5), p.e36560-e36560

2012

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Animal models of gastrointestinal and liver diseases. Animal models of necrotizing enterocolitis: pathophysiology, translational relevance, and challenges

American journal of physiology: Gastrointestinal and liver physiology, 2014-06, Vol.306 (11), p.G917-G928

2014

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A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis

The Journal of immunology (1950), 2013-04, Vol.190 (7), p.3541-3551

2013

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Cellular‐specific role of toll‐like receptor 4 in hepatic ischemia‐reperfusion injury in mice

Hepatology (Baltimore, Md.), 2013-07, Vol.58 (1), p.374-387

2013

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Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (28), p.11330-11335

2012

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Genetic Deletion of Toll-Like Receptor 4 on Platelets Attenuates Experimental Pulmonary Hypertension

Circulation research, 2014-05, Vol.114 (10), p.1596-1600

2014

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Bench to bedside — new insights into the pathogenesis of necrotizing enterocolitis

Nature reviews. Gastroenterology & hepatology, 2022-07, Vol.19 (7), p.468-479

2022

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Innate Immune Signaling in the Pathogenesis of Necrotizing Enterocolitis

Clinical & developmental immunology, 2013-01, Vol.2013 (2013), p.1-10

2013

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The human milk oligosaccharides 2’-fucosyllactose and 6’-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling

Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis

A Dynamic Variation of Pulmonary ACE2 Is Required to Modulate Neutrophilic Inflammation in Response to Pseudomonas aeruginosa Lung Infection in Mice

Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors

The human milk oligosaccharide 2′-fucosyllactose attenuates the severity of experimental necrotising enterocolitis by enhancing mesenteric perfusion in the neonatal intestine

Necrotizing enterocolitis, gut microbes, and sepsis

Precision-based modeling approaches for necrotizing enterocolitis

Maternal aryl hydrocarbon receptor activation protects newborns against necrotizing enterocolitis

Mechanisms of gut barrier failure in the pathogenesis of necrotizing enterocolitis: Toll-like receptors throw the switch

Mucosa-associated bacterial diversity in necrotizing enterocolitis

A Critical Role for TLR4 in the Pathogenesis of Necrotizing Enterocolitis by Modulating Intestinal Injury and Repair

Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS–NO–nitrite signaling

The role of epithelial Toll-like receptor signaling in the pathogenesis of intestinal inflammation

Toll-like Receptor 4-mediated Endoplasmic Reticulum Stress in Intestinal Crypts Induces Necrotizing Enterocolitis

Intestinal Epithelial TLR-4 Activation Is Required for the Development of Acute Lung Injury after Trauma/Hemorrhagic Shock via the Release of HMGB1 from the Gut

Xenotransplanted human organoids identify transepithelial zinc transport as a key mediator of intestinal adaptation

Dysregulated brain-gut axis in the setting of traumatic brain injury: review of mechanisms and anti-inflammatory pharmacotherapies

Novel role for the innate immune receptor Toll-like receptor 4 (TLR4) in the regulation of the Wnt signaling pathway and photoreceptor apoptosis

Animal models of gastrointestinal and liver diseases. Animal models of necrotizing enterocolitis: pathophysiology, translational relevance, and challenges

A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis

Cellular‐specific role of toll‐like receptor 4 in hepatic ischemia‐reperfusion injury in mice

Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium

Genetic Deletion of Toll-Like Receptor 4 on Platelets Attenuates Experimental Pulmonary Hypertension

Bench to bedside — new insights into the pathogenesis of necrotizing enterocolitis

Innate Immune Signaling in the Pathogenesis of Necrotizing Enterocolitis

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