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A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy

Nature communications, 2015-03, Vol.6 (1), p.6645, Article 6645

2015

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Stromal features are predictive of disease mortality in oral cancer patients

The Journal of pathology, 2011-03, Vol.223 (4), p.470-481

2011

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A vector-encoded bispecific killer engager to harness virus-activated NK cells as anti-tumor effectors

Cell death & disease, 2023-02, Vol.14 (2), p.104-104, Article 104

2023

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Acid-cleavable thiomaleamic acid linker for homogeneous antibody-drug conjugation

Chemical communications (Cambridge, England), 2013-01, Vol.49 (74), p.8187-8189

2013

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Production of recombinant protein in Pichia pastoris by fermentation

Nature protocols, 2006-08, Vol.1 (2), p.1006-1021

2006

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The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity

Cancer Immunology, Immunotherapy, 2017-11, Vol.66 (11), p.1425-1436

2017

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Tuning the Hydrolytic Stability of Next Generation Maleimide Cross-Linkers Enables Access to Albumin-Antibody Fragment Conjugates and tri-scFvs

Bioconjugate chemistry, 2018-02, Vol.29 (2), p.486-492

2018

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A Phase I Study of Single Administration of Antibody-Directed Enzyme Prodrug Therapy with the Recombinant Anti–Carcinoembryonic Antigen Antibody-Enzyme Fusion Protein MFECP1 and a Bis-Iodo Phenol Mustard Prodrug

Clinical cancer research, 2006-11, Vol.12 (21), p.6509-6516

2006

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Next generation maleimides enable the controlled assembly of antibody-drug conjugates via native disulfide bond bridging

Organic & biomolecular chemistry, 2014-10, Vol.12 (37), p.7261-7269

2014

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Anti-CD45 PBD-based antibody-drug conjugates are effective targeted conditioning agents for gene therapy and stem cell transplant

Molecular therapy, 2024-06, Vol.32 (6), p.1672-1686

2024

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Clearance mechanism of a mannosylated antibody-enzyme fusion protein used in experimental cancer therapy

Glycobiology (Oxford), 2007-01, Vol.17 (1), p.36-45

2007

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Sustained Tumor Regression of Human Colorectal Cancer Xenografts Using a Multifunctional Mannosylated Fusion Protein in Antibody-Directed Enzyme Prodrug Therapy

Clinical cancer research, 2005-01, Vol.11 (2), p.814-825

2005

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Homogeneous Bispecifics by Disulfide Bridging

Bioconjugate chemistry, 2014-08, Vol.25 (8), p.1395-1401

2014

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Antibody-drug conjugates - a perfect synergy

Expert opinion on biological therapy, 2012-09, Vol.12 (9), p.1191-1206

2012

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Aryloxymaleimides for cysteine modification, disulfide bridging and the dual functionalization of disulfide bonds

Chemical communications (Cambridge, England), 2014-07, Vol.50 (54), p.7139-7142

2014

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Preclinical evaluation of a novel CEA‐targeting near‐infrared fluorescent tracer delineating colorectal and pancreatic tumors

International journal of cancer, 2015-10, Vol.137 (8), p.1910-1920

2015

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Targeted photodynamic therapy with multiply‐loaded recombinant antibody fragments

International journal of cancer, 2008-03, Vol.122 (5), p.1155-1163

2008

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Homogeneous antibody fragment conjugation by disulfide bridging introduces 'spinostics'

Scientific reports, 2013-03, Vol.3 (1), p.1525-1525, Article 1525

2013

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Nanoparticles functionalised with recombinant single chain Fv antibody fragments (scFv) for the magnetic resonance imaging of cancer cells

Biomaterials, 2010-02, Vol.31 (6), p.1307-1315

2010

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Glycoengineering Approach to Half-Life Extension of Recombinant Biotherapeutics

Bioconjugate chemistry, 2012-08, Vol.23 (8), p.1524-1533

2012

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Antibody-–enzyme fusion proteins for cancer therapy

Immunotherapy, 2011-02, Vol.3 (2), p.193-211

2011

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The role of extracellular spacer regions in the optimal design of chimeric immune receptors: evaluation of four different scFvs and antigens

Journal of immunotherapy (1997), 2005-05, Vol.28 (3), p.203

2005

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A Phase I Trial of Radioimmunotherapy with 131I-A5B7 Anti-CEA Antibody in Combination with Combretastatin-A4-Phosphate in Advanced Gastrointestinal Carcinomas

Clinical cancer research, 2009-07, Vol.15 (13), p.4484-4492

2009

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Targeted Retroviral Infection of Tumor Cells by Receptor Cooperation

Journal of Virology, 2003-02, Vol.77 (4), p.2753-2756

2003

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Antibody Engineering & Therapeutics 2016: The Antibody Society's annual meeting, December 11-15, 2016, San Diego, CA

mAbs, 2016-11, Vol.8 (8), p.1425-1434

2016

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A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy

Stromal features are predictive of disease mortality in oral cancer patients

A vector-encoded bispecific killer engager to harness virus-activated NK cells as anti-tumor effectors

Acid-cleavable thiomaleamic acid linker for homogeneous antibody-drug conjugation

Production of recombinant protein in Pichia pastoris by fermentation

The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity

Tuning the Hydrolytic Stability of Next Generation Maleimide Cross-Linkers Enables Access to Albumin-Antibody Fragment Conjugates and tri-scFvs

A Phase I Study of Single Administration of Antibody-Directed Enzyme Prodrug Therapy with the Recombinant Anti–Carcinoembryonic Antigen Antibody-Enzyme Fusion Protein MFECP1 and a Bis-Iodo Phenol Mustard Prodrug

Next generation maleimides enable the controlled assembly of antibody-drug conjugates via native disulfide bond bridging

Anti-CD45 PBD-based antibody-drug conjugates are effective targeted conditioning agents for gene therapy and stem cell transplant

Clearance mechanism of a mannosylated antibody-enzyme fusion protein used in experimental cancer therapy

Sustained Tumor Regression of Human Colorectal Cancer Xenografts Using a Multifunctional Mannosylated Fusion Protein in Antibody-Directed Enzyme Prodrug Therapy

Homogeneous Bispecifics by Disulfide Bridging

Antibody-drug conjugates - a perfect synergy

Aryloxymaleimides for cysteine modification, disulfide bridging and the dual functionalization of disulfide bonds

Preclinical evaluation of a novel CEA‐targeting near‐infrared fluorescent tracer delineating colorectal and pancreatic tumors

Targeted photodynamic therapy with multiply‐loaded recombinant antibody fragments

Homogeneous antibody fragment conjugation by disulfide bridging introduces 'spinostics'

Nanoparticles functionalised with recombinant single chain Fv antibody fragments (scFv) for the magnetic resonance imaging of cancer cells

Glycoengineering Approach to Half-Life Extension of Recombinant Biotherapeutics

Antibody-–enzyme fusion proteins for cancer therapy

The role of extracellular spacer regions in the optimal design of chimeric immune receptors: evaluation of four different scFvs and antigens

A Phase I Trial of Radioimmunotherapy with 131I-A5B7 Anti-CEA Antibody in Combination with Combretastatin-A4-Phosphate in Advanced Gastrointestinal Carcinomas

Targeted Retroviral Infection of Tumor Cells by Receptor Cooperation

Antibody Engineering & Therapeutics 2016: The Antibody Society's annual meeting, December 11-15, 2016, San Diego, CA

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