UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 71

Sortiert nach

The effects of FAAH inhibition on the neural basis of anxiety-related processing in healthy male subjects: a randomized clinical trial

Neuropsychopharmacology (New York, N.Y.), 2021-04, Vol.46 (5), p.1011-1019

2021

Link zum Volltext

Verfügbarkeit prüfen

Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia

The Journal of pharmacology and experimental therapeutics, 2015-09, Vol.354 (3), p.471

2015

Link zum Volltext

Verfügbarkeit prüfen

Effects of the selective orexin-2 receptor antagonist JNJ-48816274 on sleep initiated in the circadian wake maintenance zone: a randomised trial

Neuropsychopharmacology (New York, N.Y.), 2022-02, Vol.47 (3), p.719-727

2022

Link zum Volltext

Verfügbarkeit prüfen

Selective Blockade of the Capsaicin Receptor TRPV1 Attenuates Bone Cancer Pain

The Journal of neuroscience, 2005-03, Vol.25 (12), p.3126-3131

2005

Link zum Volltext

Verfügbarkeit prüfen

Selective inhibition of peripheral cathepsin S reverses tactile allodynia following peripheral nerve injury in mouse

European journal of pharmacology, 2020-08, Vol.880, p.173171, Article 173171

2020

Link zum Volltext

Verfügbarkeit prüfen

Neuronal Hyperpolarization-Activated Pacemaker Channels Drive Neuropathic Pain

The Journal of neuroscience, 2003-02, Vol.23 (4), p.1169-1178

2003

Link zum Volltext

Verfügbarkeit prüfen

Sodium Channel Blockers for the Treatment of Neuropathic Pain

Neurotherapeutics, 2009-10, Vol.6 (4), p.663-678

2009

Link zum Volltext

Verfügbarkeit prüfen

Two TRPV1 receptor antagonists are effective in two different experimental models of migraine

Journal of headache and pain, 2015-06, Vol.16 (1), p.57-57, Article 57

2015

Link zum Volltext

Verfügbarkeit prüfen

Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms

British journal of pharmacology, 2006-05, Vol.148 (1), p.102-113

2006

Link zum Volltext

Verfügbarkeit prüfen

Identification and Biological Evaluation of 4-(3-Trifluoromethylpyridin-2-yl)piperazine-1-carboxylic Acid (5-Trifluoromethylpyridin-2-yl)amide, a High Affinity TRPV1 (VR1) Vanilloid Receptor Antagonist

Journal of medicinal chemistry, 2005-03, Vol.48 (6), p.1857-1872

2005

Link zum Volltext

Verfügbarkeit prüfen

Preclinical Characterization of the FAAH Inhibitor JNJ-42165279

ACS medicinal chemistry letters, 2015-12, Vol.6 (12), p.1204-1208

2015

Link zum Volltext

Verfügbarkeit prüfen

Activation of TRPA1 by Farnesyl Thiosalicylic Acid

Molecular pharmacology, 2008-04, Vol.73 (4), p.1225-1234

2008

Link zum Volltext

Verfügbarkeit prüfen

Pharmacology and antitussive efficacy of 4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic acid (5-trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a transient receptor potential vanilloid 1 antagonist in guinea pigs

The Journal of pharmacology and experimental therapeutics, 2007-11, Vol.323 (2), p.665

2007

Link zum Volltext

Verfügbarkeit prüfen

Heteroarylureas with spirocyclic diamine cores as inhibitors of fatty acid amide hydrolase

Bioorganic & medicinal chemistry letters, 2014-02, Vol.24 (3), p.737-741

2014

Link zum Volltext

Verfügbarkeit prüfen

A Phase 1 First‐in‐Human Pharmacokinetic and Pharmacodynamic Study of JNJ‐64264681, a Covalent Inhibitor of Bruton's Tyrosine Kinase

Clinical pharmacology in drug development, 2023-06, Vol.12 (6), p.611-624

2023

Link zum Volltext

Verfügbarkeit prüfen

Biochemical and Biological Properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a Mechanism-Based Inhibitor of Fatty Acid Amide Hydrolase

Anesthesia and analgesia, 2009, Vol.108 (1), p.316-329

2009

Link zum Volltext

Verfügbarkeit prüfen

1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase

Bioorganic & medicinal chemistry letters, 2014-03, Vol.24 (5), p.1280-1284

2014

Link zum Volltext

Verfügbarkeit prüfen

The discovery and preclinical characterization of 6-chloro-N-(2-(4,4-difluoropiperidin-1-yl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)quinoline-5-carboxamide based P2X7 antagonists

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (19), p.4781-4784

2016

Link zum Volltext

Verfügbarkeit prüfen

The SAR of brain penetration for a series of heteroaryl urea FAAH inhibitors

Bioorganic & medicinal chemistry letters, 2016-07, Vol.26 (13), p.3109-3114

2016

Link zum Volltext

Verfügbarkeit prüfen

Hyperpolarization-Activated, Cation-Nonselective, Cyclic Nucleotide-Modulated Channel Blockade Alleviates Mechanical Allodynia and Suppresses Ectopic Discharge in Spinal Nerve Ligated Rats

The journal of pain, 2005-07, Vol.6 (7), p.417-424

2005

Link zum Volltext

Verfügbarkeit prüfen

Characterization of 2-(2,6-dichloro-benzyl)-thiazolo[5,4- d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine (JNJ-39729209) as a novel TRPV1 antagonist

European journal of pharmacology, 2011-08, Vol.663 (1), p.40-50

2011

Link zum Volltext

Verfügbarkeit prüfen

Discovery of a novel series of selective HCN1 blockers

Bioorganic & medicinal chemistry letters, 2011-09, Vol.21 (18), p.5197-5201

2011

Link zum Volltext

Verfügbarkeit prüfen

Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine

Pain (Amsterdam), 1996-12, Vol.68 (2), p.293-299

1996

Link zum Volltext

Verfügbarkeit prüfen

Vincristine-induced allodynia in the rat

Pain (Amsterdam), 2001-07, Vol.93 (1), p.69-76

2001

Link zum Volltext

Verfügbarkeit prüfen

HCN channels as targets for drug discovery

Combinatorial chemistry & high throughput screening, 2009-01, Vol.12 (1), p.64

2009

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 71

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(66)
Mit Volltextzugriff
(64)

Publikationsform

Artikel
(68)
Buchkapitel
(3)

Sprache

Englisch
(71)
Japanisch
(15)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

The effects of FAAH inhibition on the neural basis of anxiety-related processing in healthy male subjects: a randomized clinical trial

Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia

Effects of the selective orexin-2 receptor antagonist JNJ-48816274 on sleep initiated in the circadian wake maintenance zone: a randomised trial

Selective Blockade of the Capsaicin Receptor TRPV1 Attenuates Bone Cancer Pain

Selective inhibition of peripheral cathepsin S reverses tactile allodynia following peripheral nerve injury in mouse

Neuronal Hyperpolarization-Activated Pacemaker Channels Drive Neuropathic Pain

Sodium Channel Blockers for the Treatment of Neuropathic Pain

Two TRPV1 receptor antagonists are effective in two different experimental models of migraine

Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms

Identification and Biological Evaluation of 4-(3-Trifluoromethylpyridin-2-yl)piperazine-1-carboxylic Acid (5-Trifluoromethylpyridin-2-yl)amide, a High Affinity TRPV1 (VR1) Vanilloid Receptor Antagonist

Preclinical Characterization of the FAAH Inhibitor JNJ-42165279

Activation of TRPA1 by Farnesyl Thiosalicylic Acid

Pharmacology and antitussive efficacy of 4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic acid (5-trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a transient receptor potential vanilloid 1 antagonist in guinea pigs

Heteroarylureas with spirocyclic diamine cores as inhibitors of fatty acid amide hydrolase

A Phase 1 First‐in‐Human Pharmacokinetic and Pharmacodynamic Study of JNJ‐64264681, a Covalent Inhibitor of Bruton's Tyrosine Kinase

Biochemical and Biological Properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a Mechanism-Based Inhibitor of Fatty Acid Amide Hydrolase

1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase

The discovery and preclinical characterization of 6-chloro-N-(2-(4,4-difluoropiperidin-1-yl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)quinoline-5-carboxamide based P2X7 antagonists

The SAR of brain penetration for a series of heteroaryl urea FAAH inhibitors

Hyperpolarization-Activated, Cation-Nonselective, Cyclic Nucleotide-Modulated Channel Blockade Alleviates Mechanical Allodynia and Suppresses Ectopic Discharge in Spinal Nerve Ligated Rats

Characterization of 2-(2,6-dichloro-benzyl)-thiazolo[5,4- d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine (JNJ-39729209) as a novel TRPV1 antagonist

Discovery of a novel series of selective HCN1 blockers

Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine

Vincristine-induced allodynia in the rat

HCN channels as targets for drug discovery

Suchergebnisse filtern