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Molecular mechanisms of neurotoxin action on voltage-gated sodium channels

Biochimie, 2000-09, Vol.82 (9), p.883-892

2000

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Canaux sodiques et canalopathies : douleurs neuropathiques, épilepsies, migraine

Douleur et analgésie, 2016-12, Vol.29 (4), p.212-220

2016

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Depolarization Differentially Affects Allosteric Modulation by Neurotoxins of Scorpion α‐Toxin Binding on Voltage‐Gated Sodium Channels

Journal of neurochemistry, 1998-03, Vol.70 (3), p.1217-1226

1998

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Voltage Sensor–Trapping: Enhanced Activation of Sodium Channels by β-Scorpion Toxin Bound to the S3–S4 Loop in Domain II

Neuron (Cambridge, Mass.), 1998-10, Vol.21 (4), p.919-931

1998

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Rare coding variants in genes encoding GABA A receptors in genetic generalised epilepsies: an exome-based case-control study

Lancet neurology, 2018-08, Vol.17 (8), p.699

2018

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Network topology of NaV1.7 mutations in sodium channel-related painful disorders

BMC systems biology, 2017-02, Vol.11 (1), p.28, Article 28

2017

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Neutralization of gating charges in domain II of the sodium channel alpha subunit enhances voltage-sensor trapping by a beta-scorpion toxin

The Journal of general physiology, 2001-09, Vol.118 (3), p.291-302

2001

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Scorpion toxins affecting sodium current inactivation bind to distinct homologous receptor sites on rat brain and insect sodium channels

The Journal of biological chemistry, 1996-04, Vol.271 (14), p.8034-8045

1996

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Tetrodotoxin Reverses Brevetoxin Allosteric Inhibition of Scorpion α-Toxin Binding on Rat Brain Sodium Channels

The Journal of biological chemistry, 1996-08, Vol.271 (31), p.18329-18332

1996

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Toxin III from Leiurus quinquestriatus quinquestriatus: A specific probe for receptor site 3 on insect sodium channels

Insect biochemistry and molecular biology, 1997-06, Vol.27 (6), p.523-528

1997

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Voltage-gated ion channels and gating modifier toxins

Toxicon (Oxford), 2007-02, Vol.49 (2), p.124-141

2007

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Bot IT2: a new scorpion toxin to study receptor site on insect sodium channels

FEBS letters, 1997-03, Vol.405 (1), p.77-80

1997

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New toxins acting on sodium channels from the scorpion Leiurus quinquestriatus hebraeus suggest a clue to mammalian vs insect selectivity

Toxicon (Oxford), 1998-08, Vol.36 (8), p.1141-1154

1998

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δ-Atracotoxins from Australian funnel-web spiders compete with scorpion α-toxin binding on both rat brain and insect sodium channels

FEBS letters, 1998-11, Vol.439 (3), p.246-252

1998

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Scorpion α-like toxins, toxic to both mammals and insects, differentially interact with receptor site 3 on voltage-gated sodium channels in mammals and insects

The European journal of neuroscience, 1999-03, Vol.11 (3), p.975-985

1999

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α-Scorpion Toxins Binding on Rat Brain and Insect Sodium Channels Reveal Divergent Allosteric Modulations by Brevetoxin and Veratridine (∗)

The Journal of biological chemistry, 1995-06, Vol.270 (25), p.15153-15161

1995

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β‐Scorpion toxin effects suggest electrostatic interactions in domain II of voltage‐dependent sodium channels

The Journal of physiology, 2005-10, Vol.568 (1), p.13-30

2005

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A gain-of-function sodium channel β 2-subunit mutation in painful diabetic neuropathy

Molecular pain, 2019-05, Vol.15, p.174480691984980

2019

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Purification, structure and activity of three insect toxins from Buthus occitanus tunetanus venom

Toxicon (Oxford), 1997-03, Vol.35 (3), p.365-382

1997

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Role of lysine and tryptophan residues in the biological activity of toxin VII (Ts γ) from the scorpion Tityus serrulatus

European Journal of Biochemistry, 1999-02, Vol.260 (1), p.76-86

1999

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Biochemical and pharmacological characterization of a depressant insect toxin from the venom of the scorpion Buthacus arenicola

European Journal of Biochemistry, 1997-01, Vol.243 (1/2), p.93-99

1997

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Molecular cloning and functional expression of the alpha-scorpion toxin BotIII: pivotal role of the C-terminal region for its interaction with voltage-dependent sodium channels

Peptides (New York, N.Y. : 1980), 2004-02, Vol.25 (2), p.151-161

2004

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Unexpected allosteric modulation of neurotoxin binding on voltage-gated sodium channels

Toxicon (Oxford), 1997-12, Vol.35 (12), p.1661-1662

1997

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Identification of structural elements of a scorpion alpha-neurotoxin important for receptor site recognition

The Journal of biological chemistry, 1997-06, Vol.272 (23), p.14810-14816

1997

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Production of active, insect‐specific scorpion neurotoxin in yeast

European Journal of Biochemistry, 1994-07, Vol.223 (2), p.637-645

1994

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Molecular mechanisms of neurotoxin action on voltage-gated sodium channels

Canaux sodiques et canalopathies : douleurs neuropathiques, épilepsies, migraine

Depolarization Differentially Affects Allosteric Modulation by Neurotoxins of Scorpion α‐Toxin Binding on Voltage‐Gated Sodium Channels

Voltage Sensor–Trapping: Enhanced Activation of Sodium Channels by β-Scorpion Toxin Bound to the S3–S4 Loop in Domain II

Rare coding variants in genes encoding GABA A receptors in genetic generalised epilepsies: an exome-based case-control study

Network topology of NaV1.7 mutations in sodium channel-related painful disorders

Neutralization of gating charges in domain II of the sodium channel alpha subunit enhances voltage-sensor trapping by a beta-scorpion toxin

Scorpion toxins affecting sodium current inactivation bind to distinct homologous receptor sites on rat brain and insect sodium channels

Tetrodotoxin Reverses Brevetoxin Allosteric Inhibition of Scorpion α-Toxin Binding on Rat Brain Sodium Channels

Toxin III from Leiurus quinquestriatus quinquestriatus: A specific probe for receptor site 3 on insect sodium channels

Voltage-gated ion channels and gating modifier toxins

Bot IT2: a new scorpion toxin to study receptor site on insect sodium channels

New toxins acting on sodium channels from the scorpion Leiurus quinquestriatus hebraeus suggest a clue to mammalian vs insect selectivity

δ-Atracotoxins from Australian funnel-web spiders compete with scorpion α-toxin binding on both rat brain and insect sodium channels

Scorpion α-like toxins, toxic to both mammals and insects, differentially interact with receptor site 3 on voltage-gated sodium channels in mammals and insects

α-Scorpion Toxins Binding on Rat Brain and Insect Sodium Channels Reveal Divergent Allosteric Modulations by Brevetoxin and Veratridine (∗)

β‐Scorpion toxin effects suggest electrostatic interactions in domain II of voltage‐dependent sodium channels

A gain-of-function sodium channel β 2-subunit mutation in painful diabetic neuropathy

Purification, structure and activity of three insect toxins from Buthus occitanus tunetanus venom

Role of lysine and tryptophan residues in the biological activity of toxin VII (Ts γ) from the scorpion Tityus serrulatus

Biochemical and pharmacological characterization of a depressant insect toxin from the venom of the scorpion Buthacus arenicola

Molecular cloning and functional expression of the alpha-scorpion toxin BotIII: pivotal role of the C-terminal region for its interaction with voltage-dependent sodium channels

Unexpected allosteric modulation of neurotoxin binding on voltage-gated sodium channels

Identification of structural elements of a scorpion alpha-neurotoxin important for receptor site recognition

Production of active, insect‐specific scorpion neurotoxin in yeast

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