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Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance

Cell death and differentiation, 2016-05, Vol.23 (5), p.759-775

2016

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Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A

Blood cancer journal (New York), 2013-07, Vol.3 (7), p.e128-e128

2013

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253 INVITED Exploring translation initiation as a therapeutic target

European journal of cancer supplements, 2008, Vol.6 (12), p.83-83

2008

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Investigating the Substrate Specificity and Oligomerisation of the Leader Protease of Foot and Mouth Disease Virus using NMR

Journal of molecular biology, 2007-11, Vol.373 (4), p.1071-1087

2007

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Foot-and-mouth disease virus leader proteinase: involvement of C-terminal residues in self-processing and cleavage of eIF4GI

The Journal of biological chemistry, 2001-09, Vol.276 (38), p.35473-35481

2001

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Foot-and-Mouth Disease Virus Leader Proteinase: Specificity at the P2 and P3 Positions and Comparison with Other Papain-like Enzymes

Biochemistry (Easton), 2004-09, Vol.43 (36), p.11482-11490

2004

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Abstracts of the 52nd Workshop for Pediatric Research

Molecular and cellular pediatrics, 2017-05, Vol.4 (1), p.1-9

2017

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Structural conservation of druggable hot spots in protein–protein interfaces

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (33), p.13528-13533

2011

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Repurposing CRISPR/Cas9 for in situ functional assays

Genes & development, 2013-12, Vol.27 (23), p.2602-2614

2013

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CRISPR-Mediated Drug-Target Validation Reveals Selective Pharmacological Inhibition of the RNA Helicase, eIF4A

Cell reports (Cambridge), 2016-06, Vol.15 (11), p.2340-2347

2016

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Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (3), p.1046-1051

2011

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Blocking eIF4E-eIF4G Interaction as a Strategy To Impair Coronavirus Replication

Journal of Virology, 2011-07, Vol.85 (13), p.6381-6389

2011

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Constrained fits with non-Gaussian distributions

Journal of physics. Conference series, 2016-10, Vol.762 (1), p.12037

2016

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Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides

Nature chemistry, 2017-11, Vol.9 (11), p.1140-1149

2017

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c-Myc and eIF4F are components of a feedforward loop that links transcription and translation

Cancer research (Chicago, Ill.), 2008-07, Vol.68 (13), p.5326-5334

2008

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Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells

ACS central science, 2024-08, Vol.10 (8), p.1640-1656

2024

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Isolation and identification of bacteriocinogenic strain of Lactobacillus plantarum with potential beneficial properties from donkey milk

Journal of applied microbiology, 2013-06, Vol.114 (6), p.1793-1809

2013

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A New Natural Product Analog of Blasticidin S Reveals Cellular Uptake Facilitated by the NorA Multidrug Transporter

Antimicrobial agents and chemotherapy, 2017-06, Vol.61 (6)

2017

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Obatoclax is a direct and potent antagonist of membrane-restricted Mcl-1 and is synthetic lethal with treatment that induces Bim

BMC cancer, 2015-08, Vol.15 (1), p.568, Article 568

2015

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5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells

European journal of medicinal chemistry, 2016-09, Vol.120, p.313-328

2016

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Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival

Cancer research (Chicago, Ill.), 2012-02, Vol.72 (3), p.747-756

2012

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Antibacterial and anticandidal activity of Tylosema esculentum (marama) extracts

South African Journal of Science, 2011-03, Vol.107 (3/4), p.79-89

2011

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The effect of depurinized milk draught diet on rat serum uric acid, lipid status and haematological parameters

Journal of animal physiology and animal nutrition, 2012-08, Vol.96 (4), p.640-647

2012

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Tylosema esculentum extractives and their bioactivity

Bioorganic & medicinal chemistry, 2011-09, Vol.19 (17), p.5225-5230

2011

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Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance

Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A

253 INVITED Exploring translation initiation as a therapeutic target

Investigating the Substrate Specificity and Oligomerisation of the Leader Protease of Foot and Mouth Disease Virus using NMR

Foot-and-mouth disease virus leader proteinase: involvement of C-terminal residues in self-processing and cleavage of eIF4GI

Foot-and-Mouth Disease Virus Leader Proteinase: Specificity at the P2 and P3 Positions and Comparison with Other Papain-like Enzymes

Abstracts of the 52nd Workshop for Pediatric Research

CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary

Structural conservation of druggable hot spots in protein–protein interfaces

Repurposing CRISPR/Cas9 for in situ functional assays

CRISPR-Mediated Drug-Target Validation Reveals Selective Pharmacological Inhibition of the RNA Helicase, eIF4A

Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F

Blocking eIF4E-eIF4G Interaction as a Strategy To Impair Coronavirus Replication

Constrained fits with non-Gaussian distributions

Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides

c-Myc and eIF4F are components of a feedforward loop that links transcription and translation

Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells

Isolation and identification of bacteriocinogenic strain of Lactobacillus plantarum with potential beneficial properties from donkey milk

A New Natural Product Analog of Blasticidin S Reveals Cellular Uptake Facilitated by the NorA Multidrug Transporter

Obatoclax is a direct and potent antagonist of membrane-restricted Mcl-1 and is synthetic lethal with treatment that induces Bim

5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells

Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival

Antibacterial and anticandidal activity of Tylosema esculentum (marama) extracts

The effect of depurinized milk draught diet on rat serum uric acid, lipid status and haematological parameters

Tylosema esculentum extractives and their bioactivity

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