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[3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A2B receptors

Biochemical pharmacology, 2004-07, Vol.68 (2), p.305-312

2004

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Discovery of VU2957 (Valiglurax): An mGlu 4 Positive Allosteric Modulator Evaluated as a Preclinical Candidate for the Treatment of Parkinson's Disease

ACS medicinal chemistry letters, 2019-03, Vol.10 (3), p.255-260

2019

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Discovery of VU2957 (Valiglurax): An mGlu4 Positive Allosteric Modulator Evaluated as a Preclinical Candidate for the Treatment of Parkinson’s Disease

ACS medicinal chemistry letters, 2019-03, Vol.10 (3), p.255-260

2019

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OSI-930 : A novel selective inhibitor of kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models

Cancer research (Chicago, Ill.), 2006-01, Vol.66 (2), p.1015-1024

2006

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Glucokinase-activating ureas

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (5), p.1501-1504

2005

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A practical solid phase synthesis of quinazoline-2,4-diones

Tetrahedron letters, 1998-10, Vol.39 (40), p.7235-7238

1998

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Leporin B: a novel hexokinase II gene inducing agent from an unidentified fungus

Bioorganic & medicinal chemistry letters, 2003-04, Vol.13 (8), p.1433-1435

2003

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Potent and selective [2-imidazol-1-yl-2-(6-alkoxy-naphthalen-2-yl)-1-methyl-ethyl]-dimethyl-amines as retinoic acid metabolic blocking agents (RAMBAs)

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (6), p.1669-1673

2005

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3-[6-(2-Dimethylamino-1-imidazol-1-yl-butyl)-naphthalen-2-yloxy]-2,2-dimethyl-propionic acid as a highly potent and selective retinoic acid metabolic blocking agent

Bioorganic & medicinal chemistry letters, 2006-05, Vol.16 (10), p.2729-2733

2006

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Development and kilogram-scale synthesis of mGlu5 negative allosteric modulator VU0424238 (auglurant)

Tetrahedron letters, 2017-09, Vol.58 (36), p.3554-3558

2017

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Study of noncovalent enzyme—inhibitor complexes and metal binding stoichiometry of matrilysin by electrospray ionization mass spectrometry

Journal of the American Society for Mass Spectrometry, 1995-11, Vol.6 (11), p.1105-1111

1995

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Synthesis of Functionalized Pyridones via Palladium Catalyzed Cross Coupling Reactions

Synlett, 1998-12, Vol.1998 (12), p.1408-1410

1998

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Matrilysin-inhibitor complexes: common themes among metalloproteases

Biochemistry (Easton), 1995-05, Vol.34 (20), p.6602-6610

1995

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Inactivation of a Cytosolic Phospholipase A2 by Thiol-Modifying Reagents: Cysteine Residues as Potential Targets of Phospholipase A2

Biochemistry (Easton), 1994-07, Vol.33 (28), p.8594-8603

1994

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Intriguing structure-activity relations underlie the potent inhibition of HIV protease by norstatine-based peptides

Journal of medicinal chemistry, 1992-04, Vol.35 (7), p.1318-1320

1992

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Crystal structures of matrilysin-inhibitor complexes

Biochemistry (Easton), 1995-05, Vol.34 (20), p.6602-6610

1995

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Practical synthesis of tetrasubstituted thiophenes for use in compound libraries

Tetrahedron letters, 1999-07, Vol.40 (30), p.5471-5474

1999

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A novel route to allenyl fluorides. Synthesis of 4-amino-7-fluorohepta-5,6-dienoic acid, the first fluoroallenyl amino acid

Journal of the American Chemical Society, 1987-05, Vol.109 (11), p.3491-3493

1987

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Allenic amino acids. 1. Synthesis of .gamma.-allenic GABA by a novel aza-Cope rearrangement

Journal of the American Chemical Society, 1984-03, Vol.106 (6), p.1877-1879

1984

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Solid-state carbon-13 NMR study of a transglutaminase-inhibitor adduct

Biochemistry (Easton), 1993-04, Vol.32 (15), p.3930-3934

1993

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[ 3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A 2B receptors

Biochemical pharmacology, 2004, Vol.68 (2), p.305-312

2004

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Design and synthesis of SH3 domain binding ligands: Modifications of the consensus sequence XPpXP

Bioorganic & medicinal chemistry letters, 1998-11, Vol.8 (22), p.3137-3142

1998

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Selective A1-adenosine receptor antagonists identified using yeast Saccharomyces cerevisiae functional assays

Bioorganic & medicinal chemistry letters, 1999-08, Vol.9 (16), p.2413-2418

1999

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Design, synthesis, activity, and structure of a novel class of matrix metalloproteinase inhibitors containing a heterocyclic P2′-P3′ amide bond isostere

Bioorganic & medicinal chemistry letters, 1996-07, Vol.6 (13), p.1601-1606

1996

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Spin trapping of hydroxyl in water: decay kinetics for the•OH and adducts to 5,5-dimethyl-1-pyrroline- N -oxide

Canadian journal of chemistry, 1983-02, Vol.61 (2), p.298-299

1983

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[3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A2B receptors

Discovery of VU2957 (Valiglurax): An mGlu 4 Positive Allosteric Modulator Evaluated as a Preclinical Candidate for the Treatment of Parkinson's Disease

Discovery of VU2957 (Valiglurax): An mGlu4 Positive Allosteric Modulator Evaluated as a Preclinical Candidate for the Treatment of Parkinson’s Disease

OSI-930 : A novel selective inhibitor of kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models

Glucokinase-activating ureas

A practical solid phase synthesis of quinazoline-2,4-diones

Leporin B: a novel hexokinase II gene inducing agent from an unidentified fungus

Potent and selective [2-imidazol-1-yl-2-(6-alkoxy-naphthalen-2-yl)-1-methyl-ethyl]-dimethyl-amines as retinoic acid metabolic blocking agents (RAMBAs)

3-[6-(2-Dimethylamino-1-imidazol-1-yl-butyl)-naphthalen-2-yloxy]-2,2-dimethyl-propionic acid as a highly potent and selective retinoic acid metabolic blocking agent

Development and kilogram-scale synthesis of mGlu5 negative allosteric modulator VU0424238 (auglurant)

Study of noncovalent enzyme—inhibitor complexes and metal binding stoichiometry of matrilysin by electrospray ionization mass spectrometry

Synthesis of Functionalized Pyridones via Palladium Catalyzed Cross Coupling Reactions

Matrilysin-inhibitor complexes: common themes among metalloproteases

Inactivation of a Cytosolic Phospholipase A2 by Thiol-Modifying Reagents: Cysteine Residues as Potential Targets of Phospholipase A2

Intriguing structure-activity relations underlie the potent inhibition of HIV protease by norstatine-based peptides

Crystal structures of matrilysin-inhibitor complexes

Practical synthesis of tetrasubstituted thiophenes for use in compound libraries

A novel route to allenyl fluorides. Synthesis of 4-amino-7-fluorohepta-5,6-dienoic acid, the first fluoroallenyl amino acid

Allenic amino acids. 1. Synthesis of .gamma.-allenic GABA by a novel aza-Cope rearrangement

Solid-state carbon-13 NMR study of a transglutaminase-inhibitor adduct

[ 3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A 2B receptors

Design and synthesis of SH3 domain binding ligands: Modifications of the consensus sequence XPpXP

Selective A1-adenosine receptor antagonists identified using yeast Saccharomyces cerevisiae functional assays

Design, synthesis, activity, and structure of a novel class of matrix metalloproteinase inhibitors containing a heterocyclic P2′-P3′ amide bond isostere

Spin trapping of hydroxyl in water: decay kinetics for the•OH and adducts to 5,5-dimethyl-1-pyrroline- N -oxide

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