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Varespladib in the Treatment of Snakebite Envenoming: Development History and Preclinical Evidence Supporting Advancement to Clinical Trials in Patients Bitten by Venomous Snakes

Toxins, 2022-11, Vol.14 (11), p.783

2022

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Cold Finger: Raynaud Phenomenon Following Snakebite Envenoming by Nikolsky’s Viper (Vipera berus nikolskii)

Toxins, 2023-10, Vol.15 (10), p.598

2023

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The BRAVO Clinical Study Protocol: Oral Varespladib for Inhibition of Secretory Phospholipase A2 in the Treatment of Snakebite Envenoming

Toxins, 2022-12, Vol.15 (1), p.22

2022

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Oral and IV Varespladib Rescue Experiments in Juvenile Pigs with Weakness Induced by Australian and Papuan Oxyuranus scutellatus Venoms

Toxins, 2023-09, Vol.15 (9), p.557

2023

Volltextzugriff (PDF)

Keel venom: Rhabdophis subminiatus (red-necked keelback) venom pathophysiologically affects diverse blood clotting pathways

Toxicon (Oxford), 2022-10, Vol.218, p.19-24

2022

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The relative efficacy of chemically diverse small-molecule enzyme-inhibitors against anticoagulant activities of Black Snake (Pseudechis spp.) venoms

Toxicology letters, 2022-08, Vol.366, p.26-32

2022

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Oral and IV Varespladib Rescue Experiments in Juvenile Pigs with Weakness Induced by Australian and Papuan IOxyuranus scutellatus/I Venoms

Toxins, 2023-09, Vol.15 (9)

2023

Volltextzugriff (PDF)

Mechanism of enhanced calcium sensitivity and alpha 2-AR vasoreactivity in chronic NOS inhibition hypertension

American journal of physiology. Heart and circulatory physiology, 2003-01, Vol.284 (1), p.H309-H316

2003

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Acute and chronic NOS inhibition enhances alpha 2- adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta

American journal of physiology. Heart and circulatory physiology, 2002-10, Vol.283 (4), p.H1361-H1369

2002

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Tyrosine kinases regulate intracellular calcium during alpha 2-adrenergic contraction in rat aorta

American journal of physiology. Heart and circulatory physiology, 2002-10, Vol.283 (4), p.H1673-H1680

2002

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LABORATORY DEMONSTRATION OF VASCULAR SMOOTH MUSCLE FUNCTION USING RAT AORTIC RING SEGMENTS

Advances in physiology education, 2000-12, Vol.24 (1), p.13-21

2000

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Acute and chronic NOS inhibition enhances alpha(2)- adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta

American journal of physiology. Heart and circulatory physiology, 2002-10, Vol.283 (4), p.H1361-H1369

2002

Volltextzugriff (PDF)

Mechanism of enhanced calcium sensitivity and alpha2-AR vasoreactivity in chronic NOS inhibition hypertension

American journal of physiology. Heart and circulatory physiology, 2003-01, Vol.53 (1), p.H309

2003

Volltextzugriff (PDF)

Mechanism of enhanced calcium sensitivity and α2-AR vasoreactivity in chronic NOS inhibition hypertension

American journal of physiology. Heart and circulatory physiology, 2003, Vol.53 (1), p.H309-H316

2003

Volltextzugriff (PDF)

Tyrosine kinases regulate intracellular calcium during alpha2-adrenergic contraction in rat aorta

American journal of physiology. Heart and circulatory physiology, 2002-10, Vol.52 (4), p.H1673

2002

Volltextzugriff (PDF)

Tyrosine kinases regulate intracellular calcium during alpha(2)-adrenergic contraction in rat aorta

American journal of physiology. Heart and circulatory physiology, 2002-10, Vol.283 (4), p.H1673-H1680

2002

Volltextzugriff (PDF)

Tyrosine kinases regulate intracellular calcium during α2-adrenergic contraction in rat aorta

American journal of physiology. Heart and circulatory physiology, 2002, Vol.52 (4), p.H1673-H1680

2002

Volltextzugriff (PDF)

Acute and chronic NOS inhibition enhances alpha2-adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta

American journal of physiology. Heart and circulatory physiology, 2002-10, Vol.52 (4), p.H1361

2002

Volltextzugriff (PDF)

Acute and chronic NOS inhibition enhances α2-adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta

American journal of physiology. Heart and circulatory physiology, 2002, Vol.52 (4), p.H1361-H1369

2002

Volltextzugriff (PDF)

Cold Finger: Raynaud Phenomenon Following Snakebite Envenoming by Nikolsky's Viper (Vipera berus nikolskii)

Toxins, 2023, Vol.15 (10)

2023

Volltextzugriff (PDF)

Mechanism of augmented alpha 2 adrenergic receptor contraction in aorta from chronic nitric oxide synthase inhibited hypertensive rats

Carter, Rebecca W

2002

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Diagnostic accuracy of mammography, clinical examination, US, and MR imaging in preoperative assessment of breast cancer

Radiology, 2004-12, Vol.233 (3), p.830

2004

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Innate Lymphocyte/Ly6C(hi) Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance

Cell, 2016-04, Vol.165 (3), p.679-689

2016

Volltextzugriff (PDF)

Enhancing face validity of mouse models of Alzheimer's disease with natural genetic variation

PLoS genetics, 2019-05, Vol.15 (5), p.e1008155-e1008155

2019

Volltextzugriff (PDF)

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Varespladib in the Treatment of Snakebite Envenoming: Development History and Preclinical Evidence Supporting Advancement to Clinical Trials in Patients Bitten by Venomous Snakes

Cold Finger: Raynaud Phenomenon Following Snakebite Envenoming by Nikolsky’s Viper (Vipera berus nikolskii)

The BRAVO Clinical Study Protocol: Oral Varespladib for Inhibition of Secretory Phospholipase A2 in the Treatment of Snakebite Envenoming

Oral and IV Varespladib Rescue Experiments in Juvenile Pigs with Weakness Induced by Australian and Papuan Oxyuranus scutellatus Venoms

Keel venom: Rhabdophis subminiatus (red-necked keelback) venom pathophysiologically affects diverse blood clotting pathways

The relative efficacy of chemically diverse small-molecule enzyme-inhibitors against anticoagulant activities of Black Snake (Pseudechis spp.) venoms

Oral and IV Varespladib Rescue Experiments in Juvenile Pigs with Weakness Induced by Australian and Papuan IOxyuranus scutellatus/I Venoms

Mechanism of enhanced calcium sensitivity and alpha 2-AR vasoreactivity in chronic NOS inhibition hypertension

Acute and chronic NOS inhibition enhances alpha 2- adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta

Tyrosine kinases regulate intracellular calcium during alpha 2-adrenergic contraction in rat aorta

A global core outcome measurement set for snakebite clinical trials

LABORATORY DEMONSTRATION OF VASCULAR SMOOTH MUSCLE FUNCTION USING RAT AORTIC RING SEGMENTS

Acute and chronic NOS inhibition enhances alpha(2)- adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta

Mechanism of enhanced calcium sensitivity and alpha2-AR vasoreactivity in chronic NOS inhibition hypertension

Mechanism of enhanced calcium sensitivity and α2-AR vasoreactivity in chronic NOS inhibition hypertension

Tyrosine kinases regulate intracellular calcium during alpha2-adrenergic contraction in rat aorta

Tyrosine kinases regulate intracellular calcium during alpha(2)-adrenergic contraction in rat aorta

Tyrosine kinases regulate intracellular calcium during α2-adrenergic contraction in rat aorta

Acute and chronic NOS inhibition enhances alpha2-adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta

Acute and chronic NOS inhibition enhances α2-adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta

Cold Finger: Raynaud Phenomenon Following Snakebite Envenoming by Nikolsky's Viper (Vipera berus nikolskii)

Mechanism of augmented alpha 2 adrenergic receptor contraction in aorta from chronic nitric oxide synthase inhibited hypertensive rats

Diagnostic accuracy of mammography, clinical examination, US, and MR imaging in preoperative assessment of breast cancer

Innate Lymphocyte/Ly6C(hi) Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance

Enhancing face validity of mouse models of Alzheimer's disease with natural genetic variation

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