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Engineering a Stable and Selective Peptide Blocker of the Kv1.3 Channel in T Lymphocytes

Molecular pharmacology, 2009-04, Vol.75 (4), p.762-773

2009

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Novel truncated isoform of SK3 potassium channel is a potent dominant-negative regulator of SK currents: implications in schizophrenia

Molecular psychiatry, 2003-05, Vol.8 (5), p.524-535

2003

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Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat : a candidate for schizophrenia and bipolar disorder?

Molecular psychiatry, 1998, Vol.3 (1), p.32-37

1998

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K + channels as targets for specific immunomodulation

Trends in pharmacological sciences (Regular ed.), 2004-05, Vol.25 (5), p.280-289

2004

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hKCa3/KCNN3 potassium channel gene : association of longer CAG repeats with schizophrenia in Israeli Ashkenazi Jews, expression in human tissues and localization to chromosome 1q21

Molecular psychiatry, 1999-05, Vol.4 (3), p.254-260

1999

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Design of a Potent and Selective Inhibitor of the Intermediate-Conductance Ca2+-Activated K+Channel, IKCa1: A Potential Immunosuppressant

Proceedings of the National Academy of Sciences - PNAS, 2000-07, Vol.97 (14), p.8151-8156

2000

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Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis

Circulation (New York, N.Y.), 2003-09, Vol.108 (9), p.1119-1125

2003

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Selective Blockade of T Lymphocyte K+Channels Ameliorates Experimental Autoimmune Encephalomyelitis, A Model for Multiple Sclerosis

Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (24), p.13942-13947

2001

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Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences

The Journal of biological chemistry, 2000-11, Vol.275 (47), p.37137-37149

2000

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Potassium Channels, Memory T Cells, and Multiple Sclerosis

The Neuroscientist, 2005-12, Vol.11 (6), p.550-562

2005

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Simplified gene nomenclature

Nature (London), 1991-07, Vol.352 (6330), p.26-26

CHANDY, K. G

1991

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Molecular properties and physiological roles of ion channels in the immune system

Journal of clinical immunology, 2001-07, Vol.21 (4), p.235-252

2001

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Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia

Molecular psychiatry, 1998-05, Vol.3 (3), p.266-269

1998

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A unified nomenclature for short-chain peptides isolated from scorpion venoms: α-KTx molecular subfamilies

Trends in pharmacological sciences (Regular ed.), 1999-11, Vol.20 (11), p.444-447

1999

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Expression and Chromosomal Localization of a Lymphocyte K+Channel Gene

Proceedings of the National Academy of Sciences - PNAS, 1990-12, Vol.87 (23), p.9411-9415

1990

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UK‐78,282, a novel piperidine compound that potently blocks the Kv1.3 voltage‐gated potassium channel and inhibits human T cell activation

British journal of pharmacology, 1999-04, Vol.126 (8), p.1707-1716

1999

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Molecular evolution of voltage-sensitive ion channel genes: on the origins of electrical excitability

Molecular biology and evolution, 1993, Vol.10 (1), p.221-242

1993

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Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines

Molecular pharmacology, 1994-06, Vol.45 (6), p.1227

1994

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Novel nonpeptide agents potently block the C-type inactivated conformation of Kv1.3 and suppress T cell activation

Molecular pharmacology, 1996-12, Vol.50 (6), p.1672-1679

1996

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Delineation of the Clotrimazole/TRAM-34 Binding Site on the Intermediate Conductance Calcium-activated Potassium Channel, IKCa1

The Journal of biological chemistry, 2001-08, Vol.276 (34), p.32040-32045

2001

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Antibodies and venom peptides: new modalities for ion channels

Nature reviews. Drug discovery, 2019-05, Vol.18 (5), p.339-357

2019

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A Novel Fluorescent Toxin to Detect and Investigate Kv1.3 Channel Up-regulation in Chronically Activated T Lymphocytes

The Journal of biological chemistry, 2003-03, Vol.278 (11), p.9928-9937

2003

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Calcium-activated potassium channels sustain calcium signaling in T lymphocytes. Selective blockers and manipulated channel expression levels

The Journal of biological chemistry, 2001-04, Vol.276 (15), p.12249-12256

2001

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functional network of ion channels in T lymphocytes

Immunological reviews, 2009-09, Vol.231 (1), p.59-87

2009

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Structural Conservation of the Pores of Calcium-activated and Voltage-gated Potassium Channels Determined by a Sea Anemone Toxin

The Journal of biological chemistry, 1999-07, Vol.274 (31), p.21885-21892

1999

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Engineering a Stable and Selective Peptide Blocker of the Kv1.3 Channel in T Lymphocytes

Novel truncated isoform of SK3 potassium channel is a potent dominant-negative regulator of SK currents: implications in schizophrenia

Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat : a candidate for schizophrenia and bipolar disorder?

K + channels as targets for specific immunomodulation

hKCa3/KCNN3 potassium channel gene : association of longer CAG repeats with schizophrenia in Israeli Ashkenazi Jews, expression in human tissues and localization to chromosome 1q21

Design of a Potent and Selective Inhibitor of the Intermediate-Conductance Ca2+-Activated K+Channel, IKCa1: A Potential Immunosuppressant

Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis

Selective Blockade of T Lymphocyte K+Channels Ameliorates Experimental Autoimmune Encephalomyelitis, A Model for Multiple Sclerosis

Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences

Potassium Channels, Memory T Cells, and Multiple Sclerosis

Simplified gene nomenclature

Molecular properties and physiological roles of ion channels in the immune system

Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia

A unified nomenclature for short-chain peptides isolated from scorpion venoms: α-KTx molecular subfamilies

Expression and Chromosomal Localization of a Lymphocyte K+Channel Gene

UK‐78,282, a novel piperidine compound that potently blocks the Kv1.3 voltage‐gated potassium channel and inhibits human T cell activation

Molecular evolution of voltage-sensitive ion channel genes: on the origins of electrical excitability

Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines

Novel nonpeptide agents potently block the C-type inactivated conformation of Kv1.3 and suppress T cell activation

Delineation of the Clotrimazole/TRAM-34 Binding Site on the Intermediate Conductance Calcium-activated Potassium Channel, IKCa1

Antibodies and venom peptides: new modalities for ion channels

A Novel Fluorescent Toxin to Detect and Investigate Kv1.3 Channel Up-regulation in Chronically Activated T Lymphocytes

Calcium-activated potassium channels sustain calcium signaling in T lymphocytes. Selective blockers and manipulated channel expression levels

functional network of ion channels in T lymphocytes

Structural Conservation of the Pores of Calcium-activated and Voltage-gated Potassium Channels Determined by a Sea Anemone Toxin

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