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Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights

Natural product reports, 2017-07, Vol.34 (7), p.712-783

2017

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Coelichelin, a new peptide siderophore encoded by the Streptomyces coelicolor genome: structure prediction from the sequence of its non-ribosomal peptide synthetase

FEMS microbiology letters, 2000-06, Vol.187 (2), p.111-114

2000

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Thioester reduction and aldehyde transamination are universal steps in actinobacterial polyketide alkaloid biosynthesis

Chemical science (Cambridge), 2017-01, Vol.8 (1), p.411-415

2017

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Structural changes in freshwater fish and chironomids exposed to bacterial exotoxins

Ecotoxicology and environmental safety, 2012-06, Vol.80, p.37-44

2012

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PCR-Targeted Streptomyces Gene Replacement Identifies a Protein Domain Needed for Biosynthesis of the Sesquiterpene Soil Odor Geosmin

Proceedings of the National Academy of Sciences - PNAS, 2003-02, Vol.100 (4), p.1541-1546

2003

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Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

Nature (London), 2002-05, Vol.417 (6885), p.141-147

2002

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Identification of a Cluster of Genes that Directs Desferrioxamine Biosynthesis in Streptomyces coelicolor M145

Journal of the American Chemical Society, 2004-12, Vol.126 (50), p.16282-16283

2004

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Substrate recognition by nonribosomal peptide synthetase multi-enzymes

Microbiology (Society for General Microbiology), 2004-06, Vol.150 (Pt 6), p.1629

2004

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Widely Distributed Bacterial Pathway for Siderophore Biosynthesis Independent of Nonribosomal Peptide Synthetases

Chembiochem : a European journal of chemical biology, 2005-04, Vol.6 (4), p.601-611

Challis, Gregory L

2005

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Mechanisms for incorporation of glycerol-derived precursors into polyketide metabolites

Journal of industrial microbiology & biotechnology, 2006-02, Vol.33 (2), p.105-120

2006

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Synergy and Contingency as Driving Forces for the Evolution of Multiple Secondary Metabolite Production by Streptomyces Species

Proceedings of the National Academy of Sciences - PNAS, 2003-11, Vol.100 (Suppl 2), p.14555-14561

2003

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Type III Polyketide Synthase β-Ketoacyl-ACP Starter Unit and Ethylmalonyl-CoA Extender Unit Selectivity Discovered by Streptomyces coelicolor Genome Mining

Journal of the American Chemical Society, 2006-11, Vol.128 (46), p.14754-14755

2006

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The vbs genes that direct synthesis of the siderophore vicibactin in Rhizobium leguminosarum: their expression in other genera requires ECF σ factor RpoI

Molecular microbiology, 2002-06, Vol.44 (5), p.1153-1166

2002

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Discovery of a new peptide natural product by Streptomyces coelicolor genome mining

Nature chemical biology, 2005-10, Vol.1 (5), p.265-269

2005

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Thioester reduction and aldehyde transamination are universal steps in actinobacterial polyketide alkaloid biosynthesisElectronic supplementary information (ESI) available: Experimental procedures and additional tables, figures, chromatograms and results from biological assays. See DOI: 10.1039/c6sc02803a

2016-12

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Thioester reduction and aldehyde transamination are universal steps in actinobacterial polyketide alkaloid biosynthesis† †Electronic supplementary information (ESI) available: Experimental procedures and additional tables, figures, chromatograms and results from biological assays. See DOI: 10.1039/c6sc02803a Click here for additional data file

Chemical science (Cambridge), 2016-08, Vol.8 (1), p.411-415

2016

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Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3(2): new mechanisms for chain initiation and termination in modular multienzymes

Chemistry & biology, 2001-08, Vol.8 (8), p.817-829

2001

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Incorporation of [U-13C]glycerol defines plausible early steps for the biosynthesis of methylenomycin A in Streptomyces coelicolor A3(2)

Chemical communications (Cambridge, England), 2001-01 (10), p.935-936

2001

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Genomic Plasticity of the Causative Agent of Melioidosis, Burkholderia pseudomallei

Proceedings of the National Academy of Sciences - PNAS, 2004-09, Vol.101 (39), p.14240-14245

2004

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Structural aspects of non-ribosomal peptide biosynthesis

Current opinion in structural biology, 2004-12, Vol.14 (6), p.748-756

2004

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Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains

Chemistry & biology, 2000-03, Vol.7 (3), p.211-224

2000

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Engineering p-Hydroxyphenylpyruvate Dioxygenase to a p-Hydroxymandelate Synthase and Evidence for the Proposed Benzene Oxide Intermediate in Homogentisate Formation

Biochemistry (Easton), 2004-01, Vol.43 (3), p.663-674

2004

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Evidence for the Unusual Condensation of a Diketide with a Pentulose in the Methylenomycin Biosynthetic Pathway of Streptomyces coelicolor A3(2)

Chembiochem : a European journal of chemical biology, 2005-12, Vol.6 (12), p.2166-2170

2005

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The vbs genes that direct synthesis of the siderophore vicibactin in Rhizobium leguminosarum: Their expression in other genera requires ECF (sigma) factor Rpol

Molecular microbiology, 2002-06, Vol.44 (5), p.1153

2002

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Towards a Biomimetic Synthesis of the Marine Alkaloids Papuamine and Haliclonadiamine: Model Studies

Tetrahedron, 2000-01, Vol.56 (4), p.623-628

2000

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Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights

Coelichelin, a new peptide siderophore encoded by the Streptomyces coelicolor genome: structure prediction from the sequence of its non-ribosomal peptide synthetase

Thioester reduction and aldehyde transamination are universal steps in actinobacterial polyketide alkaloid biosynthesis

Structural changes in freshwater fish and chironomids exposed to bacterial exotoxins

PCR-Targeted Streptomyces Gene Replacement Identifies a Protein Domain Needed for Biosynthesis of the Sesquiterpene Soil Odor Geosmin

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

Identification of a Cluster of Genes that Directs Desferrioxamine Biosynthesis in Streptomyces coelicolor M145

Substrate recognition by nonribosomal peptide synthetase multi-enzymes

Widely Distributed Bacterial Pathway for Siderophore Biosynthesis Independent of Nonribosomal Peptide Synthetases

Mechanisms for incorporation of glycerol-derived precursors into polyketide metabolites

Synergy and Contingency as Driving Forces for the Evolution of Multiple Secondary Metabolite Production by Streptomyces Species

Type III Polyketide Synthase β-Ketoacyl-ACP Starter Unit and Ethylmalonyl-CoA Extender Unit Selectivity Discovered by Streptomyces coelicolor Genome Mining

The vbs genes that direct synthesis of the siderophore vicibactin in Rhizobium leguminosarum: their expression in other genera requires ECF σ factor RpoI

Discovery of a new peptide natural product by Streptomyces coelicolor genome mining

Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3(2): new mechanisms for chain initiation and termination in modular multienzymes

Incorporation of [U-13C]glycerol defines plausible early steps for the biosynthesis of methylenomycin A in Streptomyces coelicolor A3(2)

Genomic Plasticity of the Causative Agent of Melioidosis, Burkholderia pseudomallei

Structural aspects of non-ribosomal peptide biosynthesis

Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains

Engineering p-Hydroxyphenylpyruvate Dioxygenase to a p-Hydroxymandelate Synthase and Evidence for the Proposed Benzene Oxide Intermediate in Homogentisate Formation

Evidence for the Unusual Condensation of a Diketide with a Pentulose in the Methylenomycin Biosynthetic Pathway of Streptomyces coelicolor A3(2)

The vbs genes that direct synthesis of the siderophore vicibactin in Rhizobium leguminosarum: Their expression in other genera requires ECF (sigma) factor Rpol

Towards a Biomimetic Synthesis of the Marine Alkaloids Papuamine and Haliclonadiamine: Model Studies

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