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GALV expression enhances the therapeutic efficacy of an oncolytic adenovirus by inducing cell fusion and enhancing virus distribution
Gene therapy, 2012-11, Vol.19 (11), p.1048-1057
2012
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Improved systemic antitumor therapy with oncolytic adenoviruses by replacing the fiber shaft HSG-binding domain with RGD
Gene therapy, 2012-04, Vol.19 (4), p.453-457
2012
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A modified E2F-1 promoter improves the efficacy to toxicity ratio of oncolytic adenoviruses
Gene therapy, 2009-12, Vol.16 (12), p.1441-1451
2009
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First-in-human dose-escalation study of VCN-01, a selective oncolytic adenovirus with hyaluronidase activity in patients with advanced or metastatic cancer
European journal of cancer (1990), 2016-12, Vol.69, p.S99-S100
2016
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Osteosarcoma cells as carriers to allow antitumor activity of canine oncolytic adenovirus in the presence of neutralizing antibodies
Cancer gene therapy, 2010-11, Vol.17 (11), p.792-802
2010
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Treatment of metastatic neuroblastoma with systemic oncolytic virotherapy delivered by autologous mesenchymal stem cells: an exploratory study
Cancer gene therapy, 2010-07, Vol.17 (7), p.476-483
2010
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Syncytia formation affects the yield and cytotoxicity of an adenovirus expressing a fusogenic glycoprotein at a late stage of replication
Gene therapy, 2008-09, Vol.15 (17), p.1240-1245
2008
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Control of E1A under an E2F-1 promoter insulated with the myotonic dystrophy locus insulator reduces the toxicity of oncolytic adenovirus Ad- Delta 24RGD
Cancer gene therapy, 2006-07, Vol.13 (7), p.696-705
2006
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Control of E1A under an E2F-1 promoter insulated with the myotonic dystrophy locus insulator reduces the toxicity of oncolytic adenovirus Ad-Δ24RGD
Cancer gene therapy, 2006-07, Vol.13 (7), p.696-705
2006
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The combination of i-leader truncation and gemcitabine improves oncolytic adenovirus efficacy in an immunocompetent model
Cancer gene therapy, 2014-02, Vol.21 (2), p.68-73
2014
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128TiP VCN-01 plus durvalumab in subjects with recurrent/metastatic head & neck squamous cell carcinoma (R/M HNSCC): Phase I clinical trial
Annals of oncology, 2019-12, Vol.30, p.xi47
2019
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459PProof of concept clinical study by US-guided intratumor injection of VCN-01, an oncolytic adenovirus expressing hyaluronidase in patients with pancreatic cancer
Annals of oncology, 2019-10, Vol.30 (Supplement_5)
2019
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Proof of concept clinical study by US-guided intratumor injection of VCN-01, an oncolytic adenovirus expressing hyaluronidase in patients with pancreatic cancer
Annals of oncology, 2019-10, Vol.30, p.v171-v172
2019
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459P - Proof of concept clinical study by US-guided intratumor injection of VCN-01, an oncolytic adenovirus expressing hyaluronidase in patients with pancreatic cancer
Annals of oncology, 2019-10, Vol.30, p.v171-v172
2019
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710PSystemic administration of the hyaluronidase-expressing oncolytic adenovirus VCN-01 in patients with advanced or metastatic pancreatic cancer: First-in-human clinical trial
Annals of oncology, 2019-10, Vol.30 (Supplement_5)
2019
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710P - Systemic administration of the hyaluronidase-expressing oncolytic adenovirus VCN-01 in patients with advanced or metastatic pancreatic cancer: First-in-human clinical trial
Annals of oncology, 2019-10, Vol.30, p.v271-v272
2019
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Systemic administration of the hyaluronidase-expressing oncolytic adenovirus VCN-01 in patients with advanced or metastatic pancreatic cancer: First-in-human clinical trial
Annals of oncology, 2019-10, Vol.30, p.v271-v272
2019
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302 - First-in-human dose-escalation study of VCN-01, a selective oncolytic adenovirus with hyaluronidase activity in patients with advanced or metastatic cancer
European journal of cancer (1990), 2016-12, Vol.69, p.S99-S100
2016
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Replacement of adenovirus type 5 fiber shaft heparan sulfate proteoglycan-binding domain with RGD for improved tumor infectivity and targeting
Human gene therapy, 2009-10, Vol.20 (10), p.1214-1221
2009
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Coagulation factors determine tumor transduction in vivo
Human gene therapy, 2008-12, Vol.19 (12), p.1415-1420
2008
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937P Survival outcomes in phase I trial combining VCN-01 and durvalumab (MEDI4736) in subjects with recurrent/metastatic head and neck squamous cell carcinoma refractory to previous immunotherapy treatment
Annals of oncology, 2023-10, Vol.34, p.S589-S590
2023
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Ras-dependent oncolysis with an adenovirus VAI mutant
Cancer research (Chicago, Ill.), 2003-09, Vol.63 (17), p.5544-5550
2003
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1231P Phase I study to evaluate the safety, tolerability, and efficacy of VCN-01 in combination with durvalumab (MEDI4736) in subjects with recurrent/metastatic squamous cell carcinoma of the head and neck (R/M HNSCC)
Annals of oncology, 2022-09, Vol.33, p.S1112
2022
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Adenovirus-mediated wt-p16 reintroduction induces cell cycle arrest or apoptosis in pancreatic cancer
Cancer gene therapy, 2001-10, Vol.8 (10), p.740-750
2001
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Antitumor therapy based on cellular competition
Human gene therapy, 2009-07, Vol.20 (7), p.728-738
2009
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