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Sensitivity analysis of a strongly-coupled human-based electromechanical cardiac model: Effect of mechanical parameters on physiologically relevant biomarkers

Computer methods in applied mechanics and engineering, 2020-04, Vol.361, p.112762-112762, Article 112762

2020

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ECG-based estimation of dispersion of APD restitution as a tool to stratify sotalol-induced arrhythmic risk

Journal of electrocardiology, 2015-09, Vol.48 (5), p.867-873

2015

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Slow adaptation of ventricular repolarization as a cause of arrhythmia?

Methods of information in medicine, 2014-01, Vol.53 (4), p.320-323

2014

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Improving the clinical understanding of hypertrophic cardiomyopathy by combining patient data, machine learning and computer simulations: A case study

Morphologie, 2019-12, Vol.103 (343), p.169-179

2019

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Electrocardiogram metrics identify ionic current dysregulation relevant to atrial fibrillation

European heart journal, 2022-10, Vol.43 (Supplement_2)

2022

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Characterization and modelling of the abnormal electrophysiological response under beta-adrenergic stimulation in hypertrophic cardiomyopathy

Europace (London, England), 2021-05, Vol.23 (Supplement_3)

2021

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The novel left atrial anterior 'seatbelt' line reduces sustained atrial arrhythmia by 72% compared to pulmonary vein isolation alone in a cohort of 400 virtual atria models

Europace (London, England), 2023-05, Vol.25 (Supplement_1)

2023

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Human-based computational and experimental investigation of disease mechanisms in mutation-specific hypertrophic cardiomyopathy

Europace (London, England), 2021-05, Vol.23 (Supplement_3)

2021

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Mapped Chebyshev pseudospectral method for the study of multiple scale phenomena

Computer physics communications, 2009-06, Vol.180 (6), p.912-919

2009

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Spectral smoothed boundary methods: The role of external boundary conditions

Numerical methods for partial differential equations, 2006-03, Vol.22 (2), p.435-448

2006

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Electrophysiological parameters in the electrical propagation during atrial fibrillation: A population of models study

2017 Computing in Cardiology (CinC), 2017, p.1-4

2017

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P510Whole atria mechanisms of inducibility and persistence of atrial arrhythmias by depletion of nNOS in human

Europace (London, England), 2017-06, Vol.19 (suppl_3), p.iii116-iii116

2017

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P454Balance between sodium and calcium currents determine efficacy of pharmacological antiarrhythmic strategies for atrial fibrillation

European heart journal, 2017-08, Vol.38 (suppl_1)

2017

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Cardiac Modeling

Encyclopedia of Cell Biology, 2015, p.86-94

2015

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Cell repolarization variability modulates atrial fibrillation dynamics in 3D virtual human atria

Computing in Cardiology 2013, 2013, p.911-914

2013

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Constructing human atrial electrophysiological models mimicking a patient-specific cell group

Computing in Cardiology 2014, 2014, p.761-764

2014

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Fourier spectral methods for fractional-in-space reaction-diffusion equations

BIT Numerical Mathematics, 2014-12, Vol.54 (4), p.937-954

2014

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Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block

eLife, 2019-12, Vol.8

2019

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Drug‐induced shortening of the electromechanical window is an effective biomarker for in silico prediction of clinical risk of arrhythmias

British journal of pharmacology, 2019-10, Vol.176 (19), p.3819-3833

2019

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Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization

Journal of the Royal Society interface, 2014-08, Vol.11 (97), p.20140352

2014

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Toward a broader view of mechanisms of drug cardiotoxicity

Cell reports. Medicine, 2021-03, Vol.2 (3), p.100216, Article 100216

2021

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What determines the optimal pharmacological treatment of atrial fibrillation? Insights from in silico trials in 800 virtual atria

The Journal of physiology, 2023-09, Vol.601 (18), p.4013-4032

2023

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Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (23), p.E2098-E2105

2013

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Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity

Frontiers in physiology, 2017-09, Vol.8, p.668

2017

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Sensitivity analysis of a strongly-coupled human-based electromechanical cardiac model: Effect of mechanical parameters on physiologically relevant biomarkers

ECG-based estimation of dispersion of APD restitution as a tool to stratify sotalol-induced arrhythmic risk

Slow adaptation of ventricular repolarization as a cause of arrhythmia?

Improving the clinical understanding of hypertrophic cardiomyopathy by combining patient data, machine learning and computer simulations: A case study

Electrocardiogram metrics identify ionic current dysregulation relevant to atrial fibrillation

Characterization and modelling of the abnormal electrophysiological response under beta-adrenergic stimulation in hypertrophic cardiomyopathy

The novel left atrial anterior 'seatbelt' line reduces sustained atrial arrhythmia by 72% compared to pulmonary vein isolation alone in a cohort of 400 virtual atria models

Human-based computational and experimental investigation of disease mechanisms in mutation-specific hypertrophic cardiomyopathy

Mapped Chebyshev pseudospectral method for the study of multiple scale phenomena

Spectral smoothed boundary methods: The role of external boundary conditions

Electrophysiological parameters in the electrical propagation during atrial fibrillation: A population of models study

P510Whole atria mechanisms of inducibility and persistence of atrial arrhythmias by depletion of nNOS in human

P454Balance between sodium and calcium currents determine efficacy of pharmacological antiarrhythmic strategies for atrial fibrillation

Cardiac Modeling

Cell repolarization variability modulates atrial fibrillation dynamics in 3D virtual human atria

Constructing human atrial electrophysiological models mimicking a patient-specific cell group

Fourier spectral methods for fractional-in-space reaction-diffusion equations

Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block

Drug‐induced shortening of the electromechanical window is an effective biomarker for in silico prediction of clinical risk of arrhythmias

Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization

The ‘Digital Twin’ to enable the vision of precision cardiology

Toward a broader view of mechanisms of drug cardiotoxicity

What determines the optimal pharmacological treatment of atrial fibrillation? Insights from in silico trials in 800 virtual atria

Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology

Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity

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