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Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis

Cell reports (Cambridge), 2019-11, Vol.29 (7), p.1832-1847.e8

2019

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Thioredoxin-2 Inhibits Mitochondrial Reactive Oxygen Species Generation and Apoptosis Stress Kinase-1 Activity to Maintain Cardiac Function

Circulation (New York, N.Y.), 2015-03, Vol.131 (12), p.1082-1097

2015

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Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

Science (American Association for the Advancement of Science), 2008-09, Vol.321 (5895), p.1493-1495

2008

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ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension

American journal of respiratory and critical care medicine, 2018-02, Vol.197 (3), p.373-385

2018

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ASK1 contributes to fibrosis and dysfunction in models of kidney disease

The Journal of clinical investigation, 2018-10, Vol.128 (10), p.4485-4500

2018

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The Non-Steroidal FXR Agonist Cilofexor Improves Portal Hypertension and Reduces Hepatic Fibrosis in a Rat NASH Model

Biomedicines, 2021-01, Vol.9 (1), p.60

2021

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Activation of PKCε-ALDH2 Axis Prevents 4-HNE-Induced Pain in Mice

Biomolecules (Basel, Switzerland), 2021-11, Vol.11 (12), p.1798

2021

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Apoptosis signal-regulating kinase 1 inhibition in in vivo and in vitro models of pulmonary hypertension

Pulmonary circulation, 2020-04, Vol.10 (2), p.1-16

2020

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Chronic Mild Hypoxia Protects Heart-derived H9c2 Cells against Acute Hypoxia/Reoxygenation by Regulating Expression of the SUR2A Subunit of the ATP-sensitive K+ Channel

The Journal of biological chemistry, 2003-08, Vol.278 (33), p.31444-31455

2003

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Cardioprotective mechanisms of PKC isozyme-selective activators and inhibitors in the treatment of ischemia-reperfusion injury

Pharmacological research, 2007-06, Vol.55 (6), p.523-536

2007

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Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCɛ) knockout mice

Journal of molecular and cellular cardiology, 2010-04, Vol.48 (4), p.757-764

2010

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Peptide-based urinary monitoring of fibrotic nonalcoholic steatohepatitis by mass-barcoded activity-based sensors

Science translational medicine, 2021-10, Vol.13 (616), p.eabe8939

2021

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Aldehyde Dehydrogenase 2 in Cardiac Protection: A New Therapeutic Target?

Trends in cardiovascular medicine, 2009-07, Vol.19 (5), p.158-164

2009

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Selective activation of protein kinase C∊ in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice

Journal of neuroscience research, 2013-06, Vol.91 (6), p.799-807

2013

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Hypoxia‐induced preconditioning in adult stimulated cardiomyocytes is mediated by the opening and trafficking of sarcolemmal KATP channels

The FASEB journal, 2004-06, Vol.18 (9), p.1046-1048

2004

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Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

The EMBO journal, 2003-09, Vol.22 (18), p.4666-4676

2003

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An Apoptosis Signal-regulating Kinase 1 Inhibitor Reduces Cardiomyocyte Apoptosis and Infarct Size in a Rat Ischemia-reperfusion Model

Journal of cardiovascular pharmacology, 2012-09, Vol.60 (3), p.276-282

2012

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Mitigation of radiation-induced dermatitis by activation of aldehyde dehydrogenase 2 using topical alda-1 in mice

Radiation research, 2012-07, Vol.178 (1), p.69

2012

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Creatine kinase is physically associated with the cardiac ATP‐sensitive k+ channel in vivo

The FASEB journal, 2002-01, Vol.16 (1), p.1-17

2002

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Glyceraldehyde 3-phosphate dehydrogenase serves as an accessory protein of the cardiac sarcolemmal KATP channel

EMBO reports, 2005-09, Vol.6 (9), p.848-852

2005

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17β-Estradiol regulates expression of KATP channels in heart-derived H9c2 cells

Journal of the American College of Cardiology, 2002-07, Vol.40 (2), p.367-374

2002

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3'phosphoinositide-dependent kinase-1 is essential for ischemic preconditioning of the myocardium

The FASEB journal, 2006-12, Vol.20 (14), p.2556-2558

2006

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Gender-specific difference in cardiac ATP-sensitive K+channels

Journal of the American College of Cardiology, 2001-09, Vol.38 (3), p.906-915

2001

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M-LDH serves as a sarcolemmal KATP channel subunit essential for cell protection against ischemia

The EMBO journal, 2002-08, Vol.21 (15), p.3936-3948

2002

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Mitochondrial import of PKCε is mediated by HSP90: a role in cardioprotection from ischaemia and reperfusion injury

Cardiovascular research, 2010-10, Vol.88 (1), p.83-92

2010

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Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis

Thioredoxin-2 Inhibits Mitochondrial Reactive Oxygen Species Generation and Apoptosis Stress Kinase-1 Activity to Maintain Cardiac Function

Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension

ASK1 contributes to fibrosis and dysfunction in models of kidney disease

The Non-Steroidal FXR Agonist Cilofexor Improves Portal Hypertension and Reduces Hepatic Fibrosis in a Rat NASH Model

Activation of PKCε-ALDH2 Axis Prevents 4-HNE-Induced Pain in Mice

Apoptosis signal-regulating kinase 1 inhibition in in vivo and in vitro models of pulmonary hypertension

Chronic Mild Hypoxia Protects Heart-derived H9c2 Cells against Acute Hypoxia/Reoxygenation by Regulating Expression of the SUR2A Subunit of the ATP-sensitive K+ Channel

Cardioprotective mechanisms of PKC isozyme-selective activators and inhibitors in the treatment of ischemia-reperfusion injury

Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCɛ) knockout mice

Peptide-based urinary monitoring of fibrotic nonalcoholic steatohepatitis by mass-barcoded activity-based sensors

Aldehyde Dehydrogenase 2 in Cardiac Protection: A New Therapeutic Target?

Selective activation of protein kinase C∊ in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice

Hypoxia‐induced preconditioning in adult stimulated cardiomyocytes is mediated by the opening and trafficking of sarcolemmal KATP channels

Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

An Apoptosis Signal-regulating Kinase 1 Inhibitor Reduces Cardiomyocyte Apoptosis and Infarct Size in a Rat Ischemia-reperfusion Model

Mitigation of radiation-induced dermatitis by activation of aldehyde dehydrogenase 2 using topical alda-1 in mice

Creatine kinase is physically associated with the cardiac ATP‐sensitive k+ channel in vivo

Glyceraldehyde 3-phosphate dehydrogenase serves as an accessory protein of the cardiac sarcolemmal KATP channel

17β-Estradiol regulates expression of KATP channels in heart-derived H9c2 cells

3'phosphoinositide-dependent kinase-1 is essential for ischemic preconditioning of the myocardium

Gender-specific difference in cardiac ATP-sensitive K+channels

M-LDH serves as a sarcolemmal KATP channel subunit essential for cell protection against ischemia

Mitochondrial import of PKCε is mediated by HSP90: a role in cardioprotection from ischaemia and reperfusion injury

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