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A current structural perspective on PXR and CAR in drug metabolism

Expert opinion on drug metabolism & toxicology, 2018-06, Vol.14 (6), p.635-647

2018

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Mutation of a single amino acid of pregnane X receptor switches an antagonist to agonist by altering AF-2 helix positioning

Cellular and molecular life sciences : CMLS, 2021-01, Vol.78 (1), p.317-335

2021

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Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy

Journal of medicinal chemistry, 2018-10, Vol.61 (19), p.8754-8773

2018

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Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives

Journal of medicinal chemistry, 2017-03, Vol.60 (6), p.2439-2455

2017

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A current structural perspective on PXR and CAR in drug metabolism

Expert opinion on drug metabolism & toxicology, 2018-06, Vol.14 (6), p.635-647

2018

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N,N-diethylaminobenzaldehyde (DEAB) as a substrate and mechanism-based inhibitor for human ALDH isoenzymes

Chemico-biological interactions, 2015-06, Vol.234, p.18-28

2015

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Molecular basis of crosstalk in nuclear receptors: heterodimerization between PXR and CAR and the implication in gene regulation

Nucleic acids research, 2022-04, Vol.50 (6), p.3254

2022

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Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5

Journal of the American Chemical Society, 2021-11, Vol.143 (44), p.18467-18480

2021

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Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy

European journal of medicinal chemistry, 2021-02, Vol.211, p.113060-113060, Article 113060

2021

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Discovery of a series of aromatic lactones as ALDH1/2-directed inhibitors

Chemico-biological interactions, 2015-06, Vol.234, p.38-44

2015

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Enrichment of Chemical Libraries Docked to Protein Conformational Ensembles and Application to Aldehyde Dehydrogenase 2

Journal of chemical information and modeling, 2014-07, Vol.54 (7), p.2105-2116

2014

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Unraveling the structural basis of selective inhibition of human cytochrome p450 3a5

Biophysical journal, 2022-02, Vol.121 (3), p.41a-41a

2022

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Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A

European journal of medicinal chemistry, 2021-02, Vol.211

2021

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Discovery and characterization of small molecule inhibitors of the aldehyde dehydrogenase 1/2 family

Buchman, Cameron D

2016

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Single-cell multi-omic analysis of the vestibular schwannoma ecosystem uncovers a nerve injury-like state

Nature communications, 2024-01, Vol.15 (1), p.478-478, Article 478

2024

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Temporalis muscle morphomics: the psoas of the craniofacial skeleton

The Journal of surgical research, 2014, Vol.186 (1), p.246-252

2014

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A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells

Cell reports (Cambridge), 2019-03, Vol.26 (11), p.3061-3075.e6

2019

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Effects of aging on osteogenic response and heterotopic ossification following burn injury in mice

Stem cells and development, 2015-01, Vol.24 (2), p.205

2015

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Early Unilateral Laryngeal Paralysis After Pulmonary Resection With Mediastinal Dissection for Cancer. Commetnary

The Annals of thoracic surgery, 2010, Vol.90 (4), p.1075-1079

2010

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Mumps Outbreak on a University Campus — California, 2011

MMWR. Morbidity and mortality weekly report, 2012-12, Vol.61 (48), p.986-989

2012

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Robert Wood Johnson Foundation office of promoting excellence in end-of-life care: Executive summary of the report from the field

Journal of the American College of Surgeons, 2003-05, Vol.196 (5), p.807-815

Surgeons Palliative Care Workshop

2003

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A current structural perspective on PXR and CAR in drug metabolism

Mutation of a single amino acid of pregnane X receptor switches an antagonist to agonist by altering AF-2 helix positioning

Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy

Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives

A current structural perspective on PXR and CAR in drug metabolism

N,N-diethylaminobenzaldehyde (DEAB) as a substrate and mechanism-based inhibitor for human ALDH isoenzymes

Molecular basis of crosstalk in nuclear receptors: heterodimerization between PXR and CAR and the implication in gene regulation

Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5

Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy

Discovery of a series of aromatic lactones as ALDH1/2-directed inhibitors

Enrichment of Chemical Libraries Docked to Protein Conformational Ensembles and Application to Aldehyde Dehydrogenase 2

Unraveling the structural basis of selective inhibition of human cytochrome p450 3a5

Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A

Discovery and characterization of small molecule inhibitors of the aldehyde dehydrogenase 1/2 family

Single-cell multi-omic analysis of the vestibular schwannoma ecosystem uncovers a nerve injury-like state

Temporalis muscle morphomics: the psoas of the craniofacial skeleton

A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells

Effects of aging on osteogenic response and heterotopic ossification following burn injury in mice

Early Unilateral Laryngeal Paralysis After Pulmonary Resection With Mediastinal Dissection for Cancer. Commetnary

Mumps Outbreak on a University Campus — California, 2011

Robert Wood Johnson Foundation office of promoting excellence in end-of-life care: Executive summary of the report from the field

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