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Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes

Nature structural & molecular biology, 2004-05, Vol.11 (5), p.412-419

2004

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Formation of Amyloid Fibers by Monomeric Light Chain Variable Domains

The Journal of biological chemistry, 2014-10, Vol.289 (40), p.27513-27525

2014

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Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain

eLife, 2015-11, Vol.4 (11, 2015), p.e10935-e10935

2015

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The Crystal Structure of the Complex of the Anticancer Prodrug 7-Ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica Acetylcholinesterase Provides a Molecular Explanation for Its Cholinergic Action

Molecular pharmacology, 2005-06, Vol.67 (6), p.1874-1881

2005

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Identification of Segments in Variable Domains of IG Light Chains that Drive Formation of Amyloid Fibrils

Biophysical journal, 2018-02, Vol.114 (3), p.580a-580a

2018

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Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11

Chemico-biological interactions, 2005-12, Vol.157, p.247-252

2005

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Stabilization of Variable Domain Dimers of an Immunoglobulin Light Chain Inhibits Formation of Amyloid Fibrils

Biophysical journal, 2017-02, Vol.112 (3), p.167a-167a

2017

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Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis

The Journal of biological chemistry, 2018-12, Vol.293 (51), p.19659-19671

2018

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Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability

Antimicrobial agents and chemotherapy, 2024-04, Vol.68 (4), p.e0137323-e0137323

2024

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Design and Synthesis of Novel HIV‑1 NNRTIs with Bicyclic Cores and with Improved Physicochemical Properties

Journal of medicinal chemistry, 2023-02, Vol.66 (3), p.1761-1777

2023

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Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis

The Journal of biological chemistry, 2018-12, Vol.293 (51)

2018

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3-D Structure of Serum Paraoxonase 1 Sheds Light on Its Activity, Stability, Solubility and Crystallizability

Arhiv za higijenu rada i toksikologiju, 2007-09, Vol.58 (3), p.347-353

2007

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Characterization of gene-activated human acid-β-glucosidase: Crystal structure, glycan composition, and internalization into macrophages

Glycobiology (Oxford), 2010-01, Vol.20 (1), p.24-32

2010

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Complexes of Alkylene-Linked Tacrine Dimers with Torpedo californica Acetylcholinesterase: Binding of Bis(5)-tacrine Produces a Dramatic Rearrangement in the Active-Site Gorge

Journal of medicinal chemistry, 2006-09, Vol.49 (18), p.5491-5500

2006

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Crystal Structures of Complexes of N-Butyl- and N-Nonyl-Deoxynojirimycin Bound to Acid β-Glucosidase: INSIGHTS INTO THE MECHANISM OF CHEMICAL CHAPERONE ACTION IN GAUCHER DISEASE

The Journal of biological chemistry, 2007-09, Vol.282 (39), p.29052-29058

2007

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Cyclodextrin-mediated crystallization of acid β-glucosidase in complex with amphiphilic bicyclic nojirimycin analogues

Organic & biomolecular chemistry, 2011-06, Vol.9 (11), p.4160-4167

2011

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Acid β-glucosidase: insights from structural analysis and relevance to Gaucher disease therapy

Biological chemistry, 2008-11, Vol.389 (11), p.1361-1369

2008

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6-Amino-6-deoxy-5,6-di-N-(N'-octyliminomethylidene)nojirimycin: Synthesis, Biological Evaluation, and Crystal Structure in Complex with Acid β-Glucosidase

Chembiochem : a European journal of chemical biology, 2009-06, Vol.10 (9), p.1480-1485

2009

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Structural comparison of differently glycosylated forms of acid-β-glucosidase, the defective enzyme in Gaucher disease

Acta crystallographica. Section D, Biological crystallography., 2006-12, Vol.62 (12), p.1458-1465

2006

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Control of the rate of evaporation in protein crystallization by the `microbatch under oil' method

Journal of applied crystallography, 2008-10, Vol.41 (5), p.969-971

2008

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Characterization of gene-activated human acid-b-glucosidase: Crystal structure, glycan composition, and internalization into macrophages

Glycobiology (Oxford), 2010-01, Vol.20 (1), p.24-32

2010

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Crystal Structures of Complexes of N-Butyl- and N-Nonyl-Deoxynojirimycin Bound to Acid β-Glucosidase

The Journal of biological chemistry, 2007-09, Vol.282 (39), p.29052-29058

2007

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Crystal Structures of Complexes of N-Butyl- and N-Nonyl-Deoxynojirimycin Bound to Acid Î²-Glucosidase

The Journal of biological chemistry, 2007-09, Vol.282 (39), p.29052

2007

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3D structure of mammalian paraoxonase at 2.2Å resolution

Toxicology letters, 2006-09, Vol.164, p.S9

2006

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Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge

Journal of medicinal chemistry, 2006-09, Vol.49 (18), p.5491-5500

2006

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Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes

Formation of Amyloid Fibers by Monomeric Light Chain Variable Domains

Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain

The Crystal Structure of the Complex of the Anticancer Prodrug 7-Ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica Acetylcholinesterase Provides a Molecular Explanation for Its Cholinergic Action

Identification of Segments in Variable Domains of IG Light Chains that Drive Formation of Amyloid Fibrils

Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11

Stabilization of Variable Domain Dimers of an Immunoglobulin Light Chain Inhibits Formation of Amyloid Fibrils

Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis

Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability

Design and Synthesis of Novel HIV‑1 NNRTIs with Bicyclic Cores and with Improved Physicochemical Properties

Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis

3-D Structure of Serum Paraoxonase 1 Sheds Light on Its Activity, Stability, Solubility and Crystallizability

Characterization of gene-activated human acid-β-glucosidase: Crystal structure, glycan composition, and internalization into macrophages

Complexes of Alkylene-Linked Tacrine Dimers with Torpedo californica Acetylcholinesterase: Binding of Bis(5)-tacrine Produces a Dramatic Rearrangement in the Active-Site Gorge

Crystal Structures of Complexes of N-Butyl- and N-Nonyl-Deoxynojirimycin Bound to Acid β-Glucosidase: INSIGHTS INTO THE MECHANISM OF CHEMICAL CHAPERONE ACTION IN GAUCHER DISEASE

Cyclodextrin-mediated crystallization of acid β-glucosidase in complex with amphiphilic bicyclic nojirimycin analogues

Acid β-glucosidase: insights from structural analysis and relevance to Gaucher disease therapy

6-Amino-6-deoxy-5,6-di-N-(N'-octyliminomethylidene)nojirimycin: Synthesis, Biological Evaluation, and Crystal Structure in Complex with Acid β-Glucosidase

Structural comparison of differently glycosylated forms of acid-β-glucosidase, the defective enzyme in Gaucher disease

Control of the rate of evaporation in protein crystallization by the `microbatch under oil' method

Characterization of gene-activated human acid-b-glucosidase: Crystal structure, glycan composition, and internalization into macrophages

Crystal Structures of Complexes of N-Butyl- and N-Nonyl-Deoxynojirimycin Bound to Acid β-Glucosidase

Crystal Structures of Complexes of N-Butyl- and N-Nonyl-Deoxynojirimycin Bound to Acid Î²-Glucosidase

3D structure of mammalian paraoxonase at 2.2Å resolution

Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge

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