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Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension

The New England journal of medicine, 2023-02, Vol.388 (5), p.395-405

2023

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Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

The Lancet (British edition), 2015-11, Vol.386 (10008), p.2059-2068

2015

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Aliskiren

Circulation (New York, N.Y.), 2008-08, Vol.118 (7), p.773-784

BROWN, Morris J

2008

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Development of [18F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism

Journal of medicinal chemistry, 2021-07, Vol.64 (13), p.9321-9329

2021

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Somatic Mutations Affecting the Selectivity Filter of KCNJ5 Are Frequent in 2 Large Unselected Collections of Adrenal Aldosteronomas

Hypertension (Dallas, Tex. 1979), 2012-03, Vol.59 (3), p.587-591

2012

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Comparison of the Effects of Antihypertensive Agents on Central Blood Pressure and Arterial Stiffness in Isolated Systolic Hypertension

Hypertension (Dallas, Tex. 1979), 2009-08, Vol.54 (2), p.409-413

2009

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Aliskiren and the calcium channel blocker amlodipine combination as an initial treatment strategy for hypertension control (ACCELERATE): a randomised, parallel-group trial

The Lancet (British edition), 2011-01, Vol.377 (9762), p.312-320

2011

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NEFM (Neurofilament Medium) Polypeptide, a Marker for Zona Glomerulosa Cells in Human Adrenal, Inhibits D1R (Dopamine D1 Receptor)-Mediated Secretion of Aldosterone

Hypertension (Dallas, Tex. 1979), 2017-08, Vol.70 (2), p.357-364

2017

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Transcriptome Pathway Analysis of Pathological and Physiological Aldosterone-Producing Human Tissues

Hypertension (Dallas, Tex. 1979), 2016-12, Vol.68 (6), p.1424-1431

2016

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A comparison of atenolol and nebivolol in isolated systolic hypertension

Journal of hypertension, 2008-02, Vol.26 (2), p.351-356

2008

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Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial

The lancet. Diabetes & endocrinology, 2016-02, Vol.4 (2), p.136-147

2016

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Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double‐Blind Randomized Controlled Trial

Journal of the American Heart Association, 2017-11, Vol.6 (11), p.n/a

2017

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Characterization of a novel somatic KCNJ5 mutation delI157 in an aldosterone-producing adenoma

Journal of hypertension, 2012-09, Vol.30 (9), p.1827-1833

2012

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Regulation of aldosterone secretion by Cav1.3

Scientific reports, 2016-04, Vol.6 (1), p.24697-24697, Article 24697

2016

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Rapid Diagnosis of Primary Aldosteronism: Oxymoron or One Small Step?

Hypertension (Dallas, Tex. 1979), 2017-08, Vol.70 (2), p.247-249

Brown, Morris J

2017

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Increased stroke volume and aortic stiffness contribute to isolated systolic hypertension in young adults

Hypertension (Dallas, Tex. 1979), 2005-07, Vol.46 (1), p.221-226

2005

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Baxdrostat for Treatment-Resistant Hypertension. Reply

The New England journal of medicine, 2023-05, Vol.388 (19), p.1821-1822

2023

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Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial

The Lancet (British edition), 2022-10, Vol.400 (10361), p.1417-1425

2022

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Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19

The New England journal of medicine, 2021-09, Vol.385 (12), p.1147-1149

2021

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Evaluating the role of aldosterone synthesis on adrenal cell fate

Frontiers in endocrinology (Lausanne), 2024-08, Vol.15

2024

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A common variant of the endothelial nitric oxide synthase (Glu298→Asp) is a major risk factor for coronary artery disease in the UK

Circulation (New York, N.Y.), 1999-10, Vol.100 (14), p.1515-1520

1999

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Resistant hypertension: resistance to treatment or resistance to taking treatment?

Heart (British Cardiac Society), 2014-06, Vol.100 (11), p.821-822

Brown, Morris J

2014

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Evaluation of the sensitivity and specificity of (11)C-metomidate positron emission tomography (PET)-CT for lateralizing aldosterone secretion by Conn's adenomas

The journal of clinical endocrinology and metabolism, 2012-01, Vol.97 (1), p.100-109

2012

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Randomized double-blind placebo-controlled study of an angiotensin immunotherapeutic vaccine (PMD3117) in hypertensive subjects

Clinical science (1979), 2004-08, Vol.107 (2), p.167

2004

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Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

Aliskiren

Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension

Development of [18F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism

Somatic Mutations Affecting the Selectivity Filter of KCNJ5 Are Frequent in 2 Large Unselected Collections of Adrenal Aldosteronomas

Comparison of the Effects of Antihypertensive Agents on Central Blood Pressure and Arterial Stiffness in Isolated Systolic Hypertension

Aliskiren and the calcium channel blocker amlodipine combination as an initial treatment strategy for hypertension control (ACCELERATE): a randomised, parallel-group trial

NEFM (Neurofilament Medium) Polypeptide, a Marker for Zona Glomerulosa Cells in Human Adrenal, Inhibits D1R (Dopamine D1 Receptor)-Mediated Secretion of Aldosterone

Transcriptome Pathway Analysis of Pathological and Physiological Aldosterone-Producing Human Tissues

A comparison of atenolol and nebivolol in isolated systolic hypertension

Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial

Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double‐Blind Randomized Controlled Trial

Characterization of a novel somatic KCNJ5 mutation delI157 in an aldosterone-producing adenoma

Regulation of aldosterone secretion by Cav1.3

Rapid Diagnosis of Primary Aldosteronism: Oxymoron or One Small Step?

Increased stroke volume and aortic stiffness contribute to isolated systolic hypertension in young adults

Baxdrostat for Treatment-Resistant Hypertension. Reply

Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19

Evaluating the role of aldosterone synthesis on adrenal cell fate

A common variant of the endothelial nitric oxide synthase (Glu298→Asp) is a major risk factor for coronary artery disease in the UK

Resistant hypertension: resistance to treatment or resistance to taking treatment?

Evaluation of the sensitivity and specificity of (11)C-metomidate positron emission tomography (PET)-CT for lateralizing aldosterone secretion by Conn's adenomas

Randomized double-blind placebo-controlled study of an angiotensin immunotherapeutic vaccine (PMD3117) in hypertensive subjects

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