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Synthesis of a β-strand mimetic based on a pyridine scaffold

Tetrahedron, 2006-11, Vol.62 (47), p.10937-10944

2006

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Synthesis, structure–property relationships and pharmacokinetic evaluation of ethyl 6-aminonicotinate sulfonylureas as antagonists of the P2Y12 receptor

European journal of medicinal chemistry, 2013-07, Vol.65, p.360-375

2013

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A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y12 receptor

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (10), p.2877-2881

2011

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Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats

Bioorganic & medicinal chemistry, 2011-05, Vol.19 (10), p.3039-3053

2011

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5-alkyl-1,3-oxazole derivatives of 6-amino-nicotinic acids as alkyl ester bioisosteres are antagonists of the P2Y12 receptor

Future medicinal chemistry, 2013-11, Vol.5 (17), p.2037-2056

2013

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A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y sub(12 receptor)

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (10), p.2877-2881

2011

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Design, synthesis and biological evaluation of thrombin inhibitors based on a pyridine scaffold

Organic & biomolecular chemistry, 2007-01, Vol.5 (16), p.2599-2605

2007

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A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y 12 receptor

Bioorganic & medicinal chemistry letters, 2011, Vol.21 (10), p.2877-2881

2011

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5-Alkyl-1,3-Oxazole Derivatives of 6-Amino-Nicotinic Acids as Alkyl Ester Bioisosteres are Antagonists of the P2Y 12 Receptor

Future medicinal chemistry, 2013-11, Vol.5 (17), p.2037-2056

2013

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Synthesis and biological evaluation of leucine enkephalin turn mimetics

Organic & biomolecular chemistry, 2006-02, Vol.4 (3), p.416-423

2006

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Synthesis and Conformational Studies of a β-Turn Mimetic Incorporated in Leu-enkephalin

Journal of organic chemistry, 2004-05, Vol.69 (10), p.3500-3508

2004

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Synthesis and Pharmacological Evaluation of an Analogue of the Peptide Hormone Oxytocin That Contains a Mimetic of an Inverse γ-Turn

Journal of medicinal chemistry, 2002-06, Vol.45 (12), p.2512-2519

2002

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Synthesis of Conformationally Restricted Mimetics of γ-Turns and Incorporation into Desmopressin, an Analogue of the Peptide Hormone Vasopressin

Chemistry : a European journal, 1999-08, Vol.5 (8), p.2241-2253

1999

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Conformations and Receptor Activity of Desmopressin Analogues, Which Contain γ-Turn Mimetics or a Ψ[CH2O] Isostere

Journal of medicinal chemistry, 2002-06, Vol.45 (12), p.2501-2511

2002

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[2,3]1-Thia-Wittig Rearrangements Proceeding with Complete Inversion or with Partial Loss of Configuration at the Carbanionic Center

Chemische Berichte, 1993-05, Vol.126 (5), p.1227-1239

1993

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An approach to enantiomerically pure inverse γ-turn mimetics for use in solid-phase synthesis

Tetrahedron letters, 1997-05, Vol.38 (20), p.3651-3654

1997

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Study of the regioselectivity of palladium-catalyzed monocouplings between conjugated bis(enoltriflates) and trimethylsilylacetylene

Tetrahedron letters, 1994-03, Vol.35 (13), p.1965-1968

1994

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Synthesis of 6-/10-Membered Ring Analogs of the Dienediyne Core of the Neocarzinostatin Chromophore by Palladium(0)-Mediated Ring-Closure Reactions

Liebigs Annalen, 1996-04, Vol.1996 (4), p.457-471

1996

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[2,3]-Thia-Wittig Rearrangements of α-Lithiated Sulfides Via De-aromatized Cyclohexadiene Intermediates Proceed with Inversion of Configuration at the Carbanionic Center

Chemische Berichte, 1994-10, Vol.127 (10), p.1949-1957

1994

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Synthesis of a β-strand mimetic based on a pyridine scaffold

Synthesis, structure–property relationships and pharmacokinetic evaluation of ethyl 6-aminonicotinate sulfonylureas as antagonists of the P2Y12 receptor

A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y12 receptor

Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats

5-alkyl-1,3-oxazole derivatives of 6-amino-nicotinic acids as alkyl ester bioisosteres are antagonists of the P2Y12 receptor

A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y sub(12 receptor)

Design, synthesis and biological evaluation of thrombin inhibitors based on a pyridine scaffold

A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y 12 receptor

5-Alkyl-1,3-Oxazole Derivatives of 6-Amino-Nicotinic Acids as Alkyl Ester Bioisosteres are Antagonists of the P2Y 12 Receptor

Synthesis and biological evaluation of leucine enkephalin turn mimetics

Synthesis and Conformational Studies of a β-Turn Mimetic Incorporated in Leu-enkephalin

Synthesis and Pharmacological Evaluation of an Analogue of the Peptide Hormone Oxytocin That Contains a Mimetic of an Inverse γ-Turn

Synthesis of Conformationally Restricted Mimetics of γ-Turns and Incorporation into Desmopressin, an Analogue of the Peptide Hormone Vasopressin

Conformations and Receptor Activity of Desmopressin Analogues, Which Contain γ-Turn Mimetics or a Ψ[CH2O] Isostere

[2,3]1-Thia-Wittig Rearrangements Proceeding with Complete Inversion or with Partial Loss of Configuration at the Carbanionic Center

An approach to enantiomerically pure inverse γ-turn mimetics for use in solid-phase synthesis

Study of the regioselectivity of palladium-catalyzed monocouplings between conjugated bis(enoltriflates) and trimethylsilylacetylene

Synthesis of 6-/10-Membered Ring Analogs of the Dienediyne Core of the Neocarzinostatin Chromophore by Palladium(0)-Mediated Ring-Closure Reactions

[2,3]-Thia-Wittig Rearrangements of α-Lithiated Sulfides Via De-aromatized Cyclohexadiene Intermediates Proceed with Inversion of Configuration at the Carbanionic Center

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