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Genome‐Based Identification of a Plant‐Associated Marine Bacterium as a Rich Natural Product Source

Angewandte Chemie International Edition, 2018-10, Vol.57 (44), p.14519-14523

International ed. in English, 2018

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Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids

PloS one, 2016-03, Vol.11 (3), p.e0149603

2016

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Coherence between cellular responses and in vitro splicing inhibition for the anti-tumor drug pladienolide B and its analogs

The Journal of biological chemistry, 2014-01, Vol.289 (4), p.1938-1947

2014

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Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer

Cell chemical biology, 2020-11, Vol.27 (11), p.1359-1370.e8

2020

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A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia

PLoS pathogens, 2012-09, Vol.8 (9), p.e1002922-e1002922

2012

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Image-Based 384-Well High-Throughput Screening Method for the Discovery of Skyllamycins A to C as Biofilm Inhibitors and Inducers of Biofilm Detachment in Pseudomonas aeruginosa

Antimicrobial Agents and Chemotherapy, 2014-02, Vol.58 (2), p.1092-1099

2014

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Phenotype-Guided Natural Products Discovery Using Cytological Profiling

Journal of natural products (Washington, D.C.), 2015-09, Vol.78 (9), p.2242-2248

2015

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Borrelidin B: Isolation, Biological Activity, and Implications for Nitrile Biosynthesis

Journal of natural products (Washington, D.C.), 2014-11, Vol.77 (11), p.2570-2574

2014

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An NF-κB-Based High-Throughput Screen Identifies Piericidins as Inhibitors of the Yersinia pseudotuberculosis Type III Secretion System

Antimicrobial Agents and Chemotherapy, 2014-02, Vol.58 (2), p.1118-1126

2014

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Identifying the Cellular Target of Cordyheptapeptide A and Synthetic Derivatives

ACS chemical biology, 2021-08, Vol.16 (8), p.1354-1364

2021

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Polypharmacy, Gait Performance, and Falls in Community‐Dwelling Older Adults. Results from the Gait and Brain Study

Journal of the American Geriatrics Society (JAGS), 2019-06, Vol.67 (6), p.1182-1188

2019

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An exon skipping screen identifies antitumor drugs that are potent modulators of pre-mRNA splicing, suggesting new therapeutic applications

PloS one, 2020-05, Vol.15 (5), p.e0233672-e0233672

2020

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Macrophage Cytological Profiling and Anti-Inflammatory Drug Discovery

Assay and drug development technologies, 2019-01, Vol.17 (1), p.14-16

2019

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Hit-to-lead development of the chamigrane endoperoxide merulin A for the treatment of African sleeping sickness

PloS one, 2012-09, Vol.7 (9), p.e46172

2012

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DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2–p53 Inhibitor

ACS medicinal chemistry letters, 2023-06, Vol.14 (6), p.820-826

2023

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Mechanism of action-based classification of antibiotics using high-content bacterial image analysis

Molecular bioSystems, 2013-01, Vol.9 (7), p.1837-1848

2013

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A β-Carboline Alkaloid from the Papua New Guinea Marine Sponge Hyrtios reticulatus

Journal of natural products (Washington, D.C.), 2010-02, Vol.73 (2), p.255-257

2010

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Naphthablins B and C, Meroterpenoids Identified from the Marine Sediment-Derived Streptomyces sp. CP26-58 Using HeLa Cell-Based Cytological Profiling

Journal of natural products (Washington, D.C.), 2017-03, Vol.80 (3), p.684-691

2017

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Large-scale cytological profiling for functional analysis of bioactive compounds

Molecular bioSystems, 2013-11, Vol.9 (11), p.2604

2013

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Natural Product Libraries to Accelerate the High-Throughput Discovery of Therapeutic Leads

Journal of natural products (Washington, D.C.), 2011-12, Vol.74 (12), p.2545-2555

2011

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Erratum for Duncan et al., An NF-κB-Based High-Throughput Screen Identifies Piericidins as Inhibitors of the Yersinia pseudotuberculosis Type III Secretion System

Antimicrobial agents and chemotherapy, 2016-07, Vol.60 (7), p.4427-4427

2016

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A high-throughput splicing assay identifies new classes of inhibitors of human and yeast spliceosomes

Journal of biomolecular screening, 2013-10, Vol.18 (9), p.1110-1120

2013

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A Strategy for Direct Chemical Activation of the Retinoblastoma Protein

ACS chemical biology, 2016-05, Vol.11 (5), p.1192-1197

2016

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Confirmation of the cellular targets of benomyl and rapamycin using next-generation sequencing of resistant mutants in S. cerevisiae

Molecular bioSystems, 2014-12, Vol.10 (12), p.3179-3187

2014

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Biostructural Features of Additional Jasplakinolide (Jaspamide) Analogues

Journal of natural products (Washington, D.C.), 2011-03, Vol.74 (3), p.341-351

2011

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Genome‐Based Identification of a Plant‐Associated Marine Bacterium as a Rich Natural Product Source

Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids

Coherence between cellular responses and in vitro splicing inhibition for the anti-tumor drug pladienolide B and its analogs

Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer

A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia

Image-Based 384-Well High-Throughput Screening Method for the Discovery of Skyllamycins A to C as Biofilm Inhibitors and Inducers of Biofilm Detachment in Pseudomonas aeruginosa

Phenotype-Guided Natural Products Discovery Using Cytological Profiling

Borrelidin B: Isolation, Biological Activity, and Implications for Nitrile Biosynthesis

An NF-κB-Based High-Throughput Screen Identifies Piericidins as Inhibitors of the Yersinia pseudotuberculosis Type III Secretion System

Identifying the Cellular Target of Cordyheptapeptide A and Synthetic Derivatives

Polypharmacy, Gait Performance, and Falls in Community‐Dwelling Older Adults. Results from the Gait and Brain Study

An exon skipping screen identifies antitumor drugs that are potent modulators of pre-mRNA splicing, suggesting new therapeutic applications

Macrophage Cytological Profiling and Anti-Inflammatory Drug Discovery

Hit-to-lead development of the chamigrane endoperoxide merulin A for the treatment of African sleeping sickness

DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2–p53 Inhibitor

Mechanism of action-based classification of antibiotics using high-content bacterial image analysis

A β-Carboline Alkaloid from the Papua New Guinea Marine Sponge Hyrtios reticulatus

Naphthablins B and C, Meroterpenoids Identified from the Marine Sediment-Derived Streptomyces sp. CP26-58 Using HeLa Cell-Based Cytological Profiling

Large-scale cytological profiling for functional analysis of bioactive compounds

Natural Product Libraries to Accelerate the High-Throughput Discovery of Therapeutic Leads

Erratum for Duncan et al., An NF-κB-Based High-Throughput Screen Identifies Piericidins as Inhibitors of the Yersinia pseudotuberculosis Type III Secretion System

A high-throughput splicing assay identifies new classes of inhibitors of human and yeast spliceosomes

A Strategy for Direct Chemical Activation of the Retinoblastoma Protein

Confirmation of the cellular targets of benomyl and rapamycin using next-generation sequencing of resistant mutants in S. cerevisiae

Biostructural Features of Additional Jasplakinolide (Jaspamide) Analogues

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