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Sensitizing Protective Tumor Microenvironments to Antibody-Mediated Therapy

Cell, 2014-01, Vol.156 (3), p.590-602

2014

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Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma

Cancer cell, 2017-10, Vol.32 (4), p.411-426.e11

2017

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Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation

Proceedings of the National Academy of Sciences - PNAS, 2016-07, Vol.113 (27), p.E3892-E3900

2016

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P53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest

Cancer research (Chicago, Ill.), 2008-12, Vol.68 (24), p.10094-10104

2008

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Simultaneous screening of overexpressed genes in breast cancer for oncogenic drivers and tumor dependencies

Scientific reports, 2024-06, Vol.14 (1), p.13227-13, Article 13227

2024

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Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome

The Journal of experimental medicine, 2013-03, Vol.210 (3), p.433-443

2013

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A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy

Cancer cell, 2015-11, Vol.28 (5), p.623-637

2015

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A role for PVRL4-driven cell-cell interactions in tumorigenesis

eLife, 2013-04, Vol.2, p.e00358

2013

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In vivo functional screening for systems-level integrative cancer genomics

Nature reviews. Cancer, 2020-10, Vol.20 (10), p.573

2020

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Tutorial: design and execution of CRISPR in vivo screens

Nature protocols, 2022-09, Vol.17 (9), p.1903-1925

2022

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Unraveling Tumor Suppressor Networks with In Vivo RNAi

Cell stem cell, 2013-06, Vol.12 (6), p.639-641

2013

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CLUE: a bioinformatic and wet-lab pipeline for multiplexed cloning of custom sgRNA libraries

Nucleic acids research, 2020-07, Vol.48 (13), p.e78

2020

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Functional screens identify coordinators of RNA molecule birth, life, and death as targetable cancer vulnerabilities

Current opinion in genetics & development, 2019-02, Vol.54, p.105-109

2019

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Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15), p.3127-3138

2015

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Pseudo painting/air bubble technique for planar lipid bilayers

Journal of neuroscience methods, 2014-08, Vol.233, p.13-17

2014

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A Raf-Competitive K-Ras Binder Can Fail to Functionally Antagonize Signaling

Molecular cancer therapeutics, 2018-08, Vol.17 (8), p.1773-1780

2018

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Rewiring the solid tumor epigenome for cancer therapy

Expert review of anticancer therapy, 2016-09, Vol.16 (9), p.977-987

2016

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Viral potassium channels as a robust model system for studies of membrane–protein interaction

Biochimica et biophysica acta, 2014-04, Vol.1838 (4), p.1096-1103

2014

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A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy

Cancer cell, 2015-12, Vol.28 (6), p.831-831

2015

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Cell cycle arrest or apoptosis by p53: are microRNAs-192/215 and -34 making the decision?

Cell cycle (Georgetown, Tex.), 2009-03, Vol.8 (5), p.680-681

2009

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Abstract A44: A CRISPRi screen to identify combination therapies for improved treatment of ovarian cancer

Clinical cancer research, 2020-07, Vol.26 (13_Supplement), p.A44-A44

2020

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Phagocytic Function of Macrophages Is Impaired By Chronic Lymphocytic Leukemia and high–grade Lymphoma Progression and Can be Highly Effectively Restored for Chemo-Immunotherapy

Blood, 2014-12, Vol.124 (21), p.2727-2727

2014

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Sensitizing Protective Tumor Microenvironments to Antibody-Mediated Therapy

Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma

Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation

P53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest

Simultaneous screening of overexpressed genes in breast cancer for oncogenic drivers and tumor dependencies

Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome

A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy

A role for PVRL4-driven cell-cell interactions in tumorigenesis

In vivo functional screening for systems-level integrative cancer genomics

Tutorial: design and execution of CRISPR in vivo screens

Unraveling Tumor Suppressor Networks with In Vivo RNAi

Epigenetic drug screening defines a PRMT5 inhibitor-sensitive pancreatic cancer subtype

CLUE: a bioinformatic and wet-lab pipeline for multiplexed cloning of custom sgRNA libraries

Functional screens identify coordinators of RNA molecule birth, life, and death as targetable cancer vulnerabilities

Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide

CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver

Pseudo painting/air bubble technique for planar lipid bilayers

Publisher Correction: Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia

A Raf-Competitive K-Ras Binder Can Fail to Functionally Antagonize Signaling

Rewiring the solid tumor epigenome for cancer therapy

Viral potassium channels as a robust model system for studies of membrane–protein interaction

A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy

Cell cycle arrest or apoptosis by p53: are microRNAs-192/215 and -34 making the decision?

Abstract A44: A CRISPRi screen to identify combination therapies for improved treatment of ovarian cancer

Phagocytic Function of Macrophages Is Impaired By Chronic Lymphocytic Leukemia and high–grade Lymphoma Progression and Can be Highly Effectively Restored for Chemo-Immunotherapy

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