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Fit-for-Purpose Development of the Enabling Route to Crizotinib (PF-02341066)

Organic process research & development, 2011-09, Vol.15 (5), p.1018-1026

2011

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Process Development for the Synthesis of Monocyclic β‑Lactam Core 17

Organic process research & development, 2018-02, Vol.22 (2), p.212-218

2018

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Enabled Process To Synthesize Monobactam 1 for Early Development

Organic process research & development, 2019-11, Vol.23 (11), p.2499-2509

2019

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Kiloscale Buchwald–Hartwig Amination: Optimized Coupling of Base-Sensitive 6‑Bromoisoquinoline-1-carbonitrile with (S)‑3-Amino-2-methylpropan-1-ol

Organic process research & development, 2014-12, Vol.18 (12), p.1752-1758

2014

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Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: A bench-to-bedside case study on tissue selective drug distribution

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (9), p.2725-2731

2011

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Development of an Early Enabling Synthesis for PF-03052334-02: A Novel Hepatoselective HMG-CoA Reductase Inhibitor

Organic process research & development, 2011-01, Vol.15 (1), p.148-157

2011

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The Preparation of Two, Preclinical Amino-quinazolinediones as Antibacterial Agents

Organic process research & development, 2007-05, Vol.11 (3), p.441-449

2007

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Preparation of a HMG-CoA Reductase Inhibitor via an Optimized Imidazole-Forming Condensation Reaction

Organic process research & development, 2008-11, Vol.12 (6), p.1183-1187

2008

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Electrophilic N-Amination of Two Quinazoline-2,4-diones Using Substituted (Nitrophenyl)hydroxylamines

Organic process research & development, 2002-05, Vol.6 (3), p.230-233

2002

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Development of a practical synthesis of novel, pyrrole-based HMG-CoA reductase inhibitors

Tetrahedron, 2007-08, Vol.63 (34), p.8124-8134

2007

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The efficient synthesis of (3R,4R,5R)-3-amino-4,5-dimethyl-octanoic acid, a chiral β-amino acid with potent affinity for the α2δ protein

Tetrahedron letters, 2009-03, Vol.50 (11), p.1167-1170

2009

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The efficient synthesis of (3 R,4 R,5 R)-3-amino-4,5-dimethyl-octanoic acid, a chiral β-amino acid with potent affinity for the α 2δ protein

Tetrahedron letters, 2009, Vol.50 (11), p.1167-1170

2009

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Novel, base-promoted reaction of N-alkoxycarbonyl- O-(halosubstituted 4-nitrophenyl)hydroxylamines

Tetrahedron letters, 2002-09, Vol.43 (38), p.6735-6737

2002

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COMPLEX CURVES OF DEGREE TWO CHARACTERS OF TWO-BRIDGE KNOT GROUPS (BOUNDARY CLASS, CHARACTER POLYNOMIAL)

BOYLES, DAVID C

1986

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Development of a Practical Synthesis of Novel, Pyrrole-Based HMG-CoA Reductase Inhibitors

ChemInform, 2007-11, Vol.38 (48), p.no-no

2007

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Novel, Base-Promoted Reaction of N-Alkoxycarbonyl-O-(halosubstituted 4-nitrophenyl)hydroxylamines

ChemInform, 2002-12, Vol.33 (48), p.72-72

2002

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Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance: A Randomized Clinical Trial

JAMA : the journal of the American Medical Association, 2018-09, Vol.320 (10), p.984

2018

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A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells

mBio, 2015-09, Vol.6 (5), p.e01157-e01115

2015

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Experimental infection of bats with Geomyces destructans causes white-nose syndrome

Nature (London), 2011-12, Vol.480 (7377), p.376-378

2011

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Essential in vitro diagnostics for advanced HIV and serious fungal diseases: international experts’ consensus recommendations

European journal of clinical microbiology & infectious diseases, 2019-09, Vol.38 (9), p.1581-1584

2019

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Atrial Fibrillation in Patients with Cryptogenic Stroke

The New England journal of medicine, 2014-06, Vol.370 (26), p.2467-2477

2014

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Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

Nature genetics, 2018-08, Vol.50 (8), p.1112-1121

2018

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Use of an Intrapericardial, Continuous-Flow, Centrifugal Pump in Patients Awaiting Heart Transplantation

Circulation (New York, N.Y.), 2012-06, Vol.125 (25), p.3191-3200

2012

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Diagnostic Prediction Model for Tuberculous Meningitis: An Individual Participant Data Meta-Analysis

The American journal of tropical medicine and hygiene, 2024-09, Vol.111 (3), p.546-553

2024

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Dielectric Properties of Bisphenol A Polycarbonate and Its Tethered Nitrile Analogue

Macromolecules, 2013-05, Vol.46 (10), p.4024-4033

2013

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Fit-for-Purpose Development of the Enabling Route to Crizotinib (PF-02341066)

Process Development for the Synthesis of Monocyclic β‑Lactam Core 17

Enabled Process To Synthesize Monobactam 1 for Early Development

Kiloscale Buchwald–Hartwig Amination: Optimized Coupling of Base-Sensitive 6‑Bromoisoquinoline-1-carbonitrile with (S)‑3-Amino-2-methylpropan-1-ol

Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: A bench-to-bedside case study on tissue selective drug distribution

Development of an Early Enabling Synthesis for PF-03052334-02: A Novel Hepatoselective HMG-CoA Reductase Inhibitor

The Preparation of Two, Preclinical Amino-quinazolinediones as Antibacterial Agents

Preparation of a HMG-CoA Reductase Inhibitor via an Optimized Imidazole-Forming Condensation Reaction

Electrophilic N-Amination of Two Quinazoline-2,4-diones Using Substituted (Nitrophenyl)hydroxylamines

Development of a practical synthesis of novel, pyrrole-based HMG-CoA reductase inhibitors

The efficient synthesis of (3R,4R,5R)-3-amino-4,5-dimethyl-octanoic acid, a chiral β-amino acid with potent affinity for the α2δ protein

The efficient synthesis of (3 R,4 R,5 R)-3-amino-4,5-dimethyl-octanoic acid, a chiral β-amino acid with potent affinity for the α 2δ protein

Novel, base-promoted reaction of N-alkoxycarbonyl- O-(halosubstituted 4-nitrophenyl)hydroxylamines

COMPLEX CURVES OF DEGREE TWO CHARACTERS OF TWO-BRIDGE KNOT GROUPS (BOUNDARY CLASS, CHARACTER POLYNOMIAL)

Development of a Practical Synthesis of Novel, Pyrrole-Based HMG-CoA Reductase Inhibitors

Novel, Base-Promoted Reaction of N-Alkoxycarbonyl-O-(halosubstituted 4-nitrophenyl)hydroxylamines

Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance: A Randomized Clinical Trial

A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells

Experimental infection of bats with Geomyces destructans causes white-nose syndrome

Essential in vitro diagnostics for advanced HIV and serious fungal diseases: international experts’ consensus recommendations

Atrial Fibrillation in Patients with Cryptogenic Stroke

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

Use of an Intrapericardial, Continuous-Flow, Centrifugal Pump in Patients Awaiting Heart Transplantation

Diagnostic Prediction Model for Tuberculous Meningitis: An Individual Participant Data Meta-Analysis

Dielectric Properties of Bisphenol A Polycarbonate and Its Tethered Nitrile Analogue

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